The Preventive Effects and the Mechanisms of Action of Navel Orange Peel Hydroethanolic Extract, Naringin, and Naringenin in N-Acetyl-p-aminophenol-Induced Liver Injury in Wistar Rats

p53 attenuates acetaminophen-induced hepatotoxicity by regulating drug-metabolizing enzymes and transporter expression

(2018) Jiahong Sun et al.   Cell Death & Disease

Iridoid Glycosides Fraction Isolated fromVeronica ciliataFisch. Protects against Acetaminophen-Induced Liver Injury in Mice

(2017) Shancai Tan et al.   Evidence-based Complementary and Alternative Medicine

Enantioselective Modulatory Effects of Naringenin  Enantiomers on the Expression Levels of miR‐17‐3p  Involved in Endogenous Antioxidant Defenses

(2017) Valeria Curti et al.   Nutrients

Detecting mRNA Predictors of Acetaminophen-Induced Hepatotoxicity in Mouse Blood Using Quantitative Real-Time PCR

(2016) Syu-ichi Kanno et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Antioxidant and Hepatoprotective Efficiency of Selenium Nanoparticles Against Acetaminophen-Induced Hepatic Damage

(2016) Kamal Adel Amin et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Evaluation of Hepatoprotective Activity ofAdansonia digitataExtract on Acetaminophen-Induced Hepatotoxicity in Rats

(2016) Abeer Hanafy et al.   Evidence-based Complementary and Alternative Medicine

A comparative study on the antioxidant effects of hesperidin and ellagic acid against skeletal muscle ischemia/reperfusion injury

(2016) Fazile Nur Ekinci Akdemir et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Ameliorative effect of naringin in acetaminophen-induced hepatic and renal toxicity in laboratory rats: role of FXR and KIM-1

(2016) Mohammad Adil et al.   RENAL FAILURE

Hepatoprotective Effect of Pandanus odoratissimus L Inflorescence Extracts in Acetaminophen-treated Guinea Pigs

(2016) Amina El-Shaibany et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Naringenin reduces cholesterol-induced hepatic inflammation in rats by modulating matrix metalloproteinases-2, 9 via inhibition of nuclear factor κB pathway

(2015) Yassine Chtourou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Omega-3-fatty acid adds to the protective effect of flax lignan concentrate in pressure overload-induced myocardial hypertrophy in rats via modulation of oxidative stress and apoptosis

(2015) Arvindkumar E. Ghule et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Protective effects of luteolin against acetaminophen-induced acute liver failure in mouse

(2015) Minghui Tai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Wound healing potential of naringin ointment formulation via regulating the expression of inflammatory, apoptotic and growth mediators in experimental rats

(2015) Amit D. Kandhare et al.   PHARMACEUTICAL BIOLOGY

Acetaminophen hepatotoxicity: an updated review

(2014) Elizabeth M. Lancaster et al.   ARCHIVES OF TOXICOLOGY

Antioxidant and Hepatoprotective Activity of Veronica ciliata Fisch. Extracts Against Carbon Tetrachloride-Induced Liver Injury in Mice

(2014) Li Yin et al.   MOLECULES

IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples

(2014) Frency Varghese et al.   PLoS One

Review of natural products with hepatoprotective effects

(2014) Eduardo Madrigal-Santillán   WORLD JOURNAL OF GASTROENTEROLOGY

Chemistry and bioactivity of nobiletin and its metabolites

(2014) Shiming Li et al.   Journal of Functional Foods

Protective effect of naringenin against experimental colitis via suppression of Toll-like receptor 4/NF-κB signalling

(2013) Wei Dou et al.   BRITISH JOURNAL OF NUTRITION

Acetaminophen-related Hepatotoxicity

(2013) Chalermrat Bunchorntavakul et al.   Clinics in Liver Disease

Identification of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one as a strong antioxidant in glucose–histidine Maillard reaction products

(2013) Xiangying Yu et al.   FOOD RESEARCH INTERNATIONAL

In Vitro Antioxidant and Antiproliferative Activities of 5-Hydroxymethylfurfural

(2013) Ling Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Protective effect of naringenin on hepatic and renal dysfunction and oxidative stress in arsenic intoxicated rats

(2013) Sam Daniel Mershiba et al.   MOLECULAR BIOLOGY REPORTS

Chemistry and Biological Activities of Flavonoids: An Overview

(2013) Shashank Kumar et al.   TheScientificWorldJOURNAL

Hepatoprotection using sweet orange peel and its bioactive compound, hesperidin, for CCl4-induced liver injury in vivo

(2013) Shih-Ying Chen et al.   Journal of Functional Foods

Protective effect of fucoidan against acetaminophen-induced liver injury

(2012) Sang-Won Hong et al.   ARCHIVES OF PHARMACAL RESEARCH

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

(2012) Hartmut Jaeschke et al.   DRUG METABOLISM REVIEWS

Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats

(2012) Vladimir Mihailović et al.   FOOD AND CHEMICAL TOXICOLOGY

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis inLdlr−/−mice

(2012) Julia M. Assini et al.   JOURNAL OF LIPID RESEARCH

Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induced nephrotoxicity and oxidative stress in rats

(2012) Zariyantey Abdul Hamid et al.   Journal of Zhejiang University-SCIENCE B

Chemical composition of hydroethanolic extracts from Siparuna guianensis, medicinal plant used as anxiolytics in Amazon region

(2012) Giuseppina Negri et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

IFCC primary reference procedures for the measurement of catalytic activity concentrations of enzymes at 37 °C. Part 9: Reference procedure for the measurement of catalytic concentration of alkaline phosphatase

(2011) Gerhard Schumann et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity

(2011) Amr A. Fouad et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Probiotic Enterococcus lactis IITRHR1 protects against acetaminophen-induced hepatotoxicity

(2011) Sapna Sharma et al.   NUTRITION

Hesperidin alleviates acetaminophen induced toxicity in wistar rats by abrogation of oxidative stress, apoptosis and inflammation

(2011) Shiekh Tanveer Ahmad et al.   TOXICOLOGY LETTERS

TNF superfamily in inflammatory disease: translating basic insights

(2011) Michael Croft et al.   TRENDS IN IMMUNOLOGY

Molecular biology of Bax and Bak activation and action

(2010) Dana Westphal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regioselective one-pot synthesis and anti-proliferative and apoptotic effects of some novel tetrazolo[1,5-a]pyrimidine derivatives

(2010) Ahmed M. Hussein et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hepatoprotective activity of the total flavonoids from Rosa laevigata Michx fruit in mice treated by paracetamol

(2010) Yue-tao Liu et al.   FOOD CHEMISTRY

Extracts from Citrus unshiu promote immune-mediated inhibition of tumor growth in a murine renal cell carcinoma model

(2010) Sanggon Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Caspases and Kinases in a Death Grip

(2009) Manabu Kurokawa et al.   CELL

The flavonoid, carotenoid and pectin content in peels of citrus cultivated in Taiwan

(2007) Yuan-Chuen Wang et al.   FOOD CHEMISTRY