The plasmid‐borne quinolone resistance protein QnrB, a novel DnaA‐binding protein, increases the bacterial mutation rate by triggering DNA replication stress

Plasmid persistence: costs, benefits, and the plasmid paradox

(2018) Amanda C. Carroll et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Analysis of the presence of erroneous Qnr sequences in GenBank

(2018) Joaquim Ruiz   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

DNA gyrase activity regulates DnaA-dependent replication initiation in Bacillus subtilis

(2018) A. N. Samadpour et al.   MOLECULAR MICROBIOLOGY

Origin recognition is the predominant role for DnaA-ATP in initiation of chromosome replication

(2018) Julia E Grimwade et al.   NUCLEIC ACIDS RESEARCH

The DnaA Tale

(2018) Flemming G. Hansen et al.   Frontiers in Microbiology

Impact of plasmid interactions with the chromosome and other plasmids on the spread of antibiotic resistance

(2018) João Alves Gama et al.   PLASMID

Emergence of Global Antibiotic Resistance

(2018) Martha Shawn Morehead et al.   PRIMARY CARE

Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context

(2018) Alvaro San Millan   TRENDS IN MICROBIOLOGY

Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli

(2017) Yukari Sakiyama et al.   NUCLEIC ACIDS RESEARCH

The DnaA Cycle in Escherichia coli: Activation, Function and Inactivation of the Initiator Protein

(2017) Tsutomu Katayama et al.   Frontiers in Microbiology

Compensatory mutations improve general permissiveness to antibiotic resistance plasmids

(2017) Wesley Loftie-Eaton et al.   Nature Ecology & Evolution

Too much to handle — how gaining chromosomes destabilizes the genome

(2016) Verena Passerini et al.   CELL CYCLE

Plasmid-mediated quinolone resistance: Two decades on

(2016) José Manuel Rodríguez-Martínez et al.   DRUG RESISTANCE UPDATES

The bacterial DnaA-trio replication origin element specifies single-stranded DNA initiator binding

(2016) Tomas T. Richardson et al.   NATURE

Clonal evolution of glioblastoma under therapy

(2016) Jiguang Wang et al.   NATURE GENETICS

Klebsiella pneumoniae NdpA suppresses ERK pathway-mediated host early inflammatory responses and is degraded through the ubiquitin-proteasome pathway

(2016) Guanghua Xu et al.   Protein & Cell

Mechanisms of drug resistance: quinolone resistance

(2015) David C. Hooper et al.   Annals of the New York Academy of Sciences

Mutations That Enhance the Ciprofloxacin Resistance of Escherichia coli withqnrA1

(2015) Laura Vinué et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tackling antibiotic resistance: the environmental framework

(2015) Thomas U. Berendonk et al.   NATURE REVIEWS MICROBIOLOGY

Targeting DnaN for tuberculosis therapy using novel griselimycins

(2015) A. Kling et al.   SCIENCE

The orisome: structure and function

(2015) Alan C. Leonard et al.   Frontiers in Microbiology

Squaring up to DNA: pentapeptide repeat proteins and DNA mimicry

(2014) Shama Shah et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

DNA Mimic Proteins: Functions, Structures, and Bioinformatic Analysis

(2014) Hao-Ching Wang et al.   BIOCHEMISTRY

Antibiotic-Induced Replication Stress Triggers Bacterial Competence by Increasing Gene Dosage near the Origin

(2014) Jelle Slager et al.   CELL

DNA Replication and Oncogene-Induced Replicative Stress

(2014) Stephanie A. Hills et al.   CURRENT BIOLOGY

Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success

(2014) Liam S. Redgrave et al.   TRENDS IN MICROBIOLOGY

Mutation rate plasticity in rifampicin resistance depends on Escherichia coli cell–cell interactions

(2014) Rok Krašovec et al.   Nature Communications

Phylogenetic Analysis of Chromosomally Determined Qnr and Related Proteins

(2013) George A. Jacoby et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Direct Detection of Antibody Concentration and Affinity in Human Serum Using Microscale Thermophoresis

(2012) Svenja Lippok et al.   ANALYTICAL CHEMISTRY

Label-Free Microscale Thermophoresis Discriminates Sites and Affinity of Protein-Ligand Binding

(2012) Susanne A. I. Seidel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Differentiation of the DnaA-oriCSubcomplex for DNA Unwinding in a Replication Initiation Complex

(2012) Shogo Ozaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Topological characterization of the DnaA–oriC complex using single-molecule nanomanipuation

(2012) Sylvain Zorman et al.   NUCLEIC ACIDS RESEARCH

Mycobacterium fluoroquinolone resistance protein B, a novel small GTPase, is involved in the regulation of DNA gyrase and drug resistance

(2012) Jun Tao et al.   NUCLEIC ACIDS RESEARCH

SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler

(2012) Ruibang Luo et al.   GigaScience

Replication initiation at the Escherichia coli chromosomal origin

(2011) Jon M Kaguni   CURRENT OPINION IN CHEMICAL BIOLOGY

Bacterial hypermutation: clinical implications

(2011) A. Jolivet-Gougeon et al.   JOURNAL OF MEDICAL MICROBIOLOGY

DNA stretching by bacterial initiators promotes replication origin opening

(2011) Karl E. Duderstadt et al.   NATURE

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

(2011) Erdal Toprak et al.   NATURE GENETICS

Highly organized DnaA– oriC complexes recruit the single-stranded DNA for replication initiation

(2011) Shogo Ozaki et al.   NUCLEIC ACIDS RESEARCH

Adaptation and Evolutionary Rescue in Metapopulations Experiencing Environmental Deterioration

(2011) G. Bell et al.   SCIENCE

Complete Nucleotide Sequence of Klebsiella pneumoniae Multidrug Resistance Plasmid pKP048, Carrying blaKPC-2, blaDHA-1, qnrB4, and armA

(2010) Y. Jiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

(2010) Michael A. Kohanski et al.   MOLECULAR CELL

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

Role of RecA and the SOS Response in Thymineless Death in Escherichia coli

(2010) Natalie C. Fonville et al.   PLoS Genetics

Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis

(2009) B. M. Hall et al.   BIOINFORMATICS

The SOS response promotes qnrB quinolone-resistance determinant expression

(2009) Sandra Da Re et al.   EMBO REPORTS

DnaAcos hyperinitiates by circumventing regulatory pathways that control the frequency of initiation inEscherichia coli

(2009) Magdalena M. Felczak et al.   MOLECULAR MICROBIOLOGY

SOS Regulation of qnrB Expression

(2008) M. Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The RAST Server: Rapid Annotations using Subsystems Technology

(2008) Ramy K Aziz et al.   BMC GENOMICS

Low selection of topoisomerase mutants from strains of Escherichia coli harbouring plasmid-borne qnr genes

(2008) A. Cesaro et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Pentapeptide Repeat Proteins MfpAMt and QnrB4 Exhibit Opposite Effects on DNA Gyrase Catalytic Reactions and on the Ternary Gyrase-DNA-Quinolone Complex

(2008) A. Merens et al.   JOURNAL OF BACTERIOLOGY

A Common Mechanism for the ATP-DnaA-dependent Formation of Open Complexes at the Replication Origin

(2008) Shogo Ozaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY