Silibinin protects rat pancreatic β‐cell through up‐regulation of estrogen receptors' signaling against amylin‐ or Aβ 1–42 ‐induced reactive oxygen species/reactive nitrogen species generation

Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity

(2018) Jing Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Silibinin from Silybum marianum Stimulates Embryonic Stem Cell Vascular Differentiation via the STAT3/PI3-K/AKT Axis and Nitric Oxide

(2018) Enas Ali et al.   PLANTA MEDICA

New Evidence of Mitochondria Dysfunction in the Female Alzheimer's Disease Brain: Deficiency of Estrogen Receptor-β

(2018) Jiangang Long et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-β and islet amyloid pathologies link Alzheimer’s disease and type 2 diabetes in a transgenic model

(2017) Nadeeja Wijesekara et al.   FASEB JOURNAL

The Link between Type 2 Diabetes and Neurodegeneration: Roles for Amyloid-β, Amylin, and Tau Proteins

(2017) Prashant Bharadwaj et al.   JOURNAL OF ALZHEIMERS DISEASE

Molecular Mechanism of Binding between 17β-Estradiol and DNA

(2017) Tamsyn A. Hilder et al.   Computational and Structural Biotechnology Journal

Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro

(2016) Nan Zheng et al.   ACTA PHARMACOLOGICA SINICA

Ridaforolimus (MK-8669) synergizes with Dalotuzumab (MK-0646) in hormone-sensitive breast cancer

(2016) Marc A. Becker et al.   BMC CANCER

Estrogen receptor-β in mitochondria: implications for mitochondrial bioenergetics and tumorigenesis

(2015) Tien-Ling Liao et al.   Annals of the New York Academy of Sciences

Phosphorylation Alters Oestrogen Receptor β-Mediated Transcription in Neurones

(2015) E. Pinceti et al.   JOURNAL OF NEUROENDOCRINOLOGY

Estrogen receptor alpha phosphorylation and its functional impact in human breast cancer

(2015) Muralidharan Anbalagan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Nitric oxide in liver diseases

(2015) Yasuko Iwakiri et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Target Identification of Grape Seed Extract in Colorectal Cancer Using Drug Affinity Responsive Target Stability (DARTS) Technique: Role of Endoplasmic Reticulum Stress Response Proteins

(2014) Molly Derry et al.   CURRENT CANCER DRUG TARGETS

Silibinin ameliorates LPS-induced memory deficits in experimental animals

(2014) Ritu Joshi et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Silibinin Inhibits LPS-Induced Macrophage Activation by Blocking p38 MAPK in RAW 264.7 Cells

(2013) Cha Kyung Youn et al.   Biomolecules & Therapeutics

Inhibition of leptin gene expression and secretion by silibinin: possible role of estrogen receptors

(2012) Kazem Nejati-Koshki et al.   CYTOTECHNOLOGY

In vivorecovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of sirt-1 expression and autophagy in pancreatic β-cell

(2012) Qiong Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

The Effect of Aβ on IAPP Aggregation in the Presence of an Isolated β-Cell Membrane

(2012) Janine Seeliger et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulation of pancreatic β-cell survival by nitric oxide

(2012) Francisco J. Bedoya et al.   Islets

β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition

(2011) Catherine A. Jurgens et al.   AMERICAN JOURNAL OF PATHOLOGY

Actions of β-Amyloid Protein on Human Neurons Are Expressed through the Amylin Receptor

(2011) Jack H. Jhamandas et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification of Direct Protein Targets of Small Molecules

(2010) Brett Lomenick et al.   ACS Chemical Biology

Clinical significance of estrogen receptor phosphorylation

(2010) L. C. Murphy et al.   ENDOCRINE-RELATED CANCER

Aβ and human amylin share a common toxicity pathwayviamitochondrial dysfunction

(2010) Yun-An Lim et al.   PROTEOMICS

Steroid receptor phosphorylation: Assigning function to site-specific phosphorylation

(2009) Robert D. Ward et al.   BIOFACTORS

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

(2009) S. Zraika et al.   DIABETOLOGIA

Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways

(2009) Xiao-Ling Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Target identification using drug affinity responsive target stability (DARTS)

(2009) B. Lomenick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inducible nitric oxide synthase immunoreactivity in healthy rat pancreas.

(2008) Nurullah Keklikoglu   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA