Pathogenesis of age-related HIV neurodegeneration

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

(2018) John L Robinson et al.   BRAIN

Aging and Apolipoprotein E in HIV Infection

(2018) Rebeca Geffin et al.   JOURNAL OF NEUROVIROLOGY

Review: Vascular dementia: clinicopathologic and genetic considerations

(2018) H. V. Vinters et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The Aging Brain With HIV Infection: Effects of Alcoholism or Hepatitis C Comorbidity

(2018) Natalie M. Zahr   Frontiers in Aging Neuroscience

Heavy Alcohol Use and Age Effects on HIV‐Associated Neurocognitive Function

(2018) Ronald A. Cohen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Adult Hippocampal Neurogenesis: A Coming-of-Age Story

(2018) H. Georg Kuhn et al.   JOURNAL OF NEUROSCIENCE

Correction to: Aging and apolipoprotein E in HIV infection

(2018) Rebeca Geffin et al.   JOURNAL OF NEUROVIROLOGY

White matter damage, neuroinflammation, and neuronal integrity in HAND

(2018) Aljoharah Alakkas et al.   JOURNAL OF NEUROVIROLOGY

Early Introduction of cART Reverses Brain Aging Pattern in Well-Controlled HIV Infection: A Comparative MR Spectroscopy Study

(2018) Jasmina M. Boban et al.   Frontiers in Aging Neuroscience

Biomarkers of neuronal injury and amyloid metabolism in the cerebrospinal fluid of patients infected with HIV-1 subtypes B and C

(2017) Sérgio Monteiro de Almeida et al.   JOURNAL OF NEUROVIROLOGY

The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration

(2017) Jerel A. Fields et al.   JOURNAL OF NEUROVIROLOGY

HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity

(2017) Alina Hategan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Increased brain-predicted aging in treated HIV disease

(2017) James H. Cole et al.   NEUROLOGY

HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration

(2017) Qingqing Chai et al.   Nature Communications

HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity

(2017) Alina Hategan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Differentiating HIV-Associated Neurocognitive Disorders From Alzheimer’s Disease: an Emerging Issue in Geriatric NeuroHIV

(2017) Benedetta Milanini et al.   Current HIV/AIDS Reports

TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia

(2016) Bryan D. James et al.   BRAIN

Lower CSF A? is Associated with HAND in HIV-Infected Adults with a Family History of Dementia

(2016) Pariya. L. Fazeli et al.   CURRENT HIV RESEARCH

ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60

(2016) Lauren A. Wendelken et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

HIV Tat Impairs Neurogenesis through Functioning As a Notch Ligand and Activation of Notch Signaling Pathway

(2016) Y. Fan et al.   JOURNAL OF NEUROSCIENCE

The Emergence of Geroscience as an Interdisciplinary Approach to the Enhancement of Health Span and Life Span

(2016) Felipe Sierra   Cold Spring Harbor Perspectives in Medicine

APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals – a cross-sectional observational study

(2015) Lucette A Cysique et al.   BMC Neurology

Impaired neurogenesis by HIV-1-Gp120 is rescued by genetic deletion of fatty acid amide hydrolase enzyme

(2015) H K Avraham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of HIV-1 Tat Neurotoxicity via CDK5 Translocation and Hyper-Activation: Role in HIV-Associated Neurocognitive Disorders

(2015) Jerel Fields et al.   CURRENT HIV RESEARCH

HIV-1 Tat Alters Neuronal Autophagy by Modulating Autophagosome Fusion to the Lysosome: Implications for HIV-Associated Neurocognitive Disorders

(2015) J. Fields et al.   JOURNAL OF NEUROSCIENCE

Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders

(2015) Andrew J. Levine et al.   JOURNAL OF NEUROVIROLOGY

Age exacerbates HIV-associated white matter abnormalities

(2015) Talia R. Seider et al.   JOURNAL OF NEUROVIROLOGY

Immunotherapeutic Approaches Targeting Amyloid-β, α-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders

(2015) Elvira Valera et al.   Neurotherapeutics

Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration

(2015) Grant R. Campbell et al.   PLoS Pathogens

The cerebrospinal fluid biomarker profile in an HIV-infected subject with Alzheimer’s disease

(2015) Signar Mäkitalo et al.   AIDS Research and Therapy

Differential clinicopathologic and genetic features of late-onset amnestic dementias

(2014) Melissa E. Murray et al.   ACTA NEUROPATHOLOGICA

HIV protease inhibitor exposure predicts cerebral small vessel disease

(2014) Virawudh Soontornniyomkij et al.   AIDS

Decreased neuronal autophagy in HIV dementia: A mechanism of indirect neurotoxicity

(2014) Mehrdad Alirezaei et al.   Autophagy

Autophagy: An overlooked mechanism of HIV-1 pathogenesis and NeuroAIDS?

(2014) Stephen A. Spector et al.   Autophagy

Convergence of pathology in dementia with Lewy bodies and Alzheimer’s disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease

(2014) Ashley R. Winslow et al.   BRAIN

Geroscience: Linking Aging to Chronic Disease

(2014) Brian K. Kennedy et al.   CELL

The impact of HIV-1 on neurogenesis: implications for HAND

(2014) Darren Ferrell et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of Neurotrophic Factor Alterations in the Neurodegenerative Process in HIV Associated Neurocognitive Disorders

(2014) Jerel Fields et al.   Journal of Neuroimmune Pharmacology

The role of tau protein in HIV-associated neurocognitive disorders

(2014) Lecia AM Brown et al.   Molecular Neurodegeneration

The clinical characteristics of dementia with Lewy bodies and a consideration of prodromal diagnosis

(2014) Paul C Donaghy et al.   Alzheimers Research & Therapy

Contents

(2013)   Alzheimers & Dementia

Inhibition of human immunodeficiency virus type-1 through autophagy

(2013) Grant R Campbell et al.   CURRENT OPINION IN MICROBIOLOGY

Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer

(2013) Jerel Fields et al.   JOURNAL OF NEUROVIROLOGY

Molecular and pathologic insights from latent HIV-1 infection in the human brain

(2013) P. Desplats et al.   NEUROLOGY

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census

(2013) L. E. Hebert et al.   NEUROLOGY

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia

(2013) T. Zu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

(2013) T. P. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frontotemporal Dementia: Implications for Understanding Alzheimer Disease

(2013) M. Goedert et al.   Cold Spring Harbor Perspectives in Medicine

Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers

(2012) Virawudh Soontornniyomkij et al.   AIDS

11C-PiB Imaging of Human Immunodeficiency Virus–Associated Neurocognitive Disorder

(2012) Beau M. Ances   ARCHIVES OF NEUROLOGY

Synergistic Effects of HIV Infection and Older Age on Daily Functioning

(2012) Erin E. Morgan et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Platelet-Derived Growth Factor-BB Restores Human Immunodeficiency Virus Tat-Cocaine-Mediated Impairment of Neurogenesis: Role of TRPC1 Channels

(2012) H. Yao et al.   JOURNAL OF NEUROSCIENCE

Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine

(2011) Christina Patrick et al.   AMERICAN JOURNAL OF PATHOLOGY

FTD and ALS: A Tale of Two Diseases

(2011) R. Ferrari et al.   Current Alzheimer Research

Autophagy Is Increased in Postmortem Brains of Persons With HIV-1-Associated Encephalitis

(2011) Dejiang Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

Distinct Roles In Vivo for the Ubiquitin-Proteasome System and the Autophagy-Lysosomal Pathway in the Degradation of  -Synuclein

(2011) D. Ebrahimi-Fakhari et al.   JOURNAL OF NEUROSCIENCE

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

(2011) Patrice Codogno et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Beclin 1 Complex in Autophagy and Alzheimer Disease

(2010) Philipp A. Jaeger et al.   ARCHIVES OF NEUROLOGY

Molecular mechanisms of neurodegeneration in Alzheimer's disease

(2010) L. Crews et al.   HUMAN MOLECULAR GENETICS

Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy

(2010) I Everall et al.   JOURNAL OF NEUROVIROLOGY

Does highly active antiretroviral therapy improve neurocognitive function? A systematic review

(2010) John A Joska et al.   JOURNAL OF NEUROVIROLOGY

Human immunodeficiency virus type 1 Tat modulates proliferation and differentiation of human neural precursor cells: implication in NeuroAIDS

(2010) Mamata Mishra et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy

(2010) Leslie Crews et al.   PLoS One

Phosphorylated TDP-43 in Alzheimer’s disease and dementia with Lewy bodies

(2009) Tetsuaki Arai et al.   ACTA NEUROPATHOLOGICA

Persistent Hijacking of Brain Proteasomes in HIV-Associated Dementia

(2009) Trung P. Nguyen et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular Pathology of Neuro-AIDS (CNS-HIV)

(2009) Leslie Crews et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

HIV Regulation of Amyloid Beta Production

(2009) Lynn Pulliam   Journal of Neuroimmune Pharmacology

Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients

(2009) Cristian L. Achim et al.   Journal of Neuroimmune Pharmacology

Increased frequency of α-synuclein in the substantia nigra in human immunodeficiency virus infection

(2009) Negar Khanlou et al.   JOURNAL OF NEUROVIROLOGY

The Comorbidity of HIV-Associated Neurocognitive Disorders and Alzheimer’s Disease: A Foreseeable Medical Challenge in Post-HAART Era

(2008) Jiqing Xu et al.   Journal of Neuroimmune Pharmacology

Disruption of Neuronal Autophagy by Infected Microglia Results in Neurodegeneration

(2008) Mehrdad Alirezaei et al.   PLoS One

HIV-1 Tat Activates Neuronal Ryanodine Receptors with Rapid Induction of the Unfolded Protein Response and Mitochondrial Hyperpolarization

(2008) John P. Norman et al.   PLoS One

Chemokine receptors and neurotrophic factors: Potential therapy against aids dementia?

(2007) Italo Mocchetti et al.   JOURNAL OF NEUROSCIENCE RESEARCH