Milestones and recent discoveries on cell death mediated by mitochondria and their interactions with biologically active amines

The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases

(2016) Matthew Redmann et al.   Aging and Disease

β-Hydroxy-β-methylbutyrate, mitochondrial biogenesis, and skeletal muscle health

(2015) Xi He et al.   AMINO ACIDS

Bioconjugation of gold-polymer core–shell nanoparticles with bovine serum amine oxidase for biomedical applications

(2015) I. Venditti et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A novel enzyme with spermine oxidase properties in bovine liver mitochondria: Identification and kinetic characterization

(2015) Emanuela Bonaiuto et al.   FREE RADICAL BIOLOGY AND MEDICINE

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

(2014) F Pietrocola et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Permeability Transition as Target of Anticancer Drugs

(2014) Lisa Via et al.   CURRENT PHARMACEUTICAL DESIGN

Spermidine-triggered autophagy ameliorates memory during aging

(2013) Stephan J Sigrist et al.   Autophagy

Agmatine: clinical applications after 100 years in translation

(2013) John E. Piletz et al.   DRUG DISCOVERY TODAY

Keeping mitochondria in shape: a matter of life and death

(2013) Luca Scorrano   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Synthetic polyamines activating autophagy: Effects on cancer cell death

(2013) Anna Minarini et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Polyamines and cancer: implications for chemotherapy and chemoprevention

(2013) Shannon L. Nowotarski et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

What is the nature of the mitochondrial permeability transition poreand What is it Not?

(2013) Detlef Siemen et al.   IUBMB LIFE

Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size

(2013) Stephanie Bleicken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronic Acid Nanohydrogels as a Useful Tool for BSAO Immobilization in the Treatment of Melanoma Cancer Cells

(2013) Elita Montanari et al.   MACROMOLECULAR BIOSCIENCE

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular and molecular mechanisms of mitochondrial function

(2012) Laura D. Osellame et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Physiological Roles of the Permeability Transition Pore

(2012) Catherine Brenner et al.   CIRCULATION RESEARCH

Mitochondria and cell signalling

(2012) Stephen W. G. Tait et al.   JOURNAL OF CELL SCIENCE

Further characterization of agmatine binding to mitochondrial membranes: involvement of imidazoline I2 receptor

(2011) Pamela Martinis et al.   AMINO ACIDS

Mitochondrial oxidative stress induced by Ca2+ and monoamines: different behaviour of liver and brain mitochondria in undergoing permeability transition

(2011) Silvia Grancara et al.   AMINO ACIDS

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Effects of exogenous agmatine in human leukemia HMC-1 and HL-60 cells on proliferation, polyamine metabolism and cell cycle

(2011) Britta Haenisch et al.   LEUKEMIA RESEARCH

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Spermidine: A novel autophagy inducer and longevity elixir

(2010) Frank Madeo et al.   Autophagy

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial

(2010) Ory Keynan et al.   PAIN MEDICINE

Polyamines: fundamental characters in chemistry and biology

(2009) E. Agostinelli et al.   AMINO ACIDS

Agmatine prevents the Ca2+-dependent induction of permeability transition in rat brain mitochondria

(2009) V. Battaglia et al.   AMINO ACIDS

Novel copper amine oxidase activity from rat liver mitochondria matrix

(2009) Sara Cardillo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Agmatine protects cultured retinal ganglion cells from tumor necrosis factor-alpha-induced apoptosis

(2008) Samin Hong et al.   LIFE SCIENCES