Apn2 resolves blocked 3′ ends and suppresses Top1-induced mutagenesis at genomic rNMP sites

APE2 promotes DNA damage response pathway from a single-strand break

(2018) Yunfeng Lin et al.   NUCLEIC ACIDS RESEARCH

APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress

(2016) Bret D. Wallace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of DNA helicases and Exo1 in the avoidance of mutations induced by Top1-mediated cleavage at ribonucleotides in DNA

(2015) Hengyao Niu et al.   CELL CYCLE

Error-free and mutagenic processing of topoisomerase 1-provoked damage at genomic ribonucleotides

(2015) J. L. Sparks et al.   EMBO JOURNAL

Topoisomerase I Alone Is Sufficient to Produce Short DNA Deletions and Can Also Reverse Nicks at Ribonucleotide Sites

(2015) Shar-yin Naomi Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ribonucleotides in DNA: hidden in plain sight

(2015) Sue Jinks-Robertson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular underpinnings of Aprataxin RNA/DNA deadenylase function and dysfunction in neurological disease

(2015) Matthew J. Schellenberg et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Ribonucleotides in DNA: hidden in plain sight

(2015) Sue Jinks-Robertson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribonucleotides in DNA: Origins, repair and consequences

(2014) Jessica S. Williams et al.   DNA REPAIR

Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms

(2014) Catherine J. Potenski et al.   NATURE

Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast

(2013) Jang-Eun Cho et al.   DNA REPAIR

Role of Saw1 in Rad1/Rad10 complex assembly at recombination intermediates in budding yeast

(2013) Fuyang Li et al.   EMBO JOURNAL

Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA

(2013) Jessica S. Williams et al.   MOLECULAR CELL

Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration

(2013) Marenda A. Wilson et al.   NATURE

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress

(2013) J. Willis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of RNA 2′,3′-cyclic phosphate end healing by T4 polynucleotide kinase–phosphatase

(2012) Ushati Das et al.   NUCLEIC ACIDS RESEARCH

Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ɛ

(2011) Alan B. Clark et al.   DNA REPAIR

Apurinic/Apyrimidinic Endonuclease 2 Is Necessary for Normal B Cell Development and Recovery of Lymphoid Progenitors after Chemotherapeutic Challenge

(2011) J. E. J. Guikema et al.   JOURNAL OF IMMUNOLOGY

Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I

(2011) N. Kim et al.   SCIENCE

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae

(2010) Hengyao Niu et al.   NATURE

Genome instability due to ribonucleotide incorporation into DNA

(2010) Stephanie A Nick McElhinny et al.   Nature Chemical Biology

MRE11 Function in Response to Topoisomerase Poisons Is Independent of its Function in Double-Strand Break Repair in Saccharomyces cerevisiae

(2010) Nicolle K. Hamilton et al.   PLoS One

Nucleic acid-mediated inflammatory diseases

(2008) Rachel E. Rigby et al.   BIOESSAYS