Cyclooxygenase-2 is Essential for Mediating the Effects of Calcium Ions on Stimulating Phosphorylation of Tau at the Sites of Ser 396 and Ser 404

Prostaglandin I2upregulates the expression of anterior pharynx-defective-1α and anterior pharynx-defective-1β in amyloid precursor protein/presenilin 1 transgenic mice

(2016) Pu Wang et al.   AGING CELL

Renoprotective effect of berberineviaregulating the PGE2-EP1-Gαq-Ca2+signalling pathway in glomerular mesangial cells of diabetic rats

(2016) Wei-Jian Ni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

By suppressing the expression of anterior pharynx-defective-1α and -1β and inhibiting the aggregation of β-amyloid protein, magnesium ions inhibit the cognitive decline of amyloid precursor protein/presenilin 1 transgenic mice

(2015) Xin Yu et al.   FASEB JOURNAL

Motor and cognitive deficits in aged tau knockout mice in two background strains

(2014) Peng Lei et al.   Molecular Neurodegeneration

PKB/SGK-dependent GSK3-phosphorylation in the regulation of LPS-induced Ca2+ increase in mouse dendritic cells

(2013) Antonella Russo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ca2+Influx through Store-operated Ca2+Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

(2013) William Zeiger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulation of COX-2/PGE2 by ET-1 Mediated Through Ca2+-Dependent Signals in Mouse Brain Microvascular Endothelial Cells

(2013) Chih-Chung Lin et al.   MOLECULAR NEUROBIOLOGY

Signaling via the prostaglandin E2 receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia

(2011) Xibin Liang et al.   JOURNAL OF CLINICAL INVESTIGATION

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

(2011) Kelley Bromley-Brits et al.   Jove-Journal of Visualized Experiments

Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-κB activation

(2010) Pu Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice

(2010) Daniel W. Wesson et al.   BEHAVIOURAL BRAIN RESEARCH

Role of prostanoid IP and EP receptors in mediating vasorelaxant responses to PGI2 analogues in rat tail artery: Evidence for Gi/o modulation via EP3 receptors

(2010) Nelson N. Orie et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

(2010) Angelo Demuro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uptake, Release, and Metabolism of Citrate in Neurons and Astrocytes in Primary Cultures

(2010) Niels Westergaard et al.   JOURNAL OF NEUROCHEMISTRY

A Mouse Model of Amyloid   Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo

(2010) T. Tomiyama et al.   JOURNAL OF NEUROSCIENCE

Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model

(2010) Xu Wang et al.   Molecular Neurodegeneration

Roles of the prostaglandin E2 receptors EP subtypes in Alzheimer’s disease

(2010) Li-Li Wei et al.   Neuroscience Bulletin

Proteasome-caspase-cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells

(2009) Lisette T. Arnaud et al.   JOURNAL OF NEUROCHEMISTRY

Nav1.7 sodium channel-induced Ca2+ influx decreases tau phosphorylation via glycogen synthase kinase-3β in adrenal chromaffin cells

(2009) Tasuku Kanai et al.   NEUROCHEMISTRY INTERNATIONAL

Ibuprofen reduces Aβ, hyperphosphorylated tau and memory deficits in Alzheimer mice

(2008) Ann C. McKee et al.   BRAIN RESEARCH

Coexistences of insulin signaling-related proteins and choline acetyltransferase in neurons

(2008) Hongjuan Wang et al.   BRAIN RESEARCH

Therapeutic Targets in Prostaglandin E2 Signaling for Neurologic Disease

(2008) P. Cimino et al.   CURRENT MEDICINAL CHEMISTRY

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

(2008) King-Ho Cheung et al.   NEURON

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES