Iron overload threatens the growth of osteoblast cells via inhibiting the PI3K/AKT/FOXO3a/DUSP14 signaling pathway

DUSP14 knockout accelerates cardiac ischemia reperfusion (IR) injury through activating NF-κB and MAPKs signaling pathways modulated by ROS generation

(2018) Bin Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oocyte-G1 promotes male germ cell apoptosis through activation of Caspase-3

(2018) Lin Hou et al.   GENE

Hepatocyte DUSP14 maintains metabolic homeostasis and suppresses inflammation in the liver

(2018) Siyuan Wang et al.   HEPATOLOGY

Critical role of FOXO3a in carcinogenesis

(2018) Ying Liu et al.   Molecular Cancer

Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis

(2017) Xiao Chen et al.   FASEB JOURNAL

Overexpression of FoxO3a is associated with glioblastoma progression and predicts poor patient prognosis

(2017) Zhongrun Qian et al.   INTERNATIONAL JOURNAL OF CANCER

Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity

(2017) Lich Thi Nguyen et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway

(2017) Qi Xiao et al.   Molecular Medicine Reports

Current Review of Iron Overload and Related Complications in Hematopoietic Stem Cell Transplantation

(2017) Erden Atilla et al.   Turkish Journal of Hematology

Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis

(2017) Xiao Chen et al.   Cell Death & Disease

Clinical Impact and Cellular Mechanisms of Iron Overload-Associated Bone Loss

(2017) Viktória Jeney   Frontiers in Pharmacology

TRIM14 regulates cell proliferation and invasion in osteosarcoma via promotion of the AKT signaling pathway

(2017) Guoxing Xu et al.   Scientific Reports

Dual-specificity phosphatase 14 protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction through inactivation of TAK1-P38MAPK/-JNK1/2 signaling pathway

(2016) Chang-Yi Li et al.   BASIC RESEARCH IN CARDIOLOGY

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Iron overload induced death of osteoblasts in vitro: involvement of the mitochondrial apoptotic pathway

(2016) Qing Tian et al.   PeerJ

FOXO3a and Posttranslational Modifications Mediate Glucocorticoid Sensitivity in B-ALL

(2015) F. Consolaro et al.   MOLECULAR CANCER RESEARCH

ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice

(2015) Xiao Chai et al.   Scientific Reports

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Expression of Dual-Specificity Phosphatase 5 Pseudogene 1 (DUSP5P1) in Tumor Cells

(2014) Martin S. Staege et al.   PLoS One

IGF1 Receptor Signaling Regulates Adaptive Radioprotection in Glioma Stem Cells

(2013) Satoru Osuka et al.   STEM CELLS

Iron overload accelerates bone loss in healthy postmenopausal women and middle-aged men: A 3-year retrospective longitudinal study

(2012) Beom-Jun Kim et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Iron homeostasis in osteoporosis and its clinical implications

(2012) G. F. Li et al.   OSTEOPOROSIS INTERNATIONAL

Matrine Induces Apoptosis in Human Acute Myeloid Leukemia Cells via the Mitochondrial Pathway and Akt Inactivation

(2012) Shenghui Zhang et al.   PLoS One

Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype

(2011) Victor Chun Lam Wong et al.   INTERNATIONAL JOURNAL OF CANCER

Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway

(2011) Xiaoman Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Overproduction, purification and structure determination of human dual-specificity phosphatase 14

(2009) George T. Lountos et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Excess iron inhibits osteoblast metabolism

(2009) Kanako Yamasaki et al.   TOXICOLOGY LETTERS

PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells

(2008) Dan Li et al.   ANTI-CANCER DRUGS