Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health

Glutamine on Intestinal Inflammation: A Mechanistic Perspective

(2017) W-K. Ren et al.   European Journal of Inflammation

Homoarginine, arginine, and relatives: analysis, metabolism, transport, physiology, and pathology

(2015) Dimitrios Tsikas et al.   AMINO ACIDS

l-Leucine and NO-mediated cardiovascular function

(2015) Ying Yang et al.   AMINO ACIDS

The many faces of interferon tau

(2015) Fuller W. Bazer et al.   AMINO ACIDS

Symmetric dimethylarginine (SDMA) serum levels in rheumatoid arthritis: correlations with insulin resistance and disease activity scores

(2015) Theodoros Dimitroulas et al.   AMINO ACIDS

Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease

(2015) Arslan Arinc Kayacelebi et al.   AMINO ACIDS

Dietary essentiality of “nutritionally non-essential amino acids” for animals and humans

(2015) Yongqing Hou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

N-acetylcysteine and intestinal health a focus on its mechanism of action

(2015) Yongqing Hou   Frontiers in Bioscience-Landmark

Gut-Busters: IL-17 Ain’t Afraid of No IL-23

(2015) Natasha Whibley et al.   IMMUNITY

Mucosal Healing in Inflammatory Bowel Diseases

(2015) Annaïg Lan et al.   INFLAMMATORY BOWEL DISEASES

Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids

(2015) Donald L. Zignego et al.   JOURNAL OF BIOMECHANICS

The anti-spasticity drug baclofen alleviates collagen-induced arthritis and regulates dendritic cells

(2015) Shichao Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

L-Glutamate Enhances Barrier and Antioxidative Functions in Intestinal Porcine Epithelial Cells

(2015) Ning Jiao et al.   JOURNAL OF NUTRITION

Excitatory amino acid glutamate: role in peripheral nociceptive transduction and inflammation in experimental and clinical osteoarthritis

(2015) Z.-H. Wen et al.   OSTEOARTHRITIS AND CARTILAGE

Berberine attenuates CCN2-induced IL-1β expression and prevents cartilage degradation in a rat model of osteoarthritis

(2015) Shan-Chi Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The protection mechanism of proline from D-galactosamine hepatitis involves the early activation of ROS-eliminating pathway in the liver

(2015) Yoko Obayashi et al.   SpringerPlus

Glutamine and intestinal barrier function

(2014) Bin Wang et al.   AMINO ACIDS

Methionine deficiency reduces autophagy and accelerates death in intestinal epithelial cells infected with enterotoxigenic Escherichia coli

(2014) Yulong Tang et al.   AMINO ACIDS

l-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells

(2014) Yuhua Zhu et al.   AMINO ACIDS

Effects of dietary l-glutamine supplementation on specific and general defense responses in mice immunized with inactivated Pasteurella multocida vaccine

(2014) Shuai Chen et al.   AMINO ACIDS

l-Glutamine enhances enterocyte growth via activation of the mTOR signaling pathway independently of AMPK

(2014) Dan Yi et al.   AMINO ACIDS

Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs

(2014) Weiwei Wang et al.   AMINO ACIDS

Glycine Stimulates Protein Synthesis and Inhibits Oxidative Stress in Pig Small Intestinal Epithelial Cells

(2014) Weiwei Wang et al.   JOURNAL OF NUTRITION

Dietary Arginine Supplementation of Mice Alters the Microbial Population and Activates Intestinal Innate Immunity

(2014) Wenkai Ren et al.   JOURNAL OF NUTRITION

Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis

(2014) Beata Mickiewicz et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Chondroprotective and anti-inflammatory effects of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants model of osteoarthritis

(2014) Venkanna Balaganur et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Serum Amino Acids Profile and the Beneficial Effects of L-Arginine or L-Glutamine Supplementation in Dextran Sulfate Sodium Colitis

(2014) Wenkai Ren et al.   PLoS One

Therapeutic Effects of Glutamic Acid in Piglets Challenged with Deoxynivalenol

(2014) Miaomiao Wu et al.   PLoS One

Dietary Glutamate Supplementation Ameliorates Mycotoxin-Induced Abnormalities in the Intestinal Structure and Expression of Amino Acid Transporters in Young Pigs

(2014) Jielin Duan et al.   PLoS One

An NMR-Based Metabolomic Approach to Investigate the Effects of Supplementation with Glutamic Acid in Piglets Challenged with Deoxynivalenol

(2014) Miaomiao Wu et al.   PLoS One

Amino Acid Nutrition in Animals: Protein Synthesis and Beyond

(2014) Guoyao Wu et al.   Annual Review of Animal Biosciences

Dietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutrition

(2014) Guoyao Wu   Journal of Animal Science and Biotechnology

Functional amino acids in nutrition and health

(2013) Guoyao Wu   AMINO ACIDS

Dietary l-proline supplementation confers immunostimulatory effects on inactivated Pasteurella multocida vaccine immunized mice

(2013) Wenkai Ren et al.   AMINO ACIDS

Impacts of arginine nutrition on embryonic and fetal development in mammals

(2013) Guoyao Wu et al.   AMINO ACIDS

Dietary l-glutamine supplementation increases Pasteurella multocida burden and the expression of its major virulence factors in mice

(2013) Wenkai Ren et al.   AMINO ACIDS

Glycine metabolism in animals and humans: implications for nutrition and health

(2013) Weiwei Wang et al.   AMINO ACIDS

Dietary supplementation with proline confers a positive effect in both porcine circovirus-infected pregnant and non-pregnant mice

(2013) Wenkai Ren et al.   BRITISH JOURNAL OF NUTRITION

Glutamine modifies immune responses of mice infected with porcine circovirus type 2

(2013) Wenkai Ren et al.   BRITISH JOURNAL OF NUTRITION

Obesity and Osteoarthritis: More Than Just Wear and Tear

(2013) R. C. Koonce et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

L-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in plasma and synovial fluid of patients with knee osteoarthritis

(2013) Valerio Pascale et al.   MEDICAL SCIENCE MONITOR

Biochemical and physiological bases for utilization of dietary amino acids by young Pigs

(2013) Reza Rezaei et al.   Journal of Animal Science and Biotechnology

Proline protects liver from d-galactosamine hepatitis by activating the IL-6/STAT3 survival signaling pathway

(2012) Yoko Obayashi et al.   AMINO ACIDS

Dietary supplementation with monosodium glutamate is safe and improves growth performance in postweaning pigs

(2012) Reza Rezaei et al.   AMINO ACIDS

Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: Findings from the multicenter osteoarthritis study and the osteoarthritis initiative

(2012) David T. Felson et al.   ARTHRITIS AND RHEUMATISM

Dietary arginine supplementation enhances immune responses to inactivated Pasteurella multocida vaccination in mice

(2012) Wenkai Ren et al.   BRITISH JOURNAL OF NUTRITION

Dietary arginine supplementation alleviates immune challenge induced by Salmonella enterica serovar Choleraesuis bacterin potentially through the Toll-like receptor 4-myeloid differentiation factor 88 signalling pathway in weaned piglets

(2012) Yu Chen et al.   BRITISH JOURNAL OF NUTRITION

Prognostic biomarkers in osteoarthritis

(2012) Mukundan Attur et al.   CURRENT OPINION IN RHEUMATOLOGY

Synergies between vaccination and dietary arginine and glutamine supplementation improve the immune response of channel catfish against Edwardsiella ictaluri

(2012) Camilo Pohlenz et al.   FISH & SHELLFISH IMMUNOLOGY

Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes

(2012) Mireille Bentz et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

1H NMR Spectroscopy of Serum Reveals Unique Metabolic Fingerprints Associated with Subtypes of Surgically Induced Osteoarthritis in Sheep

(2012) Anthony D. Maher et al.   JOURNAL OF PROTEOME RESEARCH

Correlation of Plasma Amino Acid Concentrations and Chondroprotective Effects of Glucosamine and Fish Collagen Peptide on the Development of Osteoarthritis

(2012) Akihiro OHNISHI et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

L-arginine Supplementation Improves Responses to Injury and Inflammation in Dextran Sulfate Sodium Colitis

(2012) Lori A. Coburn et al.   PLoS One

Phosphorylation of osteopontin in osteoarthritis degenerative cartilage and its effect on matrix metalloprotease 13

(2012) Mai Xu et al.   RHEUMATOLOGY INTERNATIONAL

Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee

(2012) Walter P Maksymowych et al.   ARTHRITIS RESEARCH & THERAPY

Functional Amino Acids in Growth, Reproduction, and Health

(2012) Guoyao Wu   Advances in Nutrition

Nutritional Interventions to Prevent and Treat Osteoarthritis. Part II: Focus on Micronutrients and Supportive Nutraceuticals

(2012) Hector L. Lopez   PM&R

Effect of dietary arginine supplementation on reproductive performance of mice with porcine circovirus type 2 infection

(2011) Wenkai Ren et al.   AMINO ACIDS

Dietary l-glutamine supplementation improves pregnancy outcome in mice infected with type-2 porcine circovirus

(2011) Wenkai Ren et al.   AMINO ACIDS

Future therapeutics for osteoarthritis

(2011) Johanne Martel-Pelletier et al.   BONE

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

Combined microwave irradiation and intraarticular glutamine administration-induced HSP70 expression therapy prevents cartilage degradation in a rat osteoarthritis model

(2011) Shinya Fujita et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Beneficial Effect of Creatine Supplementation in Knee Osteoarthritis

(2011) MANOEL NEVES et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

(2011) Stanley B Cohen et al.   ARTHRITIS RESEARCH & THERAPY

Proline and hydroxyproline metabolism: implications for animal and human nutrition

(2010) Guoyao Wu et al.   AMINO ACIDS

Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis

(2010) G. Zhai et al.   ANNALS OF THE RHEUMATIC DISEASES

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

TRIENNIAL GROWTH SYMPOSIUM: Important roles for L-glutamine in swine nutrition and production1,2

(2010) G. Wu et al.   JOURNAL OF ANIMAL SCIENCE

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

(2010) Jérémie Sellam et al.   Nature Reviews Rheumatology

Immune response of broiler chickens fed different levels of arginine and vitamin E to a coccidiosis vaccine and Eimeria challenge

(2010) C. Perez-Carbajal et al.   POULTRY SCIENCE

A peripheral neuroimmune link: glutamate agonists upregulate NMDA NR1 receptor mRNA and protein, vimentin, TNF-α, and RANTES in cultured human synoviocytes

(2009) Terry A. McNearney et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

l-Glutamine or l-alanyl-l-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytes

(2009) Tony E. Haynes et al.   AMINO ACIDS

High fat feeding and dietary l-arginine supplementation differentially regulate gene expression in rat white adipose tissue

(2009) Wenjuan Jobgen et al.   AMINO ACIDS

Amino acids: metabolism, functions, and nutrition

(2009) Guoyao Wu   AMINO ACIDS

Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study

(2009) X. Chevalier et al.   ARTHRITIS AND RHEUMATISM

Spinally applied ketamine or morphine attenuate peripheral inflammation and hyperalgesia in acute and chronic phases of experimental arthritis

(2009) Michael Karl Boettger et al.   BRAIN BEHAVIOR AND IMMUNITY

Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis

(2009) M. Blagojevic et al.   OSTEOARTHRITIS AND CARTILAGE

Dietary arginine stimulates humoral and cell-mediated immunity in chickens vaccinated and challenged against hydropericardium syndrome virus

(2009) K. Munir et al.   POULTRY SCIENCE

Arginine metabolism and nutrition in growth, health and disease

(2008) Guoyao Wu et al.   AMINO ACIDS

Dietary l-Arginine Supplementation Reduces White Fat Gain and Enhances Skeletal Muscle and Brown Fat Masses in Diet-Induced Obese Rats

(2008) Wenjuan Jobgen et al.   JOURNAL OF NUTRITION