Article
Engineering, Environmental
Robert Groth, Sadegh Niazi, Graham R. Johnson, Zoran Ristovski
Summary: The impact of respiratory particle composition on morphology and phase is not well understood. This study constructed physiologically relevant respiratory fluid analogues and found a relationship between hygroscopicity and protein concentration. The salt component of respiratory particles can crystallize in different forms, and respiratory particles can exist in a glassy or viscoelastic state. The morphology and phase of respiratory particles may influence the viability of embedded pathogens.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Robert Groth, Sadegh Niazi, Graham R. Johnson, Zoran Ristovski
Summary: This study investigates the impact of respiratory particle composition on their morphology and phase, as well as the effects of different phases and morphologies on the viability of viruses embedded within the particles. The results show that the salt component of respiratory particles can crystallize in different ways, and protein particles can exist in either a glassy or viscoelastic state under indoor conditions. The phase and morphology of respiratory particles may influence the viability of embedded pathogens. The study recommends using a protein concentration of at least 90% when simulating the native composition of respiratory fluid to improve the representativity of the pathogen's microenvironment.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Chemical
Wei Guo, Jingqiao Li, Rogerio Manica, Tianzi Bai, Mingda Li, Yi Lu, Haijun Zhang, Qingxia Liu
Summary: This study investigated the interaction forces between a bubble and a scheelite surface, and explored the effects of sodium oleate and calcium ions on bubble attachment. The results showed that the electrical double layer force inhibited the scheelite-bubble attachment, and adding sodium oleate hydrophobized the scheelite surface, allowing hydrophobic attraction to dominate attachment. Adding calcium ions weakened the repulsive force and increased interfacial tension, facilitating bubble attachment. These findings provide a better understanding of bubble-scheelite attachment in mineral flotation.
MINERALS ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Maxim Ziatdinov, Shuai Zhang, Orion Dollar, Jim Pfaendtner, Christopher J. Mundy, Xin Li, Harley Pyles, David Baker, James J. De Yoreo, Sergei Kalinin
Summary: High-speed atomic force microscopy is used to visualize the dynamics of protein self-assembly on inorganic surfaces and the resulting geometric patterns. Unsupervised linear unmixing is utilized to explore the time dynamics of classical macroscopic descriptors and establish the presence of static ordered and dynamic disordered phases. Deep learning-based workflow is developed to analyze particle dynamics and identify particle behavior classes through feature extraction and mixture modeling.
Article
Nanoscience & Nanotechnology
Shidong Li, Anqi Sng, Dan Daniel, Hon Chung Lau, Ole Torsaeter, Ludger P. Stubbs
Summary: Silica nanoparticles or nanofluids can alter the wettability of surfaces, making them hydrophilic and oil-repellent under water. The adsorption of nanoparticles onto surfaces forms a porous layer that reduces contact between oil droplets and solid substrates, thereby significantly lowering the adhesion force.Experimental findings suggest that even a small addition of nanoparticles can improve oil recovery rates in micro-models with glass channels resembling physical rock networks.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Anna Petrova, Mikhail Zakharov, Marina Ageeva, Ryan McKenzie, Tatyana Gorshkova, Michael Deyholos, Liudmila Kozlova
Summary: Intrusive growth is a type of cell growth where a cell exceeds the growth rate of its neighbors and extends longer. Fibers, the most abundant cell type in plant mechanical tissues, play a fundamental role in the production of textiles and other materials. A mutant of flax, known as reduced fiber 1 (rdf), has impaired intrusive growth in both phloem and xylem. This mutant provides insights into the molecular mechanisms and principles of plant mechanical tissue functioning.
Review
Physics, Applied
Jason Pan, Tommy Kmieciak, Yen-Ting Liu, Matthew Wildenradt, Yun-Sheng Chen, Yang Zhao
Summary: This review focuses on two main promising technologies for probing forces at the single molecule level in live cells. It reviews their theoretical fundamentals, recent technical advancements, and future directions.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Entomology
Steven Huth, Lisa-Maricia Schwarz, Stanislav N. Gorb
Summary: This study investigates the adhesive properties of Hypochaeris radicata pollen and the dependence on pollen aging by quantifying the pull-off forces from glass slides. The results show that the adhesion between pollen and glass increases over time as the pollen ages.
Article
Biochemistry & Molecular Biology
Rico Schieweck, Elisa-Charlott Schoeneweiss, Max Harner, Daniela Rieger, Christin Illig, Barbara Sacca, Bastian Popper, Michael A. Kiebler
Summary: RNA-binding proteins are essential regulators controlling cellular transcriptome and translatome, with the Pumilio protein family being highly expressed in cancer cells and regulated by bFGF. Pum2 selectively enhances eIF4E translation and plays a crucial role in the growth of mature neurons.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nanoscience & Nanotechnology
Keivan Asadi, Junghoon Yeom, Hanna Cho
Summary: Investigating internal resonance (IR) mechanisms in micro/nanoresonators reveals that intermodal coupling between second and third flexural modes in asymmetric structures provides an optimal condition for strong IR, with high energy transfer to the resonated mode. This study introduces design strategies that can be easily integrated into typical micro/nanoelectromechanical systems, offering potential for paradigm-shifting applications in micro/nanosystems.
MICROSYSTEMS & NANOENGINEERING
(2021)
Editorial Material
Multidisciplinary Sciences
Telmo O. Paiva, Albertus Viljoen, Yves F. Dufrene
Summary: Advancements in atomic force microscopy (AFM) techniques and methodologies in microbiology have enhanced our understanding of microbial cell surfaces. Recent studies have shown that AFM imaging of cells and membranes at or near molecular resolution enables detailed visualization of membrane-drug interactions.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Nathane C. Mebus-Antunes, Wellington S. Ferreira, Glauce M. Barbosa, Thais C. Neves-Martins, Gilberto Weissmuller, Fabio C. L. Almeida, Andrea T. Da Poian
Summary: This study establishes the conditions for in vitro assembly of DENV nucleocapsid-like particles (NCLPs) using recombinant DENVC. The assembly process is concentration-dependent and involves DENVC charge neutralization. The results shed light on the assembly mechanism of DENV and have important implications for understanding the virus.
Article
Chemistry, Multidisciplinary
Devon S. Jakob, Nengxu Li, Huanping Zhou, Xiaoji G. Xu
Summary: This article introduces a novel method to generate Coulombic force in KPFM, increasing the spatial resolution to approximately 25 nm. By integrating PiFM, high spatial resolution chemical distributions and surface potential maps can be obtained concurrently. This is expected to facilitate characterizations of nanoscale electrical properties of photoactive materials, semiconductors, and ferroelectric materials.
Article
Materials Science, Characterization & Testing
Ilya A. Morozov
Summary: Polyurethane elastomer was studied by atomic force microscopy under fast nanoindentation conditions to investigate surface characteristics. The research found that the hard phase is unevenly distributed with the soft phase, and the indentation rate is influenced by various factors.
Article
Chemistry, Multidisciplinary
Jacopo Vialetto, Fabrizio Camerin, Shivaprakash N. Ramakrishna, Emanuela Zaccarelli, Lucio Isa
Summary: The encapsulation of a rigid core within a soft polymeric shell allows obtaining composite colloidal particles with retained functional properties. The authors investigated the interfacial morphology of these particles and identified that the core properties, shell thicknesses, and grafting density can influence their conformation. By understanding their wetting behavior, these composite particles can be designed to exhibit specific inter-particle interactions for the stabilization of interfaces and the fabrication of tailored 2D materials with functional properties.
Article
Engineering, Environmental
Armando D. Estillore, Anusha P. S. Hettiyadura, Zhen Qin, Erin Leckrone, Becky Wombacher, Tim Humphry, Elizabeth A. Stone, Vicki H. Grassian
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2016)
Article
Chemistry, Physical
Mingjin Tang, Jennifer M. Alexander, Deokhyeon Kwon, Armando D. Estillore, Olga Laskina, Mark A. Young, Paul D. Kleiber, Vicki H. Grassian
JOURNAL OF PHYSICAL CHEMISTRY A
(2016)
Article
Chemistry, Physical
Jonathan V. Trueblood, Armando D. Estillore, Christopher Lee, Jacqueline A. Dowling, Kimberly A. Prather, Vicki H. Grassian
JOURNAL OF PHYSICAL CHEMISTRY A
(2016)
Review
Chemistry, Multidisciplinary
Armando D. Estillore, Jonathan V. Trueblood, Vicki H. Grassian
Article
Chemistry, Physical
Armando D. Estillore, Holly S. Morris, Victor W. Or, Hansol D. Lee, Michael R. Alves, Meagan A. Marciano, Olga Laskina, Zhen Qin, Alexei V. Tivanski, Vicki H. Grassian
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2017)
Article
Chemistry, Multidisciplinary
Richard E. Cochran, Olga Laskina, Jonathan V. Trueblood, Armando D. Estillore, Holly S. Morris, Thilina Jayarathne, Camille M. Sultana, Christopher Lee, Peng Lin, Julia Laskin, Alexander Laskin, Jacqueline A. Dowling, Zhen Qin, Christopher D. Cappa, Timothy H. Bertram, Alexei V. Tivanski, Elizabeth A. Stone, Kimberly A. Prather, Vicki H. Grassian
Article
Chemistry, Analytical
Victor W. Or, Armando D. Estillore, Alexei V. Tivanski, Vicki H. Grassian
Article
Chemistry, Physical
Oleksandr Yefanov, Dominik Oberthuer, Richard Bean, Max O. Wiedorn, Juraj Knoska, Gisel Pena, Salah Awel, Lars Gumprecht, Martin Domaracky, Iosifina Sarrou, P. Lourdu Xavier, Markus Metz, Sasa Bajt, Valerio Mariani, Yaroslav Gevorkov, Thomas A. White, Aleksandra Tolstikova, Pablo Villanueva-Perez, Carolin Seuring, Steve Aplin, Armando D. Estillore, Jochen Kuepper, Alexander Klyuev, Manuela Kuhn, Torsten Laurus, Heinz Graafsma, Diana C. F. Monteiro, Martin Trebbin, Filipe R. N. C. Maia, Francisco Cruz-Mazo, Alfonso M. Ganan-Calvo, Michael Heymann, Connie Darmanin, Brian Abbey, Marius Schmidt, Petra Fromme, Klaus Giewekemeyer, Marcin Sikorski, Rita Graceffa, Patrik Vagovic, Thomas Kluyver, Martin Bergemann, Hans Fangohr, Jolanta Sztuk-Dambietz, Steffen Hauf, Natascha Raab, Valerii Bondar, Adrian P. Mancuso, Henry Chapman, Anton Barty
STRUCTURAL DYNAMICS-US
(2019)
Article
Chemistry, Physical
Amit K. Samanta, Muhamed Amin, Armando D. Estillore, Nils Roth, Lena Worbs, Daniel A. Horke, Jochen Kuepper
STRUCTURAL DYNAMICS-US
(2020)
Article
Optics
Kartik Ayyer, P. Lourdu Xavier, Johan Bielecki, Zhou Shen, Benedikt J. Daurer, Amit K. Samanta, Salah Awel, Richard Bean, Anton Barty, Martin Bergemann, Tomas Ekeberg, Armando D. Estillore, Hans Fangohr, Klaus Giewekemeyer, Mark S. Hunter, Mikhail Karnevskiy, Richard A. Kirian, Henry Kirkwood, Yoonhee Kim, Jayanath Koliyadu, Holger Lange, Romain Letrun, Jannik Lubke, Thomas Michelat, Andrew J. Morgan, Nils Roth, Tokushi Sato, Margin Sikorski, Florian Schulz, John C. H. Spence, Patrik Vagovic, Tamme Wollweber, Lena Worbs, Oleksandr Yefanov, Yulong Zhuang, Filipe R. N. C. Maia, Daniel A. Horke, Jochen Kuepper, N. Duane Loh, Adrian P. Mancuso, Henry N. Chapman
Summary: Single particle imaging at XFELs has the potential to determine the structure and dynamics of single biomolecules at room temperature. By overcoming hurdles in collecting high-quality diffraction patterns and computational purification, researchers have successfully obtained sub-nano meter resolution 3D reconstructions for biomolecular imaging. These advancements in X-ray sources, detectors, sample delivery, and data analysis algorithms illuminate new possibilities for characterizing diverse ensembles at the structural level.
Article
Chemistry, Physical
Jannik Luebke, Nils Roth, Lena Worbs, Daniel A. Horke, Armando D. Estillore, Amit K. Samanta, Jochen Kuepper
Summary: In single-particle imaging experiments, researchers observed the charging of 220 nm polystyrene particles in an aerosol beam created by a gas-dynamic virtual nozzle focusing technique, without intentional charging of the nanoparticles. They propose a deflection method for detecting and characterizing the charge states of aerosolized nanoparticles, and their analysis using optical light-sheet localization microscopy and quantitative particle trajectory simulations supports previous descriptions of skewed charging probabilities of triboelectrically charged nanoparticles.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Yulong Zhuang, Salah Awel, Anton Barty, Richard Bean, Johan Bielecki, Martin Bergemann, Benedikt J. Daurer, Tomas Ekeberg, Armando D. Estillore, Hans Fangohr, Klaus Giewekemeyer, Mark S. Hunter, Mikhail Karnevskiy, Richard A. Kirian, Henry Kirkwood, Yoonhee Kim, Jayanath Koliyadu, Holger Lange, Romain Letrun, Jannik Luebke, Abhishek Mall, Thomas Michelat, Andrew J. Morgan, Nils Roth, Amit K. Samanta, Tokushi Sato, Zhou Shen, Marcin Sikorski, Florian Schulz, John C. H. Spence, Patrik Vagovic, Tamme Wollweber, Lena Worbs, P. Lourdu Xavier, Oleksandr Yefanov, Filipe R. N. C. Maia, Daniel A. Horke, Jochen Kuepper, N. Duane Loh, Adrian P. Mancuso, Henry N. Chapman, Kartik Ayyer
Summary: One of the outstanding problems in X-ray single-particle imaging is the classification of structural heterogeneity. This paper proposes two methods that can account for orientation-induced variation and determine the structural landscape of a sample ensemble. The methods are validated using experimental data and can recover discrete structural classes and continuous deformations.
Proceedings Paper
Optics
Mauro Prasciolu, Kevin T. Murray, Nikolay Ivanov, Holger Fleckenstein, Martin Domaracky, Luca Gelisio, Fabian Trost, Kartik Ayyer, Dietrich Krebs, Steve Aplin, Salah Awel, Ulrike Boesenberg, Grega Belsak, Anton Barty, Armando D. Estillore, Matthias Fuchs, Yaroslav Gevorkov, Joerg Hallmann, Chan Kim, Juraj Knoska, Jochen Kuepper, Chufeng Li, Wei Lu, Valerio Mariani, Andrew J. Morgan, Johannes Moeller, Anders Madsen, Dominik Oberthuer, Gisel E. Pena Murillo, David A. Reis, Markus Scholz, Bozidar Sarler, Pablo Villanueva-Perez, Oleksandr Yefanov, Kara A. Zielinski, Alexey Zozulya, Henry N. Chapman, Sasa Bajt
Summary: This paper reports on the use of multilayer Laue lenses to focus the intense X-ray Free Electron Laser beam at the European XFEL to a spot size of a few tens of nanometers. The procedure for aligning and characterizing these lenses is presented, along with the discussion of challenges faced when working with the pulse trains from this unique x-ray source.
INTERNATIONAL CONFERENCE ON X-RAY LASERS 2020
(2021)
Article
Chemistry, Physical
Hansol D. Lee, Armando D. Estillore, Holly S. Morris, Kamal K. Ray, Aldair Alejandro, Vicki H. Grassian, Alexei V. Tivanski
JOURNAL OF PHYSICAL CHEMISTRY A
(2017)