Article
Chemistry, Analytical
Chongqi Zhou, Yang Xu, Xiaonan Zhang, Zhangyan Li, Tian Guan, Yanhong Ji, Yanhong Ji
Summary: A modified weak measurement scheme, rotatory biased weak measurement, is proposed to significantly improve the sensitivity and resolution of the total internal reflection sensor. The method introduces an additional phase in the post-selected procedure and generates an extinction point in the spectrum distribution. The performance of the sensor is analyzed, and an optimal refractive index resolution of 4 x 10(-7) RIU is demonstrated.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Optics
Lauren E. Barr, Peter Karlsen, Samuel M. Hornett, Ian R. Hooper, Michal Mrnka, Christopher R. Lawrence, David B. Phillips, Euan Hendry
Summary: This study demonstrates a near-field imaging approach for subwavelength lateral resolution in images with contrast dependent on optical thickness. By using a photoactivated spatial modulator in the near field, optical thickness images can be computationally reconstructed in a few seconds. The approach was successfully applied at 140 GHz to map optical thickness variation in inhomogeneous biological tissues.
Article
Geochemistry & Geophysics
Zhiling Guo, Jingwei Xin, Nannan Wang, Jie Li, Xinbo Gao
Summary: In recent years, significant progress has been made in hyperspectral image super-resolution (HSI SR) using convolution neural networks. However, existing methods fail to consider sample-sample correlations and sparsity. Therefore, the authors propose a new HSI SR model that incorporates external-internal attention and fusion of HSI and multispectral image. Experimental results demonstrate the superiority of the proposed method.
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING
(2022)
Article
Computer Science, Hardware & Architecture
Seok Bong Yoo, Eung-Joo Lee
Summary: An optimal super-resolution imaging network based on object-adaptive optical point spread function estimation is proposed to address the issue of unknown optical blur in practical optical imaging systems. The network estimates the point spread function by a new object sharpness consistency cost in the dark channel domain and adaptively combines an object image sharpening network with the estimation. The performance of the proposed network is validated through experiments using various quantitative metrics.
IEEE CONSUMER ELECTRONICS MAGAZINE
(2021)
Article
Optics
Kevin Affannoukoue, Simon Labouesse, Guillaume Maire, Laurent Gallais, Julien Savatier, Marc Allain, Md Rasedujjaman, Loic Legoff, Jerome Idier, Renaud Poincloux, Florence Pelletier, Christophe Leterrier, Thomas Mangeat, Anne Sentenac
Summary: A benefit of random illumination microscopy (RIM) is that it improves the resolution and linearity of structured illumination microscopy using speckled illumination. In this study, RIM was implemented in the TIRF configuration for imaging biological processes close to the coverslip surface, achieving high-resolution images on fixed samples and dynamic images on live macrophages. The simplicity of the experimental setup and imaging protocol, as well as the robustness of the data processing, make TIRF-RIM a preferred method for super-resolution TIRF imaging.
Article
Environmental Sciences
Xu Lin, Qingqing Zhang, Hongyue Wang, Chaolong Yao, Changxin Chen, Lin Cheng, Zhaoxiong Li
Summary: In this study, a new DEM super-resolution reconstruction method is proposed based on the complementary relationship between internally learned and externally learned methods. By utilizing the prior information of the DEM and introducing residual learning, the method achieves better reconstruction results.
Article
Nanoscience & Nanotechnology
Yejin Park, Dokyung Jeong, Uidon Jeong, Hyunbum Park, Sungmin Yoon, Minjae Kang, Doory Kim
Summary: As the nanofabrication of polymer materials continues to advance, the local measurement of their chemical properties has become crucial due to their potential heterogeneity at the nanoscale. In this study, we developed a spectroscopic imaging approach using spectrally resolved super-resolution microscopy to characterize the nanoscale local polarity of polymer films. Our method was able to differentiate various polymer surfaces based on chemical polarities and further distinguish the polarity of functional side chain groups. Additionally, we demonstrated the ability to distinguish a two-component polymer mixture based on the contrasting polarities of the lateral phase separation, allowing for the investigation of nanoscale phase separation in polymer blends.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Environmental Sciences
Qiping Zhang, Yin Zhang, Yongchao Zhang, Yulin Huang, Jianyu Yang
Summary: Total variation (TV) is an effective method to improve azimuth resolution and preserve contour information in airborne radar imaging, but with high computational complexity. A fast TV method based on Gohberg-Semencul (GS) representation is proposed in this paper to reduce complexity by utilizing low displacement rank feature of Toeplitz matrix. The proposed method is shown to improve resolution and preserve target contour efficiently in simulation and real data processing.
Article
Chemistry, Analytical
Kunfeng Xue, Bingyong Lin, Qiukai Tang, Yuanyuan Yao, Yueliang Wang, Lifen Chen, Zuguang Li, Yanbo Zeng, Lei Li, Longhua Guo
Summary: The article introduces a paper-based 3D SERS immunoassay array for accurate detection of alpha-fetoprotein (AFP) as an early marker for hepatocellular carcinoma. The immunoassay array combines self-assembled AuNBPs@Ag nanorods, filter paper, and sandwich immunoassay to achieve high sensitivity, stability, and reproducibility.
MICROCHEMICAL JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Shubhabrata Sarkar, Pankaj Wahi, Prabhat Munshi
Summary: The study focuses on improving the performance of a table-top CT scanning instrument by proposing a new super resolution technique based on higher order total variation minimization. Experimental results show the technique can produce high resolution images from low resolution ones and outperforms existing super resolution techniques. The proposed technique is validated with experiments on different objects and shows potential as a cost-effective solution to resolution problems caused by detector size constraints in table-top CT scanning instruments.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2022)
Article
Chemistry, Analytical
Teliang Zhang, Xueliang Wang, Youjun Zeng, Songfeng Huang, Xiaoqi Dai, Weifu Kong, Qian Liu, Jiajie Chen, Junle Qu, Yonghong Shao
Summary: Surface plasmon resonance microscopy (SPRM) is widely used in biological fields for its high spatial resolution and label-free detection. In this study, a home-built SPRM system based on total internal reflection (TIR) was utilized to study the imaging of a single nanoparticle. By using a ring filter and deconvolution algorithm, the parabolic tail of the nanoparticle image was removed, achieving a spatial resolution of 248 nm. Additionally, specific binding between human IgG antigen and goat anti-human IgG antibody was successfully measured using TIR-based SPRM, demonstrating its capability in imaging sparse nanoparticles and monitoring biomolecular interactions.
Article
Biology
Jason C. Sang, Eric Hidari, Georg Meisl, Rohan T. Ranasinghe, Maria Grazia Spillantini, David Klenerman
Summary: Researchers found that cells respond to disruption of protein homeostasis by alpha-synuclein seeds primarily by secreting nanoscopic aggregates. This mechanism may represent an important protective response by cells to protein aggregation.
COMMUNICATIONS BIOLOGY
(2021)
Article
Chemistry, Physical
Jing Zeng, Wen Fan, Kangyu Jia, Shuhua Tu, Limin Wu
Summary: A novel retroreflective structural color film (RSCF) based on interference and total internal reflection (TIR) was reported. The film consists of a microscale polymer hemisphere array, displaying different colors under coaxial and noncoaxial illumination and observation. Additionally, an elastic polyurethane-based RSCF can exhibit dynamically changing colors during uniaxial tensile/compressive deformation.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Analytical
Ernesta Buzavaite-Verteliene, Vincentas Maciulis, Justina Anulyte, Tomas Tolenis, Algirdas Baskys, Ieva Plikusiene, Zigmas Balevicius
Summary: In this study, a one-dimensional photonic crystal with an additional TiO2 layer, supporting Bloch surface waves (BSW), was used to enhance the signal sensitivity for protein interaction detection. The results showed that the BSW component of the photonic crystal sample with an additional TiO2 layer had higher sensitivity.
Article
Optics
Dayong Wang, Duoxuan Ma, Kunlun Li, Yaya Zhang, Jie Zhao, Yunxin Wang, Lu Rong
Summary: In this study, total internal reflection THz digital holography is proposed and applied for measuring the dynamic refractive index (RI) distributions of solid and liquid samples. The method utilizes a prism with a pitching angle and calculates the angle and field of view from the spectrogram of the off-axis Fresnel hologram. The full-field RI distributions of solid-state soy wax and distilled water droplets are obtained, and the evaporation of an ethanol solution droplet is recorded with a temporal resolution of 10 Hz.
PHOTONICS RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Gang Ge, Yi-Zhou Zhang, Wenli Zhang, Wei Yuan, Jehad K. El-Demellawi, Peng Zhang, Enzo Di Fabrizio, Xiaochen Dong, Husam N. Alshareef
Summary: MXene serves as a versatile cross-linker in hydrogels, activating fast gelation and enhancing mechanical properties, adhesion, and self-healing ability. Multiscale molecular interactions between MXene and polymers lead to significant variations in gelation behavior among different hydrogels.
Article
Chemistry, Physical
Nayara H. Musskopf, Adair Gallo, Peng Zhang, Jeferson Petry, Himanshu Mishra
Summary: Recent research has shown that using ultrasonic humidifiers can result in higher concentrations of H2O2 in condensed water microdroplets, while condensing water droplets through heating processes lead to lower levels of H2O2 production.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Analytical
Huong Thi Thuy Nguyen, Seungah Lee, Junghwa Lee, Ji-Hyoung Ha, Seong Ho Kang
Summary: A novel enhanced multiple nanoarray BA sensor was developed using a competitive reaction in an evanescent field, showing improved detection sensitivity and a wide dynamic range for simultaneous detection of three BA molecules. The sensor was validated through high-performance liquid chromatography and enzyme-linked immunosorbent assay, demonstrating excellent enhancement of detection sensitivity through combining competitive reaction and simultaneous detection of BA-conjugated quantum dots on the multiple nanoarray sensor.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Adair Gallo, Nayara H. Musskopf, Xinlei Liu, Ziqiang Yang, Jeferson Petry, Peng Zhang, Sigurdur Thoroddsen, Hong Im, Himanshu Mishra
Summary: Recent research on the formation of hydrogen peroxide (H2O2) in water microdroplets has attracted significant attention. The presence of ozone (O-3) in the air has been found to have the most significant impact on H2O2 formation in these water microdroplets. Increased gas-liquid surface area facilitates the conversion of O-3 into H2O2.
Article
Chemistry, Multidisciplinary
Seungah Lee, Junghwa Lee, Indra Batjikh, Hyunung Yu, Seong Ho Kang
Summary: In this study, a highly sensitive hypoxia sensor based on quantum dots and gold nanodiscs was developed for the detection of HIF-1alpha in tumor cells. The sensor showed high accuracy and precision and can independently predict tumor progression and early cancer onset.
Article
Chemistry, Physical
Manola Moretti, Tania Limongi, Claudia Testi, Edoardo Milanetti, Maria Teresa De Angelis, Elvira I. Parrotta, Stefania Scalise, Gianluca Santamaria, Marco Allione, Sergei Lopatin, Bruno Torre, Peng Zhang, Monica Marini, Gerardo Perozziello, Patrizio Candeloro, Candido Fabrizio Pirri, Giancarlo Ruocco, Giovanni Cuda, Enzo Di Fabrizio
Summary: This study combines transmission electron microscopy, atomic force microscopy, and surface enhanced Raman spectroscopy to gather structural and chemical information of complex molecular systems, such as ion channels, in their original plasma membrane. It identifies the channels using two different approaches and allows a series of complementary investigations on the same sample.
Article
Chemistry, Analytical
Seungah Lee, Junghwa Lee, Seong Ho Kang
Summary: We have developed a highly sensitive fluorescence sandwich immunoassay for detecting small single molecules. Our platform utilizes gold nanoplate-based biotin antibodies and streptavidin-fluorophores instead of streptavidin-horseradish peroxidase in a microplate-based competitive ELISA. The detection limit of our assay is 5 zeptomolar (5 x 10(-21) M), which is 5.4 x 10(10) times more sensitive than the traditional turn-off format ELISA.
Article
Chemistry, Analytical
Yingying Cao, Seungah Lee, Kyungsoo Kim, Seong Ho Kang
Summary: In this study, a four-dimensional cuboid multiangle illumination-based light-sheet super-resolution (4D CMLS) imaging system was developed to overcome optical illusions in cells. The system integrated total internal reflection fluorescence and a differential interference contrast microscope, and used a rotatable cuboid prism to change the direction of light and select the optimal illumination angle. The 4D CMLS imaging method enables in-depth 4D observation of samples, making it suitable for single-molecule and subcellular organelle observations in single cells.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Junghwa Lee, Seungah Lee, Gwang Lee, Seong Ho Kang
Summary: A single-molecule fourplex nanoimmunosensor has been developed for accurate and simultaneous detection of TSH, T3, and T4. This nanoimmunosensor shows a 1015-fold higher detection sensitivity compared to the conventional enzyme-linked immunosorbent assay, making it suitable for early diagnosis and prognosis monitoring of various thyroid diseases.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Yingying Cao, Seungah Lee, Kyungsoo Kim, Jong-Young Kwak, Seong Ho Kang
Summary: Researchers have developed an integrated multifunctional light-sheet nanoscopy technique that allows for simultaneous six-dimensional tracking of anisotropic nanoparticles in single living cells. The technique utilizes wavelength-dependent scattering of light by gold nanorods to trigger signals and achieve real-time photo-switching. This technique has the potential to be used for real-time monitoring of intracellular transport in specific regions of single living cells, as well as for non-fluorescence super-resolution imaging and tracking.
Review
Chemistry, Analytical
Seungah Lee, Seong Ho Kang
Summary: Fluorescence can be enhanced or quenched depending on the distance between the metal nanoparticle surface and the fluorophore molecule. Metal-enhanced fluorescence (MEF) has promising potential in fluorescence-based biological sensing. MEF-based biosensor systems can be categorized into two platforms: two/three-dimensional scaffolds or colloidal suspensions. This review summarizes the applications of wavelength-dependent carbon dots (UV-VIS), noble metals (VIS), and upconversion nanoparticles (NIR to VIS), which contribute to the enhancement of fluorescence through resonance energy transfer modulation, and provides a perspective on this topic.
Review
Chemistry, Analytical
Yucheng Sun, Zengnan Wu, Yuting Shang, Seong Ho Kang, Jin-Ming Lin
Summary: This article provides a brief overview of the technical development, applications, challenges, and future directions in single-cell analysis using single-molecule detection-based super-resolution microscopy (SMDSRM), aiming to guide researchers in promoting the methodological development and exploring the potential of SMDSRM for single-cell analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Business
Hyewon Park, Won-Moo Hur, Seongho Kang
Summary: This study explored the effects of outcome-based control (OBCS) and behavior-based control (BBCS) on creative selling, and examined the mediation of work engagement in this relationship. The findings showed that both OBCS and BBCS were positively related to creative selling. Work engagement mediated the relationship between OBCS and creative selling but not between BBCS and creative selling. The joint effect of OBCS and BBCS on work engagement was found to be hierarchical, with high OBCS and low BBCS leading to higher work engagement.
JOURNAL OF RETAILING AND CONSUMER SERVICES
(2023)
Article
Chemistry, Physical
Zi Qiang Yang, Peng Zhang, Meng Shi, Ali Al Julaih, Himanshu Mishra, Enzo Di Fabrizio, Sigurdur T. Thoroddsen
Summary: Polymer filaments have important applications in biology, tissue engineering, and molecular machines. Researchers have developed a simple method to deposit stretched polymer fibers between micro-pillars, allowing for characterization of filament-forming configurations and their properties.
