Structural and molecular basis for Ebola virus neutralization by protective human antibodies

Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1

(2016) Han Wang et al.   CELL

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

(2016) D. Corti et al.   SCIENCE

Structural Basis for Marburg Virus Neutralization by a Cross-Reactive Human Antibody

(2015) Takao Hashiguchi et al.   CELL

Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus

(2015) Andrew I. Flyak et al.   CELL

Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage

(2015) Xueming Li et al.   JOURNAL OF STRUCTURAL BIOLOGY

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

(2015) Jeong Hyun Lee et al.   Nature Communications

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

(2015) Morgan S. A. Gilman et al.   PLoS Pathogens

Camouflage and Misdirection: The Full-On Assault of Ebola Virus Disease

(2014) John Misasi et al.   CELL

Conserved Neutralizing Epitope at Globular Head of Hemagglutinin in H3N2 Influenza Viruses

(2014) Y. Iba et al.   JOURNAL OF VIROLOGY

Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains

(2014) D. Fera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of protective antibodies reveal sites of vulnerability on Ebola virus

(2014) Charles D. Murin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Comparison of the Inhibition Mechanisms of Adalimumab and Infliximab in Treating Tumor Necrosis Factor α-Associated Diseases from a Molecular View

(2013) Shi Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Antibody against the C-Terminal Domain of PCSK9 Lowers LDL Cholesterol Levels In Vivo

(2013) Felix Schiele et al.   JOURNAL OF MOLECULAR BIOLOGY

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Filoviruses Require Endosomal Cysteine Proteases for Entry but Exhibit Distinct Protease Preferences

(2012) J. Misasi et al.   JOURNAL OF VIROLOGY

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cathepsin Cleavage Potentiates the Ebola Virus Glycoprotein To Undergo a Subsequent Fusion-Relevant Conformational Change

(2011) M. Brecher et al.   JOURNAL OF VIROLOGY

Structure of an Antibody in Complex with Its Mucin Domain Linear Epitope That Is Protective against Ebola Virus

(2011) D. Olal et al.   JOURNAL OF VIROLOGY

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

Biochemical and Structural Characterization of Cathepsin L-Processed Ebola Virus Glycoprotein: Implications for Viral Entry and Immunogenicity

(2010) C. L. Hood et al.   JOURNAL OF VIROLOGY

Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms

(2010) Devon J. Shedlock et al.   VIROLOGY

The Primed Ebolavirus Glycoprotein (19-Kilodalton GP1,2): Sequence and Residues Critical for Host Cell Binding

(2009) D. Dube et al.   JOURNAL OF VIROLOGY

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

(2008) Jeffrey E. Lee et al.   NATURE

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complex of a Protective Antibody with Its Ebola Virus GP Peptide Epitope: Unusual Features of a Vλx Light Chain

(2007) Jeffrey E. Lee et al.   JOURNAL OF MOLECULAR BIOLOGY