Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein

Accurate computational design of multipass transmembrane proteins

(2018) Peilong Lu et al.   SCIENCE

Modulating charge patterning and ionic strength as a strategy to induce conformational changes in intrinsically disordered proteins

(2018) Jonathan Huihui et al.   JOURNAL OF CHEMICAL PHYSICS

Evolution of a designed protein assembly encapsulating its own RNA genome

(2017) Gabriel L. Butterfield et al.   NATURE

Comprehensive computational design of ordered peptide macrocycles

(2017) Parisa Hosseinzadeh et al.   SCIENCE

Global analysis of protein folding using massively parallel design, synthesis, and testing

(2017) Gabriel J. Rocklin et al.   SCIENCE

Design of a hyperstable 60-subunit protein icosahedron

(2016) Yang Hsia et al.   NATURE

De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity

(2016) S. E. Boyken et al.   SCIENCE

Accurate design of megadalton-scale two-component icosahedral protein complexes

(2016) J. B. Bale et al.   SCIENCE

De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy

(2015) Po-Ssu Huang et al.   Nature Chemical Biology

Modulation of folding energy landscape by charge–charge interactions: Linking experiments with computational modeling

(2015) Franco O. Tzul et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic evidence for a two-stage mechanism of protein denaturation by guanidinium chloride

(2014) Santosh Kumar Jha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clusters of Branched Aliphatic Side Chains Serve As Cores of Stability in the Native State of the HisF TIM Barrel Protein

(2013) Basavanapura N. Gangadhara et al.   JOURNAL OF MOLECULAR BIOLOGY

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

(2013) R. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principles for designing ideal protein structures

(2012) Nobuyasu Koga et al.   NATURE

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

(2012) Ian Sillitoe et al.   NUCLEIC ACIDS RESEARCH

Voronoia: analyzing packing in protein structures

(2008) K. Rother et al.   NUCLEIC ACIDS RESEARCH