Curcumin prevents high glucose damage in retinal pigment epithelial cells through ERK1/2-mediated activation of the Nrf2/HO-1 pathway

Curcumin protects cortical neurons against oxygen and glucose deprivation/reoxygenation injury through flotillin-1 and extracellular signal-regulated kinase1/2 pathway

(2018) Zhengyu Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potential Interplay between Hyperosmolarity and Inflammation on Retinal Pigmented Epithelium in Pathogenesis of Diabetic Retinopathy

(2018) François Willermain et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Trophic effect of PACAP on human corneal endothelium

(2018) Grazia Maugeri et al.   PEPTIDES

Retinal Protection and Distribution of Curcumin in Vitro and in Vivo

(2018) Chiara B. M. Platania et al.   Frontiers in Pharmacology

Curcumin confers hepatoprotection against AFB1-induced toxicity via activating autophagy and ameliorating inflammation involving Nrf2/HO-1 signaling pathway

(2018) Ishfaq Muhammad et al.   MOLECULAR BIOLOGY REPORTS

Intonation of Nrf2 and Hif1-α pathway by curcumin prophylaxis: A potential strategy to augment survival signaling under hypoxia

(2018) Titto Mathew et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Anti-apoptotic effects ofCurcuma longaL. extract and its curcuminoids against blue light-induced cytotoxicity in A2E-laden human retinal pigment epithelial cells

(2017) Sang-il Park et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells

(2017) Valeria Pittalà et al.   Oxidative Medicine and Cellular Longevity

Reversal of Beta-Amyloid-Induced Neurotoxicity in PC12 Cells by Curcumin, the Important Role of ROS-Mediated Signaling and ERK Pathway

(2016) Cun-dong Fan et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Curcumin Attenuates Retinal Vascular Leakage by Inhibiting Calcium/Calmodulin-Dependent Protein Kinase II Activity in Streptozotocin-Induced Diabetes

(2016) Jun Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nap Interferes with Hypoxia-Inducible Factors and VEGF Expression in Retina of Diabetic Rats

(2016) Agata Grazia D’Amico et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

VEGF-B inhibits hyperglycemia- and Macugen-induced retinal apoptosis

(2016) Delong Huang et al.   Scientific Reports

Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis

(2015) Dong-Il Kim et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Permanent Culture of Macrophages at Physiological Oxygen Attenuates the Antioxidant and Immunomodulatory Properties of Dimethyl Fumarate

(2015) Benjamin Haas et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions

(2015) Roberta Foresti et al.   PHARMACOLOGICAL RESEARCH

Design and Synthesis of New Hybrid Molecules That Activate the Transcription Factor Nrf2 and Simultaneously Release Carbon Monoxide

(2014) Jayne Louise Wilson et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nrf2 signaling modulates cigarette smoke-induced complement activation in retinal pigmented epithelial cells

(2014) Lei Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heme Oxygenase-1 As a Target for Drug Discovery

(2013) Roberto Motterlini et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of phospholipases A2 in diabetic retinopathy: In vitro and in vivo studies

(2013) Gabriella Lupo et al.   BIOCHEMICAL PHARMACOLOGY

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

(2013) Roberta Foresti et al.   PHARMACOLOGICAL RESEARCH

Fortified Extract of Red Berry,Ginkgo biloba, and White Willow Bark in Experimental Early Diabetic Retinopathy

(2013) Claudio Bucolo et al.   Journal of Diabetes Research

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats

(2012) Claudio Bucolo et al.   BIOCHEMICAL PHARMACOLOGY

An association between polymorphism of the heme oxygenase-1 and -2 genes and age-related macular degeneration

(2011) Ewelina Synowiec et al.   MOLECULAR BIOLOGY REPORTS

Age-Related Retinopathy in NRF2-Deficient Mice

(2011) Zhenyang Zhao et al.   PLoS One

Epidermal growth factor receptor (EGFR) and neuregulin (Neu) activation in human airway epithelial cells exposed to nickel acetate

(2011) S. Giunta et al.   TOXICOLOGY IN VITRO

The Retinal Pigment Epithelium in Health and Disease

(2010) J. R. Sparrrow et al.   CURRENT MOLECULAR MEDICINE

The Retinal Pigment Epithelium: Something More than a Constituent of the Blood-Retinal Barrier—Implications for the Pathogenesis of Diabetic Retinopathy

(2010) Rafael Simó et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Electrophilic tuning of the chemoprotective natural product sulforaphane

(2010) Y.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focus on molecules: Heme oxygenase-1

(2009) Claudio Bucolo et al.   EXPERIMENTAL EYE RESEARCH

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

(2008) Patrick L. Apopa et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting

(2008) W Todd Cade   PHYSICAL THERAPY