The Binding of Human IgG to Minipig FcγRs – Implications for Preclinical Assessment of Therapeutic Antibodies
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Title
The Binding of Human IgG to Minipig FcγRs – Implications for Preclinical Assessment of Therapeutic Antibodies
Authors
Keywords
antibody effector function, FcγR, Göttingen minipig, IgG, interaction map
Journal
PHARMACEUTICAL RESEARCH
Volume 36, Issue 3, Pages -
Publisher
Springer Nature
Online
2019-02-06
DOI
10.1007/s11095-019-2574-y
References
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- (2018) Florian Cymer et al. BIOLOGICALS
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- (2017) Xinhua Wang et al. Protein & Cell
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- (2017) O. S. Qureshi et al. Scientific Reports
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- (2016) Douglas A. MacDonald et al. ANGIOGENESIS
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- (2016) Ying N. Chan et al. JOURNAL OF IMMUNOLOGY
- Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions
- (2016) Tilman Schlothauer et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Minipigs in Translational Immunosafety Sciences
- (2016) Tina Rubic-Schneider et al. TOXICOLOGIC PATHOLOGY
- The Use of Minipigs for Preclinical Safety Assessment by the Pharmaceutical Industry
- (2016) Curtis Colleton et al. TOXICOLOGIC PATHOLOGY
- The high-affinity receptor for IgG, FcγRI, of humans and non-human primates
- (2015) Alicia M. Chenoweth et al. IMMUNOLOGICAL REVIEWS
- Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI
- (2015) Masato Kiyoshi et al. Nature Communications
- Inhibitory Fc Receptor Is Required for the Maintenance of Tolerance through Distinct Mechanisms
- (2014) F. Li et al. JOURNAL OF IMMUNOLOGY
- Fc Gamma Receptor Glycosylation Modulates the Binding of IgG Glycoforms: A Requirement for Stable Antibody Interactions
- (2014) Jerrard M. Hayes et al. JOURNAL OF PROTEOME RESEARCH
- Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution
- (2014) Srinivas Akula et al. PLoS One
- Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation
- (2013) C. Lau et al. JOURNAL OF IMMUNOLOGY
- Polymorphisms and Interspecies Differences of the Activating and Inhibitory Fc RII of Macaca nemestrina Influence the Binding of Human IgG Subclasses
- (2013) H. M. Trist et al. JOURNAL OF IMMUNOLOGY
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- (2013) L. Fairbairn et al. JOURNAL OF IMMUNOLOGY
- The minipig as an alternative non-rodent model for immunogenicity testing using the TNFα blockers adalimumab and infliximab
- (2013) Geertje J. D. van Mierlo et al. Journal of Immunotoxicology
- Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions
- (2013) Friederike Jönsson et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Deciphering complex protein interaction kinetics using Interaction Map
- (2012) Danièle Altschuh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Minipig as Nonrodent Species in Toxicology—Where Are We Now?
- (2012) Niels Christian Ganderup et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
- Of Mice and Men: The Need for Humanized Mouse Models to Study Human IgG Activity in Vivo
- (2012) Anja Lux et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Different Adaptations of IgG Effector Function in Human and Nonhuman Primates and Implications for Therapeutic Antibody Treatment
- (2012) M. Warncke et al. JOURNAL OF IMMUNOLOGY
- Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration
- (2012) Yanan Zheng et al. mAbs
- Molecular cloning and characterization of a porcine Fc gamma RIIb sub-isoform(FcγRIIb1)
- (2011) Pingan Xia et al. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
- Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products
- (2010) Jan Willem van der Laan et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- The utility of the minipig as an animal model in regulatory toxicology
- (2010) Gerd Bode et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Specificity and affinity of human Fc receptors and their polymorphic variants for human IgG subclasses
- (2008) P. Bruhns et al. BLOOD
- Porcine IgG: structure, genetics, and evolution
- (2008) J. E. Butler et al. IMMUNOGENETICS
- Distinct cell-specific control of autoimmunity and infection by FcγRIIb
- (2008) Rebecca J. Brownlie et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice
- (2008) T. MEYER et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
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