Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo

Alamandine acts via MrgD to induce AMPK/NO activation against ANG II hypertrophy in cardiomyocytes

(2018) Itamar Couto Guedes de Jesus et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Angiotensin-(1–7) and Alamandine on Experimental Models of Hypertension and Atherosclerosis

(2018) Fernando Pedro de Souza-Neto et al.   CURRENT HYPERTENSION REPORTS

Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation

(2018) Kikuo Isoda et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Alamandine attenuates sepsis-associated cardiac dysfunction via inhibiting MAPKs signaling pathways

(2018) Peng Li et al.   LIFE SCIENCES

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation

(2018) John A. Marwick et al.   Cell Death & Disease

Genetic deletion of the alamandine receptor MRGD leads to dilated cardiomyopathy in mice

(2018) Aline Cristina Oliveira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

(2017) Analina R. Da Silva et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Angiotensin-(1–7) administration attenuates Alzheimer’s disease-like neuropathology in rats with streptozotocin-induced diabetes via Mas receptor activation

(2017) Jin-Liang Chen et al.   NEUROSCIENCE

Angiotensin-(1-7) Promotes Resolution of Neutrophilic Inflammation in a Model of Antigen-Induced Arthritis in Mice

(2017) Lívia C. Barroso et al.   Frontiers in Immunology

Temporal changes in cardiac oxidative stress, inflammation and remodeling induced by exercise in hypertension: Role for local angiotensin II reduction

(2017) Sebastião D. Silva et al.   PLoS One

Contribution of Macrophage Polarization to Metabolic Diseases

(2016) Yoshihiro Komohara et al.   Journal of Atherosclerosis and Thrombosis

Proresolving Actions of Synthetic and Natural Protease Inhibitors Are Mediated by Annexin A1

(2016) Juliana P. Vago et al.   JOURNAL OF IMMUNOLOGY

Role of the receptor Mas in macrophage-mediated inflammation in vivo

(2016) Anna Hammer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Angiotensin-(1-7)/Mas Axis Counteracts Angiotensin II-Dependent and -Independent Pro-inflammatory Signaling in Human Vascular Smooth Muscle Cells

(2016) Laura A. Villalobos et al.   Frontiers in Pharmacology

Resolution of Inflammation: What Controls Its Onset?

(2016) Michelle A. Sugimoto et al.   Frontiers in Immunology

Angiotensin-(1-7) attenuates airway remodelling and hyperresponsiveness in a model of chronic allergic lung inflammation

(2015) G S Magalhães et al.   BRITISH JOURNAL OF PHARMACOLOGY

Human monocyte subsets exhibit divergent angiotensin I-converting activity

(2015) M. Rutkowska-Zapała et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Role and Effects of Glucocorticoid-Induced Leucine Zipper in the Context of Inflammation Resolution

(2015) Juliana P. Vago et al.   JOURNAL OF IMMUNOLOGY

Angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis prevents lipopolysaccharide–induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF–κB pathways

(2015) Yingchuan Li et al.   Scientific Reports

Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro

(2015) Zikun Huang et al.   PLoS One

Diverse macrophage populations mediate acute lung inflammation and resolution

(2014) Neil R. Aggarwal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation

(2014) Matilde Alique et al.   CLINICAL SCIENCE

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Macrophage Polarization in Inflammatory Diseases

(2014) Yan-Cun Liu et al.   International Journal of Biological Sciences

Reduction of angiotensin A and alamandine vasoactivity in the rabbit model of atherogenesis: differential effects of alamandine and Ang(1-7)

(2014) Belthrand Habiyakare et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Plasmin Induces In Vivo Monocyte Recruitment through Protease-Activated Receptor-1–, MEK/ERK-, and CCR2-Mediated Signaling

(2014) Aline A. F. Carmo et al.   JOURNAL OF IMMUNOLOGY

Receptor Mas Protects Mice Against Hypothermia and Mortality Induced By Endotoxemia

(2014) Laura L. Souza et al.   SHOCK

Treatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaques

(2014) Silvia Savergnini et al.   THROMBOSIS AND HAEMOSTASIS

Discovery and Characterization of Alamandine

(2013) Roberto Queiroga Lautner et al.   CIRCULATION RESEARCH

Changes in macrophage phenotype as the immune response evolves

(2013) Julia Lichtnekert et al.   CURRENT OPINION IN PHARMACOLOGY

Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke

(2013) Robert W. Regenhardt et al.   NEUROPHARMACOLOGY

An orally active angiotensin-(1–7) inclusion compound and exercise training produce similar cardiovascular effects in spontaneously hypertensive rats

(2013) Mariane Bertagnolli et al.   PEPTIDES

Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis

(2012) Juliana P. Vago et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation

(2012) Amiram Ariel et al.   Frontiers in Immunology

Transcriptomic analyses of murine resolution-phase macrophages

(2011) M. J. Stables et al.   BLOOD

Angiotensin-(1-7) decreases LPS-induced inflammatory response in macrophages

(2011) Laura L. Souza et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A new look at the renin–angiotensin system—Focusing on the vascular system

(2011) Aurelie Nguyen Dinh Cat et al.   PEPTIDES

Macrophage Polarization in Health and Disease

(2011) Luca Cassetta et al.   TheScientificWorldJOURNAL

Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

(2010) Merlin C. Thomas et al.   CIRCULATION RESEARCH

Saturated-efferocytosis generates pro-resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids

(2010) Sagie Schif-Zuck et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Angiotensin-converting enzyme is required for normal myelopoiesis

(2010) Chentao Lin et al.   FASEB JOURNAL

Anti-Inflammatory Effects of the Activation of the Angiotensin-(1-7) Receptor, Mas, in Experimental Models of Arthritis

(2010) K. D. da Silveira et al.   JOURNAL OF IMMUNOLOGY

PDE4 inhibition drives resolution of neutrophilic inflammation by inducing apoptosis in a PKA-PI3K/Akt-dependent and NF-κB-independent manner

(2010) Lirlândia P. Sousa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-κB

(2009) Lirlândia P. Sousa et al.   BIOCHEMICAL PHARMACOLOGY

Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1β release through pyrophosphates

(2009) Pablo Pelegrin et al.   EMBO JOURNAL

Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP

(2008) J. Bystrom et al.   BLOOD

Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-α

(2008) Sylwia Michlewska et al.   FASEB JOURNAL

Angiotensin-(1–7) enhances angiotensin II induced phosphorylation of ERK1/2 in mouse bone marrow-derived dendritic cells

(2008) Wencheng Nie et al.   MOLECULAR IMMUNOLOGY