Cell and nanoparticle transport in tumour microvasculature: the role of size, shape and surface functionality of nanoparticles

Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell–Nanoparticle Interaction

(2015) Lu Zhang et al.   ACS Nano

Remodeling Tumor Vasculature to Enhance Delivery of Intermediate-Sized Nanoparticles

(2015) Wen Jiang et al.   ACS Nano

Physical Principles of Nanoparticle Cellular Endocytosis

(2015) Sulin Zhang et al.   ACS Nano

Enhancement of Endothelial Cell Retention on ePTFE Vascular Constructs by siRNA-Mediated SHP-1 or SHP-2 Gene Silencing

(2015) Brandon J. Tefft et al.   Cellular and Molecular Bioengineering

Nanoparticle–blood interactions: the implications on solid tumour targeting

(2015) James Lazarovits et al.   CHEMICAL COMMUNICATIONS

Nanoparticle hardness controls the internalization pathway for drug delivery

(2015) Ye Li et al.   Nanoscale

Shape effect in cellular uptake of PEGylated nanoparticles: comparison between sphere, rod, cube and disk

(2015) Ying Li et al.   Nanoscale

Microparticle shape effects on margination, near-wall dynamics and adhesion in a three-dimensional simulation of red blood cell suspension

(2015) Koohyar Vahidkhah et al.   Soft Matter

Tunable Rigidity of (Polymeric Core)-(Lipid Shell) Nanoparticles for Regulated Cellular Uptake

(2014) Jiashu Sun et al.   ADVANCED MATERIALS

Endocytosis of PEGylated nanoparticles accompanied by structural and free energy changes of the grafted polyethylene glycol

(2014) Ying Li et al.   BIOMATERIALS

USNCTAM perspectives on mechanics in medicine

(2014) G. Bao et al.   Journal of the Royal Society Interface

Theoretical and Computational Investigations of Nanoparticle-Biomembrane Interactions in Cellular Delivery

(2014) Hong-ming Ding et al.   Small

From Stealthy Polymersomes and Filomicelles to “Self” Peptide-Nanoparticles for Cancer Therapy

(2014) Núria Sancho Oltra et al.   Annual Review of Chemical and Biomolecular Engineering

Quantifying uncertainties in the microvascular transport of nanoparticles

(2013) Tae-Rin Lee et al.   Biomechanics and Modeling in Mechanobiology

Multiscale modeling and uncertainty quantification in nanoparticle-mediated drug/gene delivery

(2013) Ying Li et al.   COMPUTATIONAL MECHANICS

Deep Penetration of Nanoparticulate Drug Delivery Systems into Tumors: Challenges and Solutions

(2013) L. Li et al.   CURRENT MEDICINAL CHEMISTRY

Nanotoxicological classification system (NCS) – A guide for the risk-benefit assessment of nanoparticulate drug delivery systems

(2013) Cornelia M. Keck et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Pharmaceutical Development and Regulatory Considerations for Nanoparticles and Nanoparticulate Drug Delivery Systems

(2013) Ajits. Narang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Margination Propensity of Vascular-Targeted Spheres from Blood Flow in a Microfluidic Model of Human Microvessels

(2013) Katawut Namdee et al.   LANGMUIR

Role of Nanoparticle Geometry in Endocytosis: Laying Down to Stand Up

(2013) Changjin Huang et al.   NANO LETTERS

On the near-wall accumulation of injectable particles in the microcirculation: smaller is not better

(2013) Tae-Rin Lee et al.   Scientific Reports

Systemic and Biophase Bioavailability and Pharmacokinetics of Nanoparticulate Drug Delivery Systems

(2013) Sorin Emilian Leucuta   Current Drug Delivery

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Molecular modeling of the relationship between nanoparticle shape anisotropy and endocytosis kinetics

(2012) Ye Li et al.   BIOMATERIALS

Immersed molecular electrokinetic finite element method

(2012) Adrian M. Kopacz et al.   COMPUTATIONAL MECHANICS

The immersed molecular finite element method

(2012) Adrian M. Kopacz et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

The influence of size, shape and vessel geometry on nanoparticle distribution

(2012) Jifu Tan et al.   Microfluidics and Nanofluidics

Nanoscale sensor analysis using the immersed molecular electrokinetic finite element method

(2012) Adrian M. Kopacz et al.   Nanoscale

Dielectrophoretic concentration of low-abundance nanoparticles using a nanostructured tip

(2012) Woon-Hong Yeo et al.   NANOTECHNOLOGY

Margination of White Blood Cells in Microcapillary Flow

(2012) Dmitry A. Fedosov et al.   PHYSICAL REVIEW LETTERS

Mechanism of Margination in Confined Flows of Blood and Other Multicomponent Suspensions

(2012) Amit Kumar et al.   PHYSICAL REVIEW LETTERS

Selectivity of Ligand-Receptor Interactions between Nanoparticle and Cell Surfaces

(2012) Shihu Wang et al.   PHYSICAL REVIEW LETTERS

Margination and segregation in confined flows of blood and other multicomponent suspensions

(2012) Amit Kumar et al.   Soft Matter

Quantifying the Coverage Density of Poly(ethylene glycol) Chains on the Surface of Gold Nanostructures

(2011) Xiaohu Xia et al.   ACS Nano

Layer-by-Layer Nanoparticles with a pH-Sheddable Layer for in Vivo Targeting of Tumor Hypoxia

(2011) Zhiyong Poon et al.   ACS Nano

Multivalent Binding of Nanocarrier to Endothelial Cells under Shear Flow

(2011) Jin Liu et al.   BIOPHYSICAL JOURNAL

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

(2011) Carl D. Walkey et al.   CHEMICAL SOCIETY REVIEWS

Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution

(2011) Anne L. van de Ven et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The effects of particle size, density and shape on margination of nanoparticles in microcirculation

(2011) Randall Toy et al.   NANOTECHNOLOGY

Cell entry of one-dimensional nanomaterials occurs by tip recognition and rotation

(2011) Xinghua Shi et al.   Nature Nanotechnology

Segregation by membrane rigidity in flowing binary suspensions of elastic capsules

(2011) Amit Kumar et al.   PHYSICAL REVIEW E

Cellular Uptake of Elastic Nanoparticles

(2011) Xin Yi et al.   PHYSICAL REVIEW LETTERS

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

(2011) T. J. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of red blood cells on nanoparticle targeted delivery in microcirculation

(2011) Jifu Tan et al.   Soft Matter

A Reexamination of Active and Passive Tumor Targeting by Using Rod-Shaped Gold Nanocrystals and Covalently Conjugated Peptide Ligands

(2010) Xiaohua Huang et al.   ACS Nano

Nanoparticle Design Optimization for Enhanced Targeting: Monte Carlo Simulations

(2010) Shihu Wang et al.   BIOMACROMOLECULES

Flow and adhesion of drug carriers in blood vessels depend on their shape: A study using model synthetic microvascular networks

(2010) Nishit Doshi et al.   JOURNAL OF CONTROLLED RELEASE

Understanding and overcoming major barriers in cancer nanomedicine

(2010) Shuming Nie   Nanomedicine

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Computational model for nanocarrier binding to endothelium validated using in vivo, in vitro, and atomic force microscopy experiments

(2010) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers

(2009) Phapanin Charoenphol et al.   BIOMATERIALS

Mediating Tumor Targeting Efficiency of Nanoparticles Through Design

(2009) Steven D. Perrault et al.   NANO LETTERS

Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows

(2009) Sei-Young Lee et al.   NANOTECHNOLOGY

Design considerations for tumour-targeted nanoparticles

(2009) Hak Soo Choi et al.   Nature Nanotechnology

Size-Dependent Endocytosis of Nanoparticles

(2008) Sulin Zhang et al.   ADVANCED MATERIALS

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

The Receptor-Mediated Endocytosis of Nonspherical Particles

(2008) P. Decuzzi et al.   BIOPHYSICAL JOURNAL

Therapeutic Nanoparticles for Drug Delivery in Cancer

(2008) K. Cho et al.   CLINICAL CANCER RESEARCH

Simulation and prediction of endothelial cell adhesion modulated by molecular engineering

(2008) Adrian Marcin Kopacz et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

Characterizing left atrial appendage functions in sinus rhythm and atrial fibrillation using computational models

(2008) Lucy T. Zhang et al.   JOURNAL OF BIOMECHANICS

The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows

(2008) F. Gentile et al.   JOURNAL OF BIOMECHANICS

On computational issues of immersed finite element methods

(2008) X. Sheldon Wang et al.   JOURNAL OF COMPUTATIONAL PHYSICS

Recent progress in tumor pH targeting nanotechnology

(2008) Eun Seong Lee et al.   JOURNAL OF CONTROLLED RELEASE

Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications

(2008) Ennio Tasciotti et al.   Nature Nanotechnology

Intravascular Delivery of Particulate Systems: Does Geometry Really Matter?

(2008) Paolo Decuzzi et al.   PHARMACEUTICAL RESEARCH

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manipulation of nanoparticles and biomolecules by electric field and surface tension

(2007) Yaling Liu et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING