Knockdown of FOXO3a induces epithelial-mesenchymal transition and promotes metastasis of pancreatic ductal adenocarcinoma by activation of the β-catenin/TCF4 pathway through SPRY2

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MiR-592 Promotes Gastric Cancer Proliferation, Migration, and Invasion Through the PI3K/AKT and MAPK/ERK Signaling Pathways by Targeting Spry2

(2018) Yu He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Lentiviral CRISPR/Cas9 vector mediated miR-21 gene editing inhibits the epithelial to mesenchymal transition in ovarian cancer cells

(2017) Wenying Huo et al.   Journal of Cancer

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells

(2016) LiJun Yang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis

(2016) Sebastian R. Nielsen et al.   NATURE CELL BIOLOGY

FOXO3a modulates WNT/β-catenin signaling and suppresses epithelial-to-mesenchymal transition in prostate cancer cells

(2015) Hao Liu et al.   CELLULAR SIGNALLING

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150

(2015) A Barbáchano et al.   ONCOGENE

Pancreatic Adenocarcinoma

(2015) David P. Ryan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma

(2014) D. Ni et al.   CLINICAL CANCER RESEARCH

microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition

(2014) Aditya Parikh et al.   Nature Communications

FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

(2013) E. E. Santo et al.   CANCER RESEARCH

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis

(2012) Keun Hur et al.   GUT

EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin

(2012) Sharmila Shankar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Identification of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses

(2011) K. Karube et al.   BLOOD

Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells

(2011) G Fu et al.   ONCOGENE

Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas

(2011) H-J Kwak et al.   ONCOGENE

miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2

(2010) Yihui Ma et al.   CANCER LETTERS

Foxo3a Suppression of Urothelial Cancer Invasiveness through Twist1, Y-Box-Binding Protein 1, and E-Cadherin Regulation

(2010) M. Shiota et al.   CLINICAL CANCER RESEARCH

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells

(2009) Chie Kudo-Saito et al.   CANCER CELL

Biomarkers for epithelial-mesenchymal transitions

(2009) Michael Zeisberg et al.   JOURNAL OF CLINICAL INVESTIGATION

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY