P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria

Emerging concepts in T follicular helper cell responses to malaria

(2017) Diana S. Hansen et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

ATP-Induced Inflammation Drives Tissue-Resident Th17 Cells in Metabolically Unhealthy Obesity

(2016) Julieta B. Pandolfi et al.   JOURNAL OF IMMUNOLOGY

Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation

(2016) Victoria Ryg-Cornejo et al.   Cell Reports

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection

(2016) Ismail Sebina et al.   PLoS Pathogens

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

(2015) John P. Ray et al.   IMMUNITY

In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria

(2015) Henrique Borges da Silva et al.   PLoS Pathogens

Disruption of IL-21 Signaling Affects T Cell-B Cell Interactions and Abrogates Protective Humoral Immunity to Malaria

(2015) Damián Pérez-Mazliah et al.   PLoS Pathogens

ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism

(2014) Michele Proietti et al.   IMMUNITY

Gradual Decline in Malaria-Specific Memory T Cell Responses Leads to Failure to Maintain Long-Term Protective Immunity to Plasmodium chabaudi AS Despite Persistence of B Cell Memory and Circulating Antibody

(2014) A. P. Freitas do Rosario et al.   JOURNAL OF IMMUNOLOGY

Leukotriene B4 Modulates P2X7 Receptor-Mediated Leishmania amazonensis Elimination in Murine Macrophages

(2014) M. M. Chaves et al.   JOURNAL OF IMMUNOLOGY

Pulmonary Infection with Hypervirulent Mycobacteria Reveals a Crucial Role for the P2X7 Receptor in Aggressive Forms of Tuberculosis

(2014) Eduardo P. Amaral et al.   PLoS Pathogens

IFN- -Induced Priming Maintains Long-Term Strain-Transcending Immunity against Blood-Stage Plasmodium chabaudi Malaria

(2013) H. B. da Silva et al.   JOURNAL OF IMMUNOLOGY

Characterizing the Presence and Sensitivity of the P2X7 Receptor in Different Compartments of the Gut

(2012) Nathalia Enes de Campos et al.   Journal of Innate Immunity

Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells

(2011) Marion Pepper et al.   IMMUNITY

Cell biology and immunology of malaria

(2011) Julius Clemence Hafalla et al.   IMMUNOLOGICAL REVIEWS

IL-27 Promotes IL-10 Production by Effector Th1 CD4+ T Cells: A Critical Mechanism for Protection from Severe Immunopathology during Malaria Infection

(2011) A. P. Freitas do Rosario et al.   JOURNAL OF IMMUNOLOGY

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

(2011) Wei Liao et al.   NATURE IMMUNOLOGY

Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection

(2011) Noah S Butler et al.   NATURE IMMUNOLOGY

The Spleen CD4+ T Cell Response to Blood-Stage Plasmodium chabaudi Malaria Develops in Two Phases Characterized by Different Properties

(2011) Sandra Marcia Muxel et al.   PLoS One

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

(2011) U. Schenk et al.   Science Signaling

Harnessing immune responses against Plasmodium for rational vaccine design

(2011) Bruno Douradinha et al.   TRENDS IN PARASITOLOGY

The contribution of Plasmodium chabaudi to our understanding of malaria

(2011) Robin Stephens et al.   TRENDS IN PARASITOLOGY

Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

(2010) T. Woehrle et al.   BLOOD

Activation of the P2X7 receptor triggers the elimination of Toxoplasma gondii tachyzoites from infected macrophages

(2010) Gladys Corrêa et al.   MICROBES AND INFECTION

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R

(2010) Konrad Wilhelm et al.   NATURE MEDICINE

Purinergic signalling is involved in the malaria parasite Plasmodium falciparum invasion to red blood cells

(2010) Julio Levano-Garcia et al.   Purinergic Signalling

Effector Memory Th1 CD4 T Cells Are Maintained in a Mouse Model of Chronic Malaria

(2010) Robin Stephens et al.   PLoS Pathogens

Autocrine regulation of T-cell activation by ATP release and P2X7 receptors

(2009) Linda Yip et al.   FASEB JOURNAL

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Functional Memory B Cells and Long-Lived Plasma Cells Are Generated after a Single Plasmodium chabaudi Infection in Mice

(2009) Francis Maina Ndungu et al.   PLoS Pathogens

Potential link between the immune system and metabolism of nucleic acids

(2008) Ken J Ishii et al.   CURRENT OPINION IN IMMUNOLOGY

Immunity to malaria: more questions than answers

(2008) Jean Langhorne et al.   NATURE IMMUNOLOGY

The Plasmodium falciparum-induced anion channel of human erythrocytes is an ATP-release pathway

(2008) Canan Akkaya et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

(2008) Patrizia Pellegatti et al.   PLoS One