The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone

Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator

(2018) Fredrik Erlandsson et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

(2018) Krister Bamberg et al.   PLoS One

Third-generation Mineralocorticoid Receptor Antagonists

(2016) Elise P. Gomez-Sanchez   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Nonsteroidal antagonists of the mineralocorticoid receptor

(2015) Peter Kolkhof et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

CS-3150, a novel non-steroidal mineralocorticoid receptor antagonist, prevents hypertension and cardiorenal injury in Dahl salt-sensitive hypertensive rats

(2015) Kiyoshi Arai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy

(2015) George L. Bakris et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

(2012) Lars Bärfacker et al.   ChemMedChem

SM-368229, a Novel Selective and Potent Non-steroidal Mineralocorticoid Receptor Antagonist With Strong Urinary Na+ Excretion Activity

(2011) Tetsuro Nariai et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism

(2011) Rena J Eudy et al.   Journal of Translational Medicine

Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease

(2011) Jean-Philippe Bertocchio et al.   KIDNEY INTERNATIONAL

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

(2010) Faiez Zannad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of a simplified assay for determination of the antimineralocorticoid activity of compounds dosed in rats

(2008) Philip E. Brandish et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS