Inactivation of the quorum-sensing transcriptional regulators LasR or RhlR does not suppress the expression of virulence factors and the virulence of Pseudomonas aeruginosa PAO1

Pseudomonas aeruginosatranscriptome during human infection

(2018) Daniel M. Cornforth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PqsE and RhlR proteins are an autoinducer synthase–receptor pair that control virulence and biofilm development in Pseudomonas aeruginosa

(2018) Sampriti Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Mouse Model for Chronic Infections by Gram-Negative Bacteria Enabling the Study of Anti-Infective Efficacy and Host-Microbe Interactions

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The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer

(2017) Sampriti Mukherjee et al.   PLoS Pathogens

LasR Variant Cystic Fibrosis Isolates Reveal an Adaptable Quorum-Sensing Hierarchy in Pseudomonas aeruginosa

(2016) John B. Feltner et al.   mBio

Do Bacterial “Virulence Factors” Always Increase Virulence? A Meta-Analysis of Pyoverdine Production in Pseudomonas aeruginosa As a Test Case

(2016) Elisa T. Granato et al.   Frontiers in Microbiology

Is Quorum Sensing Interference a Viable Alternative to Treat Pseudomonas aeruginosa Infections?

(2016) Rodolfo García-Contreras   Frontiers in Microbiology

Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control inPseudomonas aeruginosa

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Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD

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High variability in quorum quenching and growth inhibition by furanone C-30 inPseudomonas aeruginosaclinical isolates from cystic fibrosis patients

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A Drug-Repositioning Screening Identifies Pentetic Acid as a Potential Therapeutic Agent for Suppressing the Elastase-Mediated Virulence of Pseudomonas aeruginosa

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Coordination of Swarming Motility, Biosurfactant Synthesis, and Biofilm Matrix Exopolysaccharide Production in Pseudomonas aeruginosa

(2014) Shiwei Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

siRNA-mediated gene silencing of MexB from the MexA-MexB-OprM efflux pump in Pseudomonas aeruginosa

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Pseudomonas aeruginosa clinical and environmental isolates constitute a single population with high phenotypic diversity

(2014) María-Victoria Grosso-Becerra et al.   BMC GENOMICS

QsrO a Novel Regulator of Quorum-Sensing and Virulence in Pseudomonas aeruginosa

(2014) Thilo Köhler et al.   PLoS One

Diversity of Virulence Phenotypes among Type III Secretion Negative Pseudomonas aeruginosa Clinical Isolates

(2014) Jonida Toska et al.   PLoS One

Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa

(2014) Kevin T. O’Brien et al.   ACS Medicinal Chemistry Letters

Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target

(2014) Chien-Yi Chang et al.   Scientific Reports

The hierarchy quorum sensing network in Pseudomonas aeruginosa

(2014) Jasmine Lee et al.   Protein & Cell

Targeting quorum sensing inPseudomonas aeruginosabiofilms: current and emerging inhibitors

(2013) Tim Holm Jakobsen et al.   Future Microbiology

A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

(2013) C. T. O'Loughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

(2013) Shaan L. Gellatly et al.   Pathogens and Disease

The Pseudomonas aeruginosa Reference Strain PA14 Displays Increased Virulence Due to a Mutation in ladS

(2011) Helga Mikkelsen et al.   PLoS One

Engineering Artificial Small RNAs for Conditional Gene Silencing in Escherichia coli

(2011) Vandana Sharma et al.   ACS Synthetic Biology

Quorum Sensing Inhibition Selects for Virulence and Cooperation in Pseudomonas aeruginosa

(2010) Thilo Köhler et al.   PLoS Pathogens

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

(2009) Paul Williams et al.   CURRENT OPINION IN MICROBIOLOGY

Covalent Inhibition of Bacterial Quorum Sensing

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