Nutrient sensor signaling pathways and cellular stress in fetal growth restriction

Pathophysiology of placental-derived fetal growth restriction

(2018) Graham J. Burton et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Oxidative stress in placental pathology

(2018) Mirthe H. Schoots et al.   PLACENTA

Analytical model of the feto-placental vascular system: consideration of placental oxygen transport

(2018) Parisa Mirbod   Royal Society Open Science

Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation

(2017) Hai-Bin Ruan et al.   GENES & DEVELOPMENT

SustainedO-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism

(2017) Ee Phie Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trophoblast lineage specification, differentiation and their regulation by oxygen tension

(2017) Ching-Wen Chang et al.   JOURNAL OF ENDOCRINOLOGY

Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth

(2017) Amanda N. Sferruzzi-Perri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Review: Placental mitochondrial function and structure in gestational disorders

(2017) Olivia Holland et al.   PLACENTA

Mammalian target of rapamycin signaling is a mechanistic link between increased endoplasmic reticulum stress and autophagy in the placentas of pregnancies complicated by growth restriction

(2017) Tai-Ho Hung et al.   PLACENTA

Sex-specific differences and developmental programming for diseases in later life

(2017) Deepali P. Sundrani et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease

(2017) Willayat Y. Wani et al.   Molecular Brain

Potential coordination role between O-GlcNAcylation and epigenetics

(2017) Donglu Wu et al.   Protein & Cell

Placental O-GlcNAc-transferase expression and interactions with the glucocorticoid receptor are sex specific and regulated by maternal corticosterone exposure in mice

(2017) Marie Pantaleon et al.   Scientific Reports

Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth

(2016) Fredrick J. Rosario et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The regulatory roles of O-GlcNAcylation in mitochondrial homeostasis and metabolic syndrome

(2016) Lin Zhao et al.   FREE RADICAL RESEARCH

Programming of maternal and offspring disease: impact of growth restriction, fetal sex and transmission across generations

(2016) Jean N. Cheong et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative Stress: Placenta Function and Dysfunction

(2015) Fan Wu et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

You are what you eat

(2015) Stéphanie Olivier-Van Stichelen et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Circulating and myometrial markers of oxidative stress in pregnant women with fetal growth restriction

(2015) Ebru Biberoglu et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Placental phenotype and resource allocation to fetal growth are modified by the timing and degree of hypoxia during mouse pregnancy

(2015) J. S. Higgins et al.   JOURNAL OF PHYSIOLOGY-LONDON

Maternal corticosterone exposure in the mouse causes sex specific alterations in placental OGT and O-linked glycosylation.

(2015) James Cuffe et al.   PLACENTA

O-GlcNAc cycling enzymes control vascular development of the placenta by modulating the levels of HIF-1α

(2015) Yong Ryoul Yang et al.   PLACENTA

Placental Adaptations in Growth Restriction

(2015) Song Zhang et al.   Nutrients

Sex differences in metabolic homeostasis, diabetes, and obesity

(2015) Franck Mauvais-Jarvis   Biology of Sex Differences

Genetic, nongenetic and epigenetic risk determinants in developmental programming of type 2 diabetes

(2014) Allan Vaag et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation

(2014) Stéphan Hardivillé et al.   Cell Metabolism

Mitochondrial DNA in Placenta: Associations with Fetal Growth and Superoxide Dismutase Activity

(2014) Marta Díaz et al.   Hormone Research in Paediatrics

Maternal–Fetal Nutrient Transport in Pregnancy Pathologies: The Role of the Placenta

(2014) Kendra Brett et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrative transcriptome meta-analysis reveals widespread sex-biased gene expression at the human fetal-maternal interface

(2014) S. Buckberry et al.   MOLECULAR HUMAN REPRODUCTION

O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation

(2014) Bin Guo et al.   NATURE CELL BIOLOGY

The Hexosamine Biosynthetic Pathway: A role in nutrient regulation of growth signalling in the human placenta

(2014) Victoria Palin et al.   PLACENTA

Regulation of Human Trophoblast GLUT1 Glucose Transporter by Insulin-Like Growth Factor I (IGF-I)

(2014) Marc U. Baumann et al.   PLoS One

Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction

(2014) Christopher L. Howerton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis

(2013) Jennifer A. Groves et al.   CELL STRESS & CHAPERONES

Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

(2013) Jovita V. Kavitha et al.   FASEB JOURNAL

Effect of fetal and child health on kidney development and long-term risk of hypertension and kidney disease

(2013) Valerie A Luyckx et al.   LANCET

Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

(2013) Francesca Colleoni et al.   PLoS One

O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development

(2013) C. L. Howerton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental origins of diabetes: The role of oxidative stress

(2012) Rebecca A. Simmons   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude

(2012) Hong Wa Yung et al.   FASEB JOURNAL

Newborns of Preeclamptic Women Show Evidence of Sex-Specific Disparity in Fetal Growth

(2012) Simone A. Reynolds et al.   Gender Medicine

Role of oxidative stress in preeclampsia and intrauterine growth restriction

(2012) Ismail Mert et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction

(2012) Hong wa Yung et al.   JOURNAL OF PATHOLOGY

Oxygen delivery and fetal-placental growth: Beyond a question of supply and demand?

(2012) A.J. Murray   PLACENTA

The emerging role of mTORC1 signaling in placental nutrient-sensing

(2012) T. Jansson et al.   PLACENTA

Maternal cortisol disproportionately impacts fetal growth in male offspring: Evidence from the philippines

(2011) Zaneta M. Thayer et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

Placental DEPTOR as a stress sensor during pregnancy

(2011) Dionisis Mparmpakas et al.   CLINICAL SCIENCE

Placental-SpecificIgf2Deficiency Alters Developmental Adaptations to Undernutrition in Mice

(2011) A. N. Sferruzzi-Perri et al.   ENDOCRINOLOGY

Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

(2011) Fredrick J. Rosario et al.   ENDOCRINOLOGY

Full-Length Adiponectin Attenuates Insulin Signaling and Inhibits Insulin-Stimulated Amino Acid Transport in Human Primary Trophoblast Cells

(2010) H. N. Jones et al.   DIABETES

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Consequences of a compromised intrauterine environment on islet function

(2010) Alice S Green et al.   JOURNAL OF ENDOCRINOLOGY

The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth

(2010) A. N. Sferruzzi-Perri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of amino acid transporters by glucose and growth factors in cultured primary human trophoblast cells is mediated by mTOR signaling

(2009) S. Roos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

(2009) John A. Hanover et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Toxic Effects of Hyperglycemia Are Mediated by the Hexosamine Signaling Pathway and O-Linked Glycosylation in Early Mouse Embryos1

(2009) Marie Pantaleon et al.   BIOLOGY OF REPRODUCTION

Serum prolidase activity and oxidative stress markers in pregnancies with intrauterine growth restricted infants

(2009) Harun Toy et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Understanding placental nutrient transfer - why bother? New biomarkers of fetal growth

(2009) C. P. Sibley   JOURNAL OF PHYSIOLOGY-LONDON

Leptin Affects System A Amino Acid Transport Activity in the Human Placenta: Evidence for STAT3 Dependent Mechanisms

(2009) F. von Versen-Höynck et al.   PLACENTA

Evidence of Placental Translation Inhibition and Endoplasmic Reticulum Stress in the Etiology of Human Intrauterine Growth Restriction

(2008) Hong-wa Yung et al.   AMERICAN JOURNAL OF PATHOLOGY

The Mechanisms and Regulation of Placental Amino Acid Transport to the Human Foetus

(2008) J. K. Cleal et al.   JOURNAL OF NEUROENDOCRINOLOGY

The Placenta and Intrauterine Programming

(2008) A. L. Fowden et al.   JOURNAL OF NEUROENDOCRINOLOGY

Nutrient Sensing by the Early Mouse Embryo: Hexosamine Biosynthesis and Glucose Signaling During Preimplantation Development1

(2007) Marie Pantaleon et al.   BIOLOGY OF REPRODUCTION