Mechanical cues modulate cellular uptake of nanoparticles in cancer via clathrin-mediated and caveolae-mediated endocytosis pathways

Physical oncology: New targets for nanomedicine

(2018) Alba Nicolas-Boluda et al.   BIOMATERIALS

SnapShot: Mechanosensing Matrix

(2016) Jerome Irianto et al.   CELL

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

(2016) Hanane Laklai et al.   NATURE MEDICINE

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis

(2016) Huaping Chen et al.   Nature Communications

Porphine functionalized nanoparticles of star-shaped poly(ε-caprolactone)- b -D-α-tocopheryl polyethylene glycol 1000 succinate biodegradable copolymer for chemophotodynamic therapy on cervical cancer

(2015) Wei Cao et al.   Acta Biomaterialia

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Cell and nanoparticle transport in tumour microvasculature: the role of size, shape and surface functionality of nanoparticles

(2015) Ying Li et al.   Interface Focus

Insights into Cellular Uptake of Nanoparticles

(2015) Morteza Kafshgari et al.   Current Drug Delivery

Insight into nanoparticle cellular uptake and intracellular targeting

(2014) Basit Yameen et al.   JOURNAL OF CONTROLLED RELEASE

Comparison of Strain and Shear Wave Elastography for the Differentiation of Benign From Malignant Breast Lesions, Combined With B-mode Ultrasonography: Qualitative and Quantitative Assessments

(2014) Ji Hyun Youk et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Substrate Stiffness Regulates Cellular Uptake of Nanoparticles

(2013) Changjin Huang et al.   NANO LETTERS

Matrix Stiffness in Three-Dimensional Systems Effects on the Behavior of C3A Cells

(2012) Xiaobo Huang et al.   ARTIFICIAL ORGANS

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

(2010) Jörg Schrader et al.   HEPATOLOGY

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology