A comprehensive review of therapeutic targets that induce microglia/macrophage-mediated hematoma resolution after germinal matrix hemorrhage

Chemerin suppresses neuroinflammation and improves neurological recovery via CaMKK2/AMPK/Nrf2 pathway after germinal matrix hemorrhage in neonatal rats

(2018) Yixin Zhang et al.   BRAIN BEHAVIOR AND IMMUNITY

Hematoma clearance as a therapeutic target in intracerebral hemorrhage: From macro to micro

(2018) D Andrew Wilkinson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Bliverdin reductase-A improves neurological function in a germinal matrix hemorrhage rat model

(2018) Yiting Zhang et al.   NEUROBIOLOGY OF DISEASE

Microglia and Neonatal Brain Injury

(2018) Carina Mallard et al.   NEUROSCIENCE

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke

(2017) Masato Kanazawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modulators of microglial activation and polarization after intracerebral haemorrhage

(2017) Xi Lan et al.   Nature Reviews Neurology

Alternative activation-skewed microglia/macrophages promote hematoma resolution in experimental intracerebral hemorrhage

(2017) Che-Feng Chang et al.   NEUROBIOLOGY OF DISEASE

Simvastatin Promotes Hematoma Absorption and Reduces Hydrocephalus Following Intraventricular Hemorrhage in Part by Upregulating CD36

(2017) Qianwei Chen et al.   Translational Stroke Research

CD163, a Hemoglobin/Haptoglobin Scavenger Receptor, After Intracerebral Hemorrhage: Functions in Microglia/Macrophages Versus Neurons

(2017) Thomas Garton et al.   Translational Stroke Research

Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice

(2016) Moon-Sook Woo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cilostazol ameliorates collagenase-induced cerebral hemorrhage by protecting the blood–brain barrier

(2016) Toshinori Takagi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

PPARγ-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats

(2016) Jerry J. Flores et al.   NEUROBIOLOGY OF DISEASE

Hematoma Changes During Clot Resolution After Experimental Intracerebral Hemorrhage

(2016) Shenglong Cao et al.   STROKE

Role of Erythrocyte CD47 in Intracerebral Hematoma Clearance

(2016) Wei Ni et al.   STROKE

CD36 regulates lipopolysaccharide-induced signaling pathways and mediates the internalization of Escherichia coli in cooperation with TLR4 in goat mammary gland epithelial cells

(2016) Duoyao Cao et al.   Scientific Reports

Modulating the Immune Response Towards a Neuroregenerative Peri-injury Milieu After Cerebral Hemorrhage

(2015) Damon Klebe et al.   Journal of Neuroimmune Pharmacology

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

Minocycline Attenuates Neonatal Germinal-Matrix-Hemorrhage-Induced Neuroinflammation and Brain Edema by Activating Cannabinoid Receptor 2

(2015) Jun Tang et al.   MOLECULAR NEUROBIOLOGY

Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage

(2015) Loretta O. Iniaghe et al.   NEUROBIOLOGY OF DISEASE

Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children

(2015) Elizabeth Newell et al.   Pediatric Critical Care Medicine

Dimethyl Fumarate Protects Brain From Damage Produced by Intracerebral Hemorrhage by Mechanism Involving Nrf2

(2015) Xiurong Zhao et al.   STROKE

Pharmacological Preventions of Brain Injury Following Experimental Germinal Matrix Hemorrhage: an Up-to-Date Review

(2015) Jun Tang et al.   Translational Stroke Research

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro

(2015) Melanie S. Brennan et al.   PLoS One

The role of TLR2, TLR4 and CD36 in macrophage activation and foam cell formation in response to oxLDL in humans

(2014) Luis Chávez-Sánchez et al.   HUMAN IMMUNOLOGY

Cleaning up after ICH: the role of Nrf2 in modulating microglia function and hematoma clearance

(2014) Xiurong Zhao et al.   JOURNAL OF NEUROCHEMISTRY

Role of Hemoglobin and Iron in Hydrocephalus After Neonatal Intraventricular Hemorrhage

(2014) Jennifer M. Strahle et al.   NEUROSURGERY

Acute and Delayed Deferoxamine Treatment Attenuates Long-Term Sequelae After Germinal Matrix Hemorrhage in Neonatal Rats

(2014) Damon Klebe et al.   STROKE

Pathogenesis and Prevention of Intraventricular Hemorrhage

(2013) Praveen Ballabh   CLINICS IN PERINATOLOGY

Effects of Monascin on Anti-inflammation Mediated by Nrf2 Activation in Advanced Glycation End Product-Treated THP-1 Monocytes and Methylglyoxal-Treated Wistar Rats

(2013) Bao-Hong Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hydrocephalus in 389 patients with aneurysm-associated subarachnoid hemorrhage

(2013) Christoph M. Woernle et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Microglia: Key Elements in Neural Development, Plasticity, and Pathology

(2013) Ukpong B. Eyo et al.   Journal of Neuroimmune Pharmacology

The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging

(2013) Jens Haugbølle Thomsen et al.   Oxidative Medicine and Cellular Longevity

Molecular Modeling of the Human Hemoglobin-Haptoglobin Complex Sheds Light on the Protective Mechanisms of Haptoglobin

(2013) Chanin Nantasenamat et al.   PLoS One

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration

(2013) V. Hugh Perry et al.   Seminars in Immunopathology

A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia

(2013) Wei-Hsuan Hsu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair

(2013) Anat London et al.   Frontiers in Cellular Neuroscience

Deferoxamine Reduces Neuronal Death and Hematoma Lysis After Intracerebral Hemorrhage in Aged Rats

(2013) Tetsuhiro Hatakeyama et al.   Translational Stroke Research

Genetic deletion of CD36 enhances injury after acute neonatal stroke

(2012) Moon-Sook Woo et al.   ANNALS OF NEUROLOGY

Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo

(2012) Bao-Hong Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Design of a Prospective, Dose-Escalation Study Evaluating the Safety of Pioglitazone for Hematoma Resolution in Intracerebral Hemorrhage (SHRINC)

(2012) Nicole R. Gonzales et al.   International Journal of Stroke

Microglia activation in the extremely preterm human brain

(2012) Veena Supramaniam et al.   PEDIATRIC RESEARCH

Microglia/Macrophage-Derived Inflammatory Mediators Galectin-3 and Quinolinic Acid are Elevated in Cerebrospinal Fluid from Newborn Infants After Birth Asphyxia

(2012) Karin Sävman et al.   Translational Stroke Research

Mechanisms of Hydrocephalus After Neonatal and Adult Intraventricular Hemorrhage

(2012) Jennifer Strahle et al.   Translational Stroke Research

Beginnings of a Good Apoptotic Meal: The Find-Me and Eat-Me Signaling Pathways

(2011) Kodi S. Ravichandran   IMMUNITY

Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke

(2011) J. V. Faustino et al.   JOURNAL OF NEUROSCIENCE

Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits

(2011) Bryna Erblich et al.   PLoS One

Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase

(2011) B. Wegiel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid treatment skews human monocyte differentiation into a hemoglobin-clearance phenotype with enhanced heme-iron recycling and antioxidant capacity

(2010) F. Vallelian et al.   BLOOD

Hemoglobin and Iron Handling in Brain after Subarachnoid Hemorrhage and the Effect of Deferoxamine on Early Brain Injury

(2010) Jin-Yul Lee et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Spontaneous Intracerebral Hemorrhage With Ventricular Extension and the Grading of Obstructive Hydrocephalus: The Prediction of Outcome of a Special Life-Threatening Entity

(2010) Marco Stein et al.   NEUROSURGERY

Decreased CD47 expression during spontaneous apoptosis targets neutrophils for phagocytosis by monocyte-derived macrophages

(2009) Donald W. Lawrence et al.   EARLY HUMAN DEVELOPMENT

Neuroprotective Role of Haptoglobin after Intracerebral Hemorrhage

(2009) X. Zhao et al.   JOURNAL OF NEUROSCIENCE

Intraventricular Hemorrhage in Premature Infants: Mechanism of Disease

(2009) Praveen Ballabh   PEDIATRIC RESEARCH

Annual Summary of Vital Statistics: 2007

(2009) M. Heron et al.   PEDIATRICS

Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin

(2009) Jaime Kapitulnik et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Hematoma Resolution as a Therapeutic Target: The Role of Microglia/Macrophages

(2008) X. Zhao et al.   STROKE