Article
Medicine, General & Internal
Felix Teufel, Jacqueline A. Seiglie, Pascal Geldsetzer, Michaela Theilmann, Maja E. Marcus, Cara Ebert, William Andres Lopez Arboleda, Kokou Agoudavi, Glennis Andall-Brereton, Krishna K. Aryal, Brice Wilfried Bicaba, Garry Brian, Pascal Bovet, Maria Dorobantu, Mongal Singh Gurung, David Guwatudde, Corine Houehanou, Dismand Houinato, Jutta M. Adelin Jorgensen, Gibson B. Kagaruki, Khem B. Karki, Demetre Labadarios, Joao S. Martins, Mary T. Mayige, Roy Wong McClure, Joseph Kibachio Mwangi, Omar Mwalim, Bolormaa Norov, Sarah Crooks, Farshad Farzadfar, Sahar Saeedi Moghaddam, Bahendeka K. Silver, Lela Sturua, Chea Stanford Wesseh, Andrew C. Stokes, Utibe R. Essien, Jan-Walter De Neve, Rifat Atun, Justine I. Davies, Sebastian Vollmer, Till W. Barnighausen, Mohammed K. Ali, James B. Meigs, Deborah J. Wexler, Jennifer Manne-Goehler
Summary: The prevalence of overweight, obesity, and diabetes is increasing rapidly in low-income and middle-income countries, with BMI affecting the risk of diabetes, but there are significant regional variations in this association.
Article
Endocrinology & Metabolism
Rui Zhou, Furong Li, Guochong Chen, Qiang Fu, Shanyuan Gu, Xianbo Wu
Summary: This study found that both general and abdominal obesity were associated with an increased risk of incident diabetic neuropathy among individuals with type 2 diabetes mellitus, regardless of sex.
JOURNAL OF DIABETES
(2021)
Article
Nutrition & Dietetics
Kyoung-Yun Kim, Ha-Rin Moon, Jung-Mi Yun
Summary: Metabolic syndrome is a complex disorder associated with high risks of type 2 diabetes and cardiovascular disease. This study utilized KNHANES data to investigate neck circumference as a predictor for MetS risk, with findings demonstrating a significant association between neck circumference and MetS risk, suggesting the need for further research for validation.
Article
Endocrinology & Metabolism
Xiao-cong Liu, Yu Huang, Kenneth Lo, Yu-qing Huang, Ji-yan Chen, Ying-qing Feng
Summary: The study found that the Waist-BMI Ratio can independently predict overall and cardiovascular mortality risk in a dose-response relationship, with ROC curve analysis showing it to be a better discriminator of mortality compared to BMI, WC, and waist-to-height ratio.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Gastroenterology & Hepatology
Eun Hyo Jin, Kyungdo Han, Dong Ho Lee, Cheol Min Shin, Joo Hyun Lim, Yoon Jin Choi, Kichul Yoon
Summary: The study found that obesity and metabolic syndrome are associated with an increased risk of earlier-onset colorectal cancer, particularly left-sided colon cancer. Individuals with metabolic syndrome and obesity have a higher risk of developing colorectal cancer before the age of 50, highlighting the importance of preventive interventions for this population.
Article
Public, Environmental & Occupational Health
Azra Ramezankhani, Fereidoun Azizi, Mitra Hasheminia, Farzad Hadaegh
Summary: This study examined the association between obesity indices and hospitalization rates in Iranian adults. Obese individuals and those with high waist circumference had higher rates of hospitalization, particularly in women, suggesting that obesity prevention programs may reduce hospitalizations.
Article
Nutrition & Dietetics
Victor M. Oguoma, Neil T. Coffee, Saad Alsharrah, Mohamed Abu-Farha, Faisal H. Al-Refaei, Abdullah Alkandari, Fahd Al-Mulla, Mark Daniel
Summary: This study aimed to determine anthropometric cut-points for screening diabetes and the metabolic syndrome (MetS) in Arab and South Asian ethnic groups in Kuwait. The study found that the anthropometric cut-points for diabetes and cardiovascular disease risk factors were higher in Arab men, while South Asian women had higher cut-points. Additionally, the International Diabetes Federation's cut-points led to a higher prevalence of the MetS.
BRITISH JOURNAL OF NUTRITION
(2022)
Review
Nutrition & Dietetics
Felipe Mendes Delpino, Lilian Munhoz Figueiredo
Summary: Melatonin supplementation may significantly reduce body weight, but its effects on BMI and waist circumference are inconclusive, requiring further studies for confirmation.
Article
Multidisciplinary Sciences
Kadari Cisse, Delwende Rene Severin Samadoulougou, Joel Dofinissery Bognini, Tiga David Kangoye, Fati Kirakoya-Samadoulougou
Summary: This study in Burkina Faso aimed to determine the prevalence of metabolic syndrome and its determinants among the adult population. The prevalence of metabolic syndrome varied according to different definitions, with higher rates among those living in urban areas and older individuals.
Article
Endocrinology & Metabolism
Guotai Sheng, Jiajun Qiu, Maobin Kuang, Nan Peng, Guobo Xie, Yuanqin Chen, Shuhua Zhang, Yang Zou
Summary: This study aimed to evaluate and compare the predictive value of three simple anthropometric indicators of obesity (BMI, WC, and WHtR) for the occurrence of diabetes in the future. The results showed that WC was the best indicator, and WHtR performed best for predicting diabetes in the medium to long term.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Mesut Savas, Vincent L. Wester, Bibian van der Voorn, Anand M. Iyer, Jan W. Koper, Erica L. T. van den Akker, Elisabeth F. C. van Rossum
Summary: This study found that genetic polymorphisms associated with increased glucocorticoid receptor (GR) sensitivity were related to higher risks of obesity, increased waist circumference, and metabolic syndrome compared to individuals with normal GR genes. Furthermore, this association was more pronounced in users of inhaled corticosteroids.
NEUROENDOCRINOLOGY
(2021)
Article
Nutrition & Dietetics
Jose Ignacio Ramirez-Manent, Andres Martinez Jover, Caroline Silveira Martinez, Pilar Tomas-Gil, Pau Marti-Lliteras, Angel Arturo Lopez-Gonzalez
Summary: Metabolic syndrome (Met-S) is a significant health problem associated with insulin resistance (IR). This study aims to assess the relationship between different insulin resistance risk scales and Met-S and identify the components of Met-S that contribute most to IR. The results demonstrate that insulin resistance risk scales can accurately classify individuals with Met-S, particularly when using the International Diabetes Federation (IDF) criteria, and waist circumference is the key factor associated with both IR and Met-S.
Article
Biochemistry & Molecular Biology
Yu-Lin Shih, Chin-Chuan Shih, Tzu-Cheng Huang, Jau-Yuan Chen
Summary: This study investigated the relationship between homocysteine levels and metabolic syndrome. The results showed that the metabolic syndrome group had higher homocysteine levels, and participants with higher homocysteine levels were more likely to have metabolic syndrome.
Article
Nutrition & Dietetics
Klarissa R. Wilkinson, Larry A. Tucker, Lance E. Davidson, Bruce W. Bailey
Summary: Regular consumption of non-fat milk was associated with lower levels of abdominal adiposity, while no significant differences were found for full-fat milk drinkers or milk abstainers.
Article
Health Care Sciences & Services
Marco La Marra, Antonietta Messina, Ciro Rosario Ilardi, Giuseppe Verde, Raffaella Amato, Nadia Esposito, Simona Troise, Antonella Orlando, Giovanni Messina, Vincenzo Monda, Girolamo Di Maio, Ines Villano
Summary: This study suggests that waist circumference is a better indicator of the association between obesity and executive functions compared to body mass index. Furthermore, it found that motor performance partially mediates this relationship.
Article
Cardiac & Cardiovascular Systems
Zahra Raisi-Estabragh, Ofer Kobo, Phillip Freeman, Steffen E. Petersen, Louis Kolman, Robert J. H. Miller, Ariel Roguin, Harriette G. C. Van Spall, Jacqueline Vuong, Eric H. Yang, Mamas A. Mamas
Summary: This study reports disease-specific cardiovascular causes of mortality among cancer patients in the USA between 1999 and 2019, considering temporal trends by age, sex, and cancer site. Ischaemic heart disease was the most common cardiovascular cause of death across all cancer types, followed by cerebrovascular disease and hypertensive diseases. Differential cardiovascular mortality risk was observed based on cancer site and demographics.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2023)
Article
Cardiac & Cardiovascular Systems
Ofer Kobo, Majdi Saada, Clemens von Birgelen, Pim A. L. Tonino, Andres Iniguez-Romo, Ole Frobert, Majdi Halabi, Rohit M. Oemrawsingh, Jawed Polad, Alexander J. J. IJsselmuiden, Marco Roffi, Adel Aminian, Mamas A. Mamas, Ariel Roguin
Summary: Patients with previously known vascular disease have an increased risk of adverse cardiovascular events and mortality after percutaneous coronary intervention (PCI), with the highest risk among patients with multisite artery disease.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2023)
Article
Medicine, General & Internal
Ofer Kobo, Saadiq M. Moledina, Mohamed O. Mohamed, Aynharan Sinnarajah, Jessica Simon, Louise Y. Sun, Michael Slawnych, David L. Fischman, Ariel Roguin, Mamas A. Mamas
Summary: This study aimed to examine the predictors, treatments, and outcomes of palliative care use in acute myocardial infarction (AMI) patients with a do-not-resuscitate (DNR) order. The study found that only one-third of DNR patients received palliative care, and these patients were younger, more likely to experience cardiac arrest, received fewer invasive treatments, and had a higher in-hospital mortality rate.
MAYO CLINIC PROCEEDINGS
(2023)
Article
Cardiac & Cardiovascular Systems
Ofer Kobo, Dmitry Abramov, Marat Fudim, Garima Sharma, Vijay Bang, Ashish Deshpande, Rishi K. Wadhera, Mamas A. Mamas
Summary: Cardiovascular mortality increased by 4.6% in the United States in 2020 compared to 2019, with the highest increases observed among adults under 55 and Black and Hispanic populations. There was an increase in deaths from ischaemic heart disease, hypertensive disease, and cerebrovascular disease, but a decline in heart failure mortality.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2023)
Article
Cardiac & Cardiovascular Systems
Dmitry Abramov, Ofer Kobo, Eiran Z. Gorodeski, Jamal S. Rana, Mary Norine Walsh, Purvi Parwani, Phyo K. Myint, Andrew J. Sauer, Mamas A. Mamas
Summary: Acute heart failure (AHF) is a common cause of hospitalization and is associated with complications such as bleeding. This study aimed to assess the incidence, types, and factors associated with major bleeding in patients hospitalized with AHF. The study found that 5.3% of AHF patients experienced major bleeding, with common sources being gastrointestinal, hematuria, respiratory, and procedure-related bleeding. Major bleeding was associated with higher inpatient mortality, longer length of stay, and higher costs.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Erick Sanchez-Jimenez, Rami Abu Fanne, Yaniv Levi, Majdi Saada, Ofer Kobo, Ariel Roguin
Summary: Despite effective epicardial coronary recanalization, mechanical complications after acute myocardial infarction (AMI) are associated with high mortality, especially in cardiogenic shock patients. The use of mechanical circulatory support has increased in patients with cardiogenic shock and mechanical complications, but evidence is scarce and most studies exclude patients with mechanical complications.
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2023)
Article
Urology & Nephrology
Ofer Kobo, Dmitry Abramov, Simon Davies, Sofia B. Ahmed, Louise Y. Sun, Jennifer H. Mieres, Purvi Parwani, Zbigniew Siudak, Harriette G. C. Van Spall, Mamas A. Mamas
Summary: Between 1999 and 2020, there was a slight decrease in cardiovascular-related mortality among patients with chronic kidney disease (CKD) in the United States, while non-cardiovascular-related mortality showed a significant increase. Black patients had consistently higher cardiovascular mortality rates, while Hispanic patients had a greater reduction in cardiovascular mortality.
Article
Cardiac & Cardiovascular Systems
Majeed Zahalka, Erick Sanchez-Jimenez, Yaniv Levi, Rami Abu-Fanne, Majdi Saada, Eli Israel Lev, Majdi Halabi, Simcha Ron Meisel, Ariel Roguin, Ofer Kobo
Summary: A newly developed bedside model has been validated in a study conducted in Israel to predict in-hospital, 30-day, and 1-year mortality in patients with acute ischemia. This model has a wider scope of application compared with previous ones and includes high-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Gemina Doolub, Mario Iannaccone, Tanveer Rab, Helen Routledge, Adel Aminian, Bernard Chevalier, David Hildick-Smith, Lotte Jacobs, Ofer Kobo, Ariel Roguin, Alaide Chieffo, Mamas A. A. Mamas
Summary: This study aimed to assess whether there are differences between women and men in strategy and outcomes of bifurcation PCI. The results showed that women and men had similar stent strategy choices and treatment outcomes at 1-year follow-up, regardless of the type of bifurcation lesions.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Hussein Bashar, Ofer Kobo, Kamlesh Khunti, Amitava Banerjee, Renee P. Bullock-Palmer, Nick Curzen, Mamas A. Mamas
Summary: The study finds a correlation between social vulnerability and mortality from diabetes-related cardiovascular diseases. Counties with higher social vulnerability have higher mortality rates, especially among younger adults.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Gilad Margolis, Nashed Hamuda, Ofer Kobo, Gabby Elbaz Greener, Offer Amir, Munther Homoud, Christopher Madias, Edwin Kevin Heist, Jeremy N. Ruskin, Mark Kazatsker, Ariel Roguin, Eran Leshem, Guy Rozen
Summary: The addition of an atrial lead during ICD implantation for primary prevention of sudden cardiac death was not shown to be beneficial. This study found that dual-chamber ICD implantation in patients without pacing indications is associated with higher complication rates.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Hussein Bashar, Ofer Kobo, Kamlesh Khunti, Louise Y. Sun, Martin K. Rutter, Nicholas W. S. Chew, Nick Curzen, Mamas A. Mamas
Summary: In the past few decades, diabetes-related cardiovascular mortality has been declining, but the COVID-19 pandemic caused a significant increase in mortality in the first year. Younger patients and the Black population experienced the greatest increase in mortality.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Michael Kleiner Shochat, Jameel Mohsen, Elias Hellou, Ofer Kobo, Simcha Meisel
JOURNAL OF CARDIAC FAILURE
(2023)
Letter
Urology & Nephrology
Dmitry Abramov, Ofer Kobo, Simon Davies, Roy O. Mathew, Harriette G. C. Van Spall, Mamas A. Mamas
JOURNAL OF NEPHROLOGY
(2023)
Article
Peripheral Vascular Disease
Zahra Raisi-Estabragh, Ofer Kobo, Teresa Lopez-Fernandez, Husam Abdel Qadir, Nicholas W. S. Chew, Wojtek Wojakowski, Abhishek Abhishek, Robert J. H. Miller, Mamas A. Mamas
Summary: This study examined social disparities in cardiovascular mortality of people with and without cancer in the US population between 1999 and 2019. It found that cardiovascular mortality rate was higher in men, rural settings, and Black or African American races. Over time, there was a decline in cardiovascular mortality rate, with a greater reduction in those with cancer. Sex, race, and ethnic disparities reduced in the cancer cohort, but urban-rural disparities increased.
INTERNATIONAL JOURNAL OF CARDIOLOGY CARDIOVASCULAR RISK AND PREVENTION
(2023)
