Challenges and tackles in metabolic engineering for microbial production of carotenoids

Apocarotenoids: Emerging Roles in Mammals

(2018) Earl H. Harrison et al.   Annual Review of Nutrition

Advances in synthetic biology of oleaginous yeast Yarrowia lipolytica for producing non-native chemicals

(2018) Farshad Darvishi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

cis -carotene biosynthesis, evolution and regulation in plants: The emergence of novel signaling metabolites

(2018) Yagiz Alagoz et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Carotenoids in human nutrition and health

(2018) Manfred Eggersdorfer et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Coproduction of cell-bound and secreted value-added compounds: Simultaneous production of carotenoids and amino acids by Corynebacterium glutamicum

(2018) Nadja A. Henke et al.   BIORESOURCE TECHNOLOGY

Toward industrial production of isoprenoids in Escherichia coli : Lessons learned from CRISPR-Cas9 based optimization of a chromosomally integrated mevalonate pathway

(2018) Jorge Alonso-Gutierrez et al.   BIOTECHNOLOGY AND BIOENGINEERING

CRISPR-Enabled Tools for Engineering Microbial Genomes and Phenotypes

(2018) Katia Tarasava et al.   Biotechnology Journal

Metabolic Redesign of Rhodobacter sphaeroides for Lycopene Production

(2018) Anping Su et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dietary Carotenoid Roles in Redox Homeostasis and Human Health

(2018) Marcelo P. Barros et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Selected Methods of Extracting Carotenoids, Characterization, and Health Concerns: A Review

(2018) Parise Adadi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health

(2018) Manuel Rodriguez-Concepcion et al.   PROGRESS IN LIPID RESEARCH

In vitro DNA SCRaMbLE

(2018) Yi Wu et al.   Nature Communications

CRISPR-Enabled Tools for Engineering Microbial Genomes and Phenotypes

(2018) Katia Tarasava et al.   Biotechnology Journal

Recent advances in metabolic engineering of Corynebacterium glutamicum for bioproduction of value-added aromatic chemicals and natural products

(2018) Takahisa Kogure et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Astaxanthin overproduction in yeast by strain engineering and new gene target uncovering

(2018) Jin Jin et al.   Biotechnology for Biofuels

Antioxidant and pro-oxidant activities of carotenoids and their oxidation products

(2018) Daniela Ribeiro et al.   FOOD AND CHEMICAL TOXICOLOGY

Metabolic engineering of Escherichia coli for high-level astaxanthin production with high productivity

(2018) Seon Young Park et al.   METABOLIC ENGINEERING

Efficient production of lycopene in Saccharomyces cerevisiae by enzyme engineering and increasing membrane flexibility and NAPDH production

(2018) Juhyun Hong et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Optimizing the localization of astaxanthin enzymes for improved productivity

(2018) Lijun Ye et al.   Biotechnology for Biofuels

Development of Xanthophyllomyces dendrorhous as a production system for the colorless carotene phytoene

(2017) Hendrik Pollmann et al.   JOURNAL OF BIOTECHNOLOGY

Iterative integration of multiple-copy pathway genes in Yarrowia lipolytica for heterologous β-carotene production

(2017) Shuliang Gao et al.   METABOLIC ENGINEERING

Balanced activation of IspG and IspH to eliminate MEP intermediate accumulation and improve isoprenoids production in Escherichia coli

(2017) Qingyan Li et al.   METABOLIC ENGINEERING

Engineering microbial cell factories for the production of plant natural products: from design principles to industrial-scale production

(2017) Xiaonan Liu et al.   Microbial Cell Factories

The Impact of Systems Biology on Bioprocessing

(2017) Kate Campbell et al.   TRENDS IN BIOTECHNOLOGY

Automated multiplex genome-scale engineering in yeast

(2017) Tong Si et al.   Nature Communications

Carotenoids Database: structures, chemical fingerprints and distribution among organisms

(2017) Junko Yabuzaki   Database-The Journal of Biological Databases and Curation

Host and Pathway Engineering for Enhanced Lycopene Biosynthesis in Yarrowia lipolytica

(2017) Cory Schwartz et al.   Frontiers in Microbiology

Isoprenoid Pyrophosphate-Dependent Transcriptional Regulation of Carotenogenesis in Corynebacterium glutamicum

(2017) Nadja A. Henke et al.   Frontiers in Microbiology

Scale translation from shaken to diffused bubble aerated systems for lycopene production by Blakeslea trispora under stimulated conditions

(2016) Fani Th Mantzouridou et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering of the carotenoid pathway in Xanthophyllomyces dendrorhous leading to the synthesis of zeaxanthin

(2016) Hendrik Pollmann et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Waste cooking oil: A new substrate for carotene production by Blakeslea trispora in submerged fermentation

(2016) Konstantina Nanou et al.   BIORESOURCE TECHNOLOGY

The potential of the mevalonate pathway for enhanced isoprenoid production

(2016) Pan Liao et al.   BIOTECHNOLOGY ADVANCES

EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes intoSaccharomyces cerevisiaevia CRISPR-Cas9

(2016) Mathew M Jessop-Fabre et al.   Biotechnology Journal

Developing fermentative terpenoid production for commercial usage

(2016) Michael D Leavell et al.   CURRENT OPINION IN BIOTECHNOLOGY

Enhancement of astaxanthin production in Xanthophyllomyces dendrorhous by efficient method for the complete deletion of genes

(2016) Keisuke Yamamoto et al.   Microbial Cell Factories

Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering

(2016) Yan Chen et al.   Microbial Cell Factories

Rewriting yeast central carbon metabolism for industrial isoprenoid production

(2016) Adam L. Meadows et al.   NATURE

Integrating Networks and Proteomics: Moving Forward

(2016) Wilson Wen Bin Goh et al.   TRENDS IN BIOTECHNOLOGY

The Need for Integrated Approaches in Metabolic Engineering

(2016) Anna Lechner et al.   Cold Spring Harbor Perspectives in Biology

Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica

(2016) Cory Schwartz et al.   ACS Synthetic Biology

Direct Combinatorial Pathway Optimization

(2016) Pieter Coussement et al.   ACS Synthetic Biology

EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes intoSaccharomyces cerevisiaevia CRISPR-Cas9

(2016) Mathew M Jessop-Fabre et al.   Biotechnology Journal

A comprehensive review on the colorless carotenoids phytoene and phytofluene

(2015) Antonio J. Meléndez-Martínez et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Assembly of functional photosystem complexes in Rhodobacter sphaeroides incorporating carotenoids from the spirilloxanthin pathway

(2015) Shuang C. Chi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Selective retinol production by modulating the composition of retinoids from metabolically engineeredE. coli

(2015) Hui-Jeong Jang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic engineering of Yarrowia lipolytica for industrial applications

(2015) Quinn Zhu et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metabolic engineering of Escherichia coli using CRISPR–Cas9 meditated genome editing

(2015) Yifan Li et al.   METABOLIC ENGINEERING

A highly selective biosynthetic pathway to non-natural C50 carotenoids assembled from moderately selective enzymes

(2015) Maiko Furubayashi et al.   Nature Communications

Evaluation and screening of efficient promoters to improve astaxanthin production in Xanthophyllomyces dendrorhous

(2014) Kiyotaka Y. Hara et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic engineering for the microbial production of carotenoids and related products with a focus on the rare C50 carotenoids

(2014) Sabine A. E. Heider et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Plant carotenoids: genomics meets multi-gene engineering

(2014) Giovanni Giuliano   CURRENT OPINION IN PLANT BIOLOGY

Biotechnological production of carotenoids by yeasts: an overview

(2014) Luis Mata-Gómez et al.   Microbial Cell Factories

Production of Lycopene in the Non-Carotenoid-Producing Yeast Yarrowia lipolytica

(2013) Falk Matthäus et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Engineering central metabolic modules of Escherichia coli for improving β-carotene production

(2013) Jing Zhao et al.   METABOLIC ENGINEERING

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

(2013) Wenyan Jiang et al.   NATURE BIOTECHNOLOGY

On the Structure and Function of the Phytoene Desaturase CRTI from Pantoea ananatis, a Membrane-Peripheral and FAD-Dependent Oxidase/Isomerase

(2012) Patrick Schaub et al.   PLoS One

Nutritional Aspects of Phytoene and Phytofluene, Carotenoid Precursors to Lycopene

(2012) Nancy J. Engelmann et al.   Advances in Nutrition

Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system

(2011) Hui-Jeong Jang et al.   Microbial Cell Factories

Combinatorial expression of bacterial whole mevalonate pathway for the production of β-carotene in E. coli

(2009) Sang-Hwal Yoon et al.   JOURNAL OF BIOTECHNOLOGY

Programming cells by multiplex genome engineering and accelerated evolution

(2009) Harris H. Wang et al.   NATURE

Stabilized gene duplication enables long-term selection-free heterologous pathway expression

(2009) Keith E J Tyo et al.   NATURE BIOTECHNOLOGY

Evolution of carotene desaturation: The complication of a simple pathway

(2008) Gerhard Sandmann   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS