Dynamic changes in lung responses after single and repeated exposures to cigarette smoke in mice

Gender-specific estimates of COPD prevalence: a systematic review and meta-analysis

(2018) Georgios Ntritsos et al.   International Journal of Chronic Obstructive Pulmonary Disease

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD

(2018) Ma’en Obeidat et al.   Scientific Reports

Women manifest more severe COPD symptoms across the life course

(2018) Dawn DeMeo et al.   International Journal of Chronic Obstructive Pulmonary Disease

The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease

(2017) Gerald Burgstaller et al.   EUROPEAN RESPIRATORY JOURNAL

Gene and metabolite time-course response to cigarette smoking in mouse lung and plasma

(2017) Mikaela A. Miller et al.   PLoS One

Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice

(2017) John C. Gomez et al.   Scientific Reports

Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice

(2016) Jie Jia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

E-cigarette use results in suppression of immune and inflammatory-response genes in nasal epithelial cells similar to cigarette smoke

(2016) Elizabeth M. Martin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sex Differences in Airway Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease

(2016) Anthony Tam et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Estrogen deficiency promotes cigarette smoke–induced changes in the extracellular matrix in the lungs of aging female mice

(2016) Marilyn K. Glassberg et al.   Translational Research

Annual Healthcare Spending Attributable to Cigarette Smoking

(2015) Xin Xu et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Mechanisms of Interferon-γ Production by Neutrophils and Its Function duringStreptococcus pneumoniaePneumonia

(2015) John C. Gomez et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sex-specific features of emphysema among current and former smokers with COPD

(2015) Megan Hardin et al.   EUROPEAN RESPIRATORY JOURNAL

Identification of gene expression signature for cigarette smoke exposure response—from man to mouse

(2015) F Martin et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism

(2015) Francesca Fallarino et al.   IMMUNOBIOLOGY

Bioinformatics Analysis of the Effects of Tobacco Smoke on Gene Expression

(2015) Chunhua Cao et al.   PLoS One

Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments

(2014) Li Zuo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Airway Mucus Obstruction Triggers Macrophage Activation and Matrix Metalloproteinase 12–Dependent Emphysema

(2014) Joanna B. Trojanek et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration

(2014) Yogesh Saini et al.   BMC GENOMICS

Impact of Cigarette Smoke on the Human and Mouse Lungs: A Gene-Expression Comparison Study

(2014) Mathieu C. Morissette et al.   PLoS One

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

The Ability of Plasma Cotinine to Predict Nicotine and Carcinogen Exposure is Altered by Differences in CYP2A6: the Influence of Genetics, Race, and Sex

(2013) A. Z. X. Zhu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

COPD Surveillance—United States, 1999-2011

(2013) Earl S. Ford et al.   CHEST

Recent advances in pre-clinical mouse models of COPD

(2013) Ross Vlahos et al.   CLINICAL SCIENCE

The composition of cigarette smoke determines inflammatory cell recruitment to the lung in COPD mouse models

(2013) Gerrit John et al.   CLINICAL SCIENCE

Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor

(2013) S. D. Alsharari et al.   NICOTINE & TOBACCO RESEARCH

Short-term cigarette smoke exposure induces reversible changes in energy metabolism and cellular redox status independent of inflammatory responses in mouse lungs

(2012) Amit R. Agarwal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Live Attenuated Influenza Virus (LAIV) induces different mucosal T cell function in nonsmokers and smokers

(2012) Katherine M. Horvath et al.   CLINICAL IMMUNOLOGY

Gender Differences in Symptoms and Care Delivery for Chronic Obstructive Pulmonary Disease

(2012) Carlos H. Martinez et al.   JOURNAL OF WOMENS HEALTH

Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction

(2012) Alessandra Livraghi-Butrico et al.   PHYSIOLOGICAL GENOMICS

Early-Onset Chronic Obstructive Pulmonary Disease Is Associated with Female Sex, Maternal Factors, and African American Race in the COPDGene Study

(2011) Marilyn G. Foreman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice

(2011) Weihong Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Gender Differences of Airway Dimensions in Anatomically Matched Sites on CT in Smokers

(2011) Yu-Il Kim et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Alteration of the nasal responses to influenza virus by tobacco smoke

(2011) Terry L. Noah et al.   Current Opinion in Allergy and Clinical Immunology

Common pathogenic mechanisms and pathways in the development of COPD and lung cancer

(2011) Ian A Yang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

(2011) Zhe Zhou et al.   Journal of Cystic Fibrosis

Chronic cigarette smoking causes hypertension, increased oxidative stress, impaired NO bioavailability, endothelial dysfunction, and cardiac remodeling in mice

(2010) M. A. Hassan Talukder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Interferon-γ Production by Neutrophils during Bacterial Pneumonia in Mice

(2010) Mitsuhiro Yamada et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sex Differences in Mortality and Clinical Expressions of Patients with Chronic Obstructive Pulmonary Disease

(2010) Bartolome Celli et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tobacco Smoke Exposure and Altered Nasal Responses to Live Attenuated Influenza Virus

(2010) Terry L. Noah et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Gender differences in COPD: are women more susceptible to smoking effects than men?

(2010) I.-C. Sorheim et al.   THORAX

Airway and Lung Pathology Due to Mucosal Surface Dehydration in  -Epithelial Na+ Channel-Overexpressing Mice: Role of TNF-  and IL-4R  Signaling, Influence of Neonatal Development, and Limited Efficacy of Glucocorticoid Treatment

(2009) A. Livraghi et al.   JOURNAL OF IMMUNOLOGY

Role of CYP2A5 in the Clearance of Nicotine and Cotinine: Insights from Studies on a Cyp2a5-null Mouse Model

(2009) X. Zhou et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Short-term exposure to cigarette smoke induces endothelial dysfunction in small intrapulmonary arteries: analysis using guinea pig precision cut lung slices

(2008) J. L. Wright et al.   JOURNAL OF APPLIED PHYSIOLOGY

Development of Chronic Bronchitis and Emphysema in β-Epithelial Na+Channel–Overexpressing Mice

(2007) Marcus A. Mall et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nicotine metabolism and urinary elimination in mouse:in vitroandin vivo

(2007) H. Raunio et al.   XENOBIOTICA