Article
Environmental Sciences
Fengjun Lei, Ning Zhang, Jingjing Miao, Ruixue Tong, Yaobing Li, Luqing Pan
Summary: This study aims to investigate the effects of benzo(a)pyrene (B[a]P) on the immunity of Chlamys farreri and explore its potential molecular mechanism. Multiple biomarkers were used to assess these effects, and it was found that B[a]P had concentration-dependent immunotoxicity, possibly affecting immunity through the detoxification metabolic system, neuroendocrine system, and cell apoptosis pathway.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Xiaoxue Zhang, Xiaomin Wang, Yan Li, Guohui Ning, Qian Zhang, Xuena Zhang, Wei Zheng, Zhixin Yang
Summary: This study compared the biosorption, transmembrane transport, and biodegradation of Pyr and BaP by Bacillus sp. strain M1. The results showed that BaP had a higher biosorption efficiency and reached peak adsorption efficiency faster than Pyr. Both Pyr and BaP entered the cells by passive transport. In terms of biodegradation, BaP had a significantly higher efficiency than Pyr around days 5-7 of culture. Key enzymes involved in BaP and Pyr degradation were identified.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Fisheries
Fengjun Lei, Yimeng Tian, Jingjing Miao, Luqing Pan, Ruixue Tong, Yueyao Zhou
Summary: This study investigated the effects of Benzo[a]pyrene (B[a]P) on the immune function of Chlamys farreri hemocytes and found that B[a]P caused changes in both detoxification metabolism and immune signal transduction. Additionally, the metabolite of B[a]P, BPDE, mediated signal transduction through the protein tyrosine kinase pathway in bivalves. The study also demonstrated the significant role of the complement and lectin systems in regulating immune response.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Bozena Bukowska, Katarzyna Mokra, Jaromir Michalowicz
Summary: Benzo[a]pyrene (B[a]P) is a representative polycyclic aromatic hydrocarbon (PAH) that is commonly found in the environment and human surroundings. It has been shown to have toxic effects on DNA, reproduction, neurology, and development. The metabolism of B[a]P is mediated by cytochrome P450 (CYP P450) and its polymorphism determines the sensitivity to B[a]P. Additionally, B[a]P may facilitate the replication of viruses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Tingyi Zhao, Huide Miao, Zhanfei Song, Yangyang Li, Na Xia, Zhiyan Zhang, Hongmei Zhang
Summary: In this study, the intervention effect of metformin (MET) on cognitive dysfunction induced by B[a]P in mice was evaluated. The results showed that B[a]P caused cognitive impairment, neuronal damage, and glucolipid metabolism disorder, which were alleviated by MET intervention. MET regulated glucolipid metabolism via inhibiting the FTO/FoxO6 pathway, providing a scientific basis for the neurotoxicity and prevention strategies of B[a]P.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Physical
Yue Liu, Xinguo Ren, Lixin He
Summary: This study identified six possible DNA adducts with BPQ, including four covalently bound adducts and two adducts purely bound by van der Waals interactions. Surprisingly, the two van der Waals-bound adducts have comparable, if not larger, binding energies than the covalent adducts. These findings provide insights into the interactions between PAH metabolites and DNA.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Shaoying Gong, Jiachen Zheng, Junjie Zhang, Jianchun Han
Summary: This study investigated the effect of benzo[a]pyrene (B[a]P) on the function of intestinal epithelial barrier (IEB) and the protective effect of arabinogalactan (AG) against B[a]P-induced IEB dysfunction using a Caco-2 cell monolayer model. B[a]P was found to damage the IEB integrity by inducing cell cytotoxicity, oxidative stress, pro-inflammatory cytokine secretion, down-regulation of tight junction proteins, and activation of the AhR/MAPK signaling pathway. However, AG mitigated B[a]P-induced IEB dysfunction by inhibiting oxidative stress and pro-inflammatory factor secretion.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Environmental
Meiling Yi, Lilan Zhang, Yang Li, Yao Qian
Summary: This study investigates the structural, metabolic, and functional responses of soil microbial communities to benzo[a]pyrene (BaP) contamination. The results suggest that BaP-tolerant microbes establish cooperative relationships and compete with sensitive microbes, leading to enhanced carbon source utilization and restricted nitrogen cycling.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Immunology
Johirul Islam, Alpa Shree, Abul Vafa, Shekh M. Afzal, Sarwat Sultana
Summary: The study highlights the protective effect of Taxifolin on Benzo[a]pyrene-induced lung injury in mice, showing that Taxifolin suppresses oxidative stress and inflammation through stimulating the Nrf2 signaling pathway.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Environmental Sciences
Lynda Saber Cherif, Lei Cao-Lei, Sophie Farinelle, Claude P. Muller, Jonathan D. Turner, Henri Schroeder, Nathalie Grova
Summary: Research suggests that B[a]P may accelerate the onset of brain tumors and neurobehavioral disturbances, with direct neurotoxic effects on the central and peripheral nervous systems, and potentially indirect effects through other organs. The brain has the ability to metabolize B[a]P, leading to significant overexpression of genes in certain brain regions at higher doses. Mice showed reduced anxiety and dose-dependent changes in Nmda subunit expression in cognition-related areas at higher doses, with potential metabolites in serum serving as biomarkers for B[a]P-induced cognitive impairments in the future.
Article
Environmental Sciences
Guozhu Ye, Wenjia Lu, Luyun Zhang, Han Gao, Xu Liao, Xu Zhang, Han Zhang, Jinsheng Chen, Qiansheng Huang
Summary: Polycyclic aromatic hydrocarbon (PAH) exposure is a major risk factor for cardiovascular diseases, and macrophage lipid accumulation is a characteristic event in the pathophysiology of these diseases. Metabolic reprogramming offers potential intervention targets for diseases and toxic effects of environmental pollutants. This study used metabolomics and transcriptomics to uncover metabolic reprogramming in BAPEXPOSED macrophages and identify potential intervention targets. The findings suggest that lipid transport, as well as changes in the metabolism of amino acids, nucleotides, monosaccharides, and organic acids, may play a role in the macrophage lipid accumulation induced by PAH exposure. The study also observed oxidative stress and the activation of antioxidant systems in PAH-exposed macrophages and identified epigallocatechin-3-gallate as a potential inhibitor of reactive oxygen species and lipid accumulation.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Qianyong Shen, Ranran Liu, Jingyi Chen, Guiying Li, Shengtao Ma, Yingxin Yu, Taicheng An
Summary: Occupational workers and residents near petrochemical industry facilities are exposed to multiple contaminants on a daily basis. However, little is known about the co-exposure effects of different pollutants based on biotransformation. This study investigated the changes in toxicity and co-exposure mechanism associated with different monoaromatic hydrocarbons (MAHs) when co-exposed with benzene, toluene, chlorobenzene, or nitrobenzene. The results showed that co-exposure to MAHs negatively affected the detoxification process of benzo[a]pyrene (BaP) and disturbed its metabolic pathways.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Dongyu Li, Jingjing Miao, Luqing Pan, Yueyao Zhou, Zhongyuan Gao, Yaqi Bi, Jian Tang
Summary: This study systematically investigated the lipid metabolism disturbance in scallop digestive glands exposed to Benzo[a]pyrene (B[a]P) through lipidomics, transcriptomics, molecular, and biochemical analysis. Results showed that lipid content increased and membrane structures were disrupted in digestive glands of scallops exposed to 10 μg/L B[a]P. It was speculated that B[a]P induced lipid accumulation by up-regulating lipid synthesis-related gene expression, down-regulating lipolysis-related gene expression, and interfering with lipid transport. This study provides important insights into the mechanisms of lipid metabolism disturbance and bioaccumulation of B[a]P in aquatic organisms.
Article
Biochemistry & Molecular Biology
Wei Lou, Meng-di Zhang, Qi Chen, Tu-Ya Bai, Yu-Xia Hu, Feng Gao, Jun Li, Xiao-Li Lv, Qian Zhang, Fu-Hou Chang
Summary: This study aimed to investigate whether Benzo[a]pyrene (BaP) regulates lipid metabolism via the aryl hydrocarbon receptor (AhR). The results showed that BaP inhibited fat synthesis and oxidation while inducing inflammation by activating AhR, leading to dysfunction of white adipose tissue and metabolic complications.
LIPIDS IN HEALTH AND DISEASE
(2022)
Article
Engineering, Environmental
Hua Meng, Guyanan Li, Wei Wei, Yansen Bai, Yue Feng, Ming Fu, Xin Guan, Mengying Li, Hang Li, Chenming Wang, Jiali Jie, Xiulong Wu, Meian He, Xiaomin Zhang, Sheng Wei, Yangkai Li, Huan Guo
Summary: This study identified 15 CpG sites associated with BPDE-Alb adducts, with methylation levels at 5 sites mediating the association between BPDE-Alb adducts and lung cancer risk. The addition of these CpG sites improved the discrimination for lung cancer compared to traditional factors. These results highlight DNA methylation alterations as potential mediators in lung tumorigenesis induced by B[a]P exposure.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Meng Yang, Jinshao Ye, Huaming Qin, Yan Long, Yi Li
ENVIRONMENTAL POLLUTION
(2017)
Article
Environmental Sciences
Meng Yang, Huaming Qin, Wenhui Wang, Hongling Zhang, Yan Long, Jinshao Ye
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Environmental Sciences
Yi Li, Chongshu Li, Huaming Qin, Meng Yang, Jinshao Ye, Yan Long, Huase Ou
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Environmental Sciences
Chongshu Li, Qiying Lu, Jinshao Ye, Huaming Qin, Yan Long, Lili Wang, Huase Ou
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Engineering, Environmental
Yujia Chen, Jinshao Ye, Ya Chen, Han Hu, Hongling Zhang, Huase Ou
CHEMICAL ENGINEERING JOURNAL
(2019)
Article
Engineering, Environmental
Xiaolong Yu, Hua Yin, Jin Shao Ye, Hui Peng, Guining Lu, Zhi Dang
CHEMICAL ENGINEERING JOURNAL
(2019)
Article
Engineering, Environmental
Wenxin Wang, Henan Yu, Huaming Qin, Yan Long, Jinshao Ye, Yanfen Qu
JOURNAL OF HAZARDOUS MATERIALS
(2020)
Article
Environmental Sciences
Kunliang Yang, Qiao Zhong, Huaming Qin, Yan Long, Huase Ou, Jinshao Ye, Yanfen Qu
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Engineering, Environmental
Wenxiao Zheng, Liuyi Zhu, Sheng Liang, Jinshao Ye, Xin Yang, Zhenchao Lei, Zhang Yan, Yongdong Li, Chaohai Wei, Chunhua Feng
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2020)
Article
Environmental Sciences
Qinglin Zhang, Guiting Fang, Weijian Chen, Xing Zhong, Yan Long, Huaming Qin, Jinshao Ye
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Environmental Sciences
Huiying Guo, Xiaolong Yu, Ziyi Liu, Jieruo Li, Jinshao Ye, Zhengang Zha
ENVIRONMENT INTERNATIONAL
(2020)
Article
Engineering, Environmental
Jiong Gao, Jie Song, Jinshao Ye, Xiaodi Duan, Dionysios D. Dionysiou, Jagjit S. Yadav, Mallikarjuna N. Nadagouda, Lixia Yang, Shenglian Luo
Summary: This study evaluated and compared the toxicity of BPA solutions treated with UV/H2O2 and UV/SPC, revealing the formation of various transformation products (TPs) with different technologies, with unique quinonation TPs detected in UV/H2O2 treated solution at a specific UV dose. The results suggest that while the treatments may increase matrix toxicity, they also decrease bioaccumulation potential of TPs, impacting E. coli with inhibited cell growth, arrested cell cycle, and increased cell death.
Article
Environmental Sciences
Chongshu Li, Changzheng Cui, Jie Zhang, Jing Shen, Baoyan He, Yan Long, Jinshao Ye
Summary: Microbial remediation is an eco-friendly and promising approach for the restoration of petroleum hydrocarbon (PHC) contaminated sites. The degradation of different compounds in the soil samples collected from a petrochemical site by indigenous microbiome and exogenous microbes was evaluated. The study revealed the improvement of microbial diversity and community structure during the bioremediation process, as well as the correlation between microbes and the degradation of PHC-based pollutants.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Linlin Wang, Wenying Yi, Jinshao Ye, Huaming Qin, Yan Long, Meng Yang, Qusheng Li
Article
Engineering, Environmental
Shun-Shun Chen, Xu-Xiu Chen, Tian-Yu Yang, Li Chen, Zheng Guo, Xing-Jiu Huang
Summary: A temperature-modulated sensing strategy was proposed to identify and determine BTEX compounds. Highly effective identification of BTEX was achieved using linear discrimination and convolutional neural network analyses. Additionally, quantitative analysis of concentration was accomplished by establishing the relationship between concentration and response.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Myungkyung Noh, Jeong Yeon Sim, Jisung Kim, Jee Hwan Ahn, Hye-Young Min, Jong-Uk Lee, Jong-Sook Park, Ji Yun Jeong, Jae Young Lee, Shin Yup Lee, Hyo-Jong Lee, Choon-Sik Park, Ho-Young Lee
Summary: This study reveals that chronic exposure to PM induces chronic inflammation and development of COPD by dysregulating NAD+ metabolism and subsequent SIRT1 deficiency in pulmonary macrophages. Activation of SIRT1 by resveratrol effectively mitigates PM-induced inflammation and COPD development. Targeting metabolic and epigenetic reprogramming in macrophages induced by PM is a promising strategy for COPD treatment.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Yu Liu, Linlin Qin, Yiming Qin, Tong Yang, Haoran Lu, Yulong Liu, Qiqi Zhang, Wenyan Liang
Summary: Co/NC/PAC electrode was prepared by compounding ZIF-67 with powder-activated carbon for the electrocatalytic treatment of nitrogen-containing heterocyclic compounds. The degradation efficiency of the four compounds reached 90.2-93.7% under optimal conditions, and the degradation order was pyridazine < pyrimidine < pyrazine < pyridine.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Julien Couturier, Pierre Tamba Oulare, Blanche Collin, Claire Lallemand, Isabelle Kieffer, Julien Longerey, Perrine Chaurand, Jerome Rose, Daniel Borschneck, Bernard Angeletti, Steven Criquet, Renaud Podor, Hamed Pourkhorsandi, Guilhem Arrachart, Clement Levard
Summary: This study analyzes the properties of bauxite residue samples and explores the influence of bauxite ore origin, storage conditions, and storage time. The results show that the speciation of yttrium is related to the origin of bauxite ore, while no significant variation was observed with storage conditions or aging of the residues.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Sakthinarenderan Saikumar, Ravi Mani, Mirunalini Ganesan, Inbakandan Dhinakarasamy, Thavamani Palanisami, Dharani Gopal
Summary: Microplastic contamination in marine ecosystems poses a growing concern due to its trophic transfer and negative effects on marine organisms. This study investigates the transfer and impacts of polystyrene microplastics in an estuarine food chain. The results show that microplastics can be transferred through the food chain, although the transfer rates are low. The exposed organisms exhibit stress responses, suggesting the potential risk of microplastics reaching humans through the food chain.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Review
Engineering, Environmental
Yan-Jiao Li, Ying Yuan, Wen-Bing Tan, Bei-Dou Xi, Hui Wang, Kun-Long Hui, Jia-Bao Chen, Yi-Fan Zhang, Lian-Feng Wang, Ren-Fei Li
Summary: This review investigated and analyzed the distribution, composition, and abundance of heavy metals and antibiotic resistance genes (ARGs) in landfill. The results showed that heavy metals have lasting effects on ARGs, and complexes of heavy metals and organic matter are common in landfill. This study provides a new basis to better understand the horizontal gene transfer (HGT) of ARGs in landfill.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Jessy Joseph, Ari Vaisanen, Ajay B. Patil, Manu Lahtinen
Summary: Efficient and environmentally friendly porous hybrid adsorbent beads have been developed for the removal of arsenic from drinking water. The structural tuning of the adsorbents has been shown to have a significant impact on their adsorption performance, with high crystallinity leading to increased adsorption capacity and selectivity towards As5+.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Yangyang Liu, Minhua Xiao, Kaiqin Huang, Juntao Cui, Hongli Liu, Yingxin Yu, Shengtao Ma, Xihong Liu, Meiqing Lin
Summary: This study measured the levels of phthalate metabolites in breast milk collected from mothers in southern China. The results showed that phthalates are still prevalent in the region, and breastfeeding contributes to phthalate intake in infants. However, the levels detected do not pose significant health risks to infants based on dietary exposure. The increasing exposure to certain phthalates calls for further research into their sources and potential risks.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Zhiqiang Wu, Jianxing Sun, Liting Xu, Hongbo Zhou, Haina Cheng, Zhu Chen, Yuguang Wang, Jichao Yang
Summary: Ocean depth affects microbial diversity, composition, and co-occurrence patterns of microplastic microbial communities. Deterministic processes dominate the assembly of mesopelagic plastisphere microbial communities, while stochastic processes shape the assembly of bathypelagic microbial communities. The relationships between microorganisms in the mesopelagic layer are more complex and stable, with Proteobacteria and Actinobacteriota playing important roles.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Tingting Xiao, Renjie Chen, Chen Cai, Shijie Yuan, Xiaohu Dai, Bin Dong, Zuxin Xu
Summary: Based on the efficiency of catalytic ozonation techniques in enhancing sludge dewaterability, this study investigated its effectiveness in simultaneous reduction of antibiotics and antibiotic resistance genes. The results showed that catalytic ozonation conditioning changed the distribution of antibiotics and achieved high degradation rates. It also significantly reduced the abundance of ARGs, inhibited horizontal gene transfer, and decreased the signal transduction of typical ARGs host bacteria.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Yang Deng, Xiaohong Guan
Summary: This article discusses two different development approaches for ferrate(VI) technology in water treatment, arguing that process integration is a promising method that can drive technological innovation and revolution in water treatment, achieving higher treatment efficiency, reduced costs and energy consumption, and a smaller physical footprint.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Zhe Zhang, Lu Zhang, Zhihao Huang, Yuxin Xu, Qingqing Zhao, Hongju Wang, Meiqing Shi, Xiangnan Li, Kai Jiang, Dapeng Wu
Summary: In this study, a floating catalytic foam was designed and prepared to enhance the mass transfer in immobilized photocatalysts for wastewater treatment. The floating catalytic foam could float on the water surface and establish a temperature gradient, effectively promoting the diffusion and adsorption of target molecules during the photocatalytic process.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Muhammad Nafees, Adiba Khan Sehrish, Sarah Owdah Alomrani, Linlin Qiu, Aasim Saeed, Shoaib Ahmad, Shafaqat Ali, Hongyan Guo
Summary: The accumulation of cadmium and antibiotics in edible plants and fertile soil is a worldwide problem. This study investigated the potential of zinc oxide nanoparticles to alleviate the toxicity of both cadmium and antibiotics and promote spinach growth.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Lurui Wan, Kai Wang, Yuan Chen, Zhiyong Xu, Wenbo Zhao
Summary: In this study, a low viscosity and high thermal stability SO2 absorbent with dual interacting sites was successfully synthesized. The absorbent showed the highest absorption enthalpy change and entropy change values among reported SO2 absorbents, and exhibited lower viscosity and comparable thermal stability to ILs.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Zhengwei Zhou, Guojie Ye, Yang Zong, Zhenyu Zhao, Deli Wu
Summary: This study utilized Mo powder and STPP to enhance the performance of the sodium percarbonate system in pollutant degradation. The presence of Mo and STPP resulted in a higher degradation rate of the model pollutant SMX, with low oxidant consumption. The system generated multiple active species through a series of chain reactions at different pH values, exhibiting excellent performance towards electron-rich pollutants. Furthermore, Mo demonstrated excellent stability and reusability.
JOURNAL OF HAZARDOUS MATERIALS
(2024)