Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys With Duchenne Muscular Dystrophy

Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study

(2018) Craig M McDonald et al.   LANCET

Phase 1 trial of vamorolone, a first-in-class steroid, shows improvements in side effects via biomarkers bridged to clinical outcomes

(2018) Eric P. Hoffman et al.   STEROIDS

Modeling the influence of chronopharmacological administration of synthetic glucocorticoids on the hypothalamic-pituitary-adrenal axis

(2018) Rohit T. Rao et al.   CHRONOBIOLOGY INTERNATIONAL

Membrane Stabilization by Modified Steroid Offers a Potential Therapy for Muscular Dystrophy Due to Dysferlin Deficit

(2018) Sen Chandra Sreetama et al.   MOLECULAR THERAPY

Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug

(2018) Laurie S. Conklin et al.   PHARMACOLOGICAL RESEARCH

VBP15, a novel dissociative steroid compound, reduces NFκB-induced expression of inflammatory cytokines in vitro and symptoms of murine trinitrobenzene sulfonic acid-induced colitis

(2016) Jesse M. Damsker et al.   INFLAMMATION RESEARCH

A novel dissociative steroid VBP15 reduces MUC5AC gene expression in airway epithelial cells but lacks the GRE mediated transcriptional properties of dexamethasone

(2016) Lindsay M. Garvin et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Vamorolone, a dissociative steroidal compound, reduces pro-inflammatory cytokine expression in glioma cells and increases activity and survival in a murine model of cortical tumor

(2016) Elizabeth Wells et al.   Oncotarget

Gastrointestinal Dysfunction in Patients with Duchenne Muscular Dystrophy

(2016) Christian M. Lo Cascio et al.   PLoS One

Prednisone/prednisolone and deflazacort regimens in the CINRG Duchenne Natural History Study

(2015) Luca Bello et al.   NEUROLOGY

VBP15, a Novel Anti-Inflammatory, is Effective at Reducing the Severity of Murine Experimental Autoimmune Encephalomyelitis

(2014) Blythe C. Dillingham et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy

(2014) Sherry Dadgar et al.   JOURNAL OF CELL BIOLOGY

Inhaled corticosteroids in children: effects on bone mineral density and growth

(2014) Anne L Fuhlbrigge et al.   Lancet Respiratory Medicine

VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid

(2013) Erica K.M. Reeves et al.   BIOORGANIC & MEDICINAL CHEMISTRY

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

(2013) Christopher R. Heier et al.   EMBO Molecular Medicine

Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches

(2013) Rebecca J. Fairclough et al.   NATURE REVIEWS GENETICS

VBP15, a Glucocorticoid Analogue, Is Effective at Reducing Allergic Lung Inflammation in Mice

(2013) Jesse M. Damsker et al.   PLoS One

Randomized, blinded trial of weekend vs daily prednisone in Duchenne muscular dystrophy

(2011) D. M. Escolar et al.   NEUROLOGY

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

(2009) Katharine Bushby et al.   LANCET NEUROLOGY