2018 APLAR axial spondyloarthritis treatment recommendations

The global burden of tuberculosis: results from the Global Burden of Disease Study 2015

(2018) Hmwe H Kyu et al.   LANCET INFECTIOUS DISEASES

Risankizumab, an IL-23 inhibitor, for ankylosing spondylitis: results of a randomised, double-blind, placebo-controlled, proof-of-concept, dose-finding phase 2 study

(2018) Dominique Baeten et al.   ANNALS OF THE RHEUMATIC DISEASES

Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis

(2018) Atul Deodhar et al.   Arthritis & Rheumatology

Nonsteroidal anti-inflammatory drugs in chronic pain: implications of new data for clinical practice

(2018) Kok Yuen Ho et al.   Journal of Pain Research

Hepatitis B Reactivation Associated With Immune Suppressive and Biological Modifier Therapies: Current Concepts, Management Strategies, and Future Directions

(2017) Rohit Loomba et al.   GASTROENTEROLOGY

A practical approach to vaccination of patients with autoimmune inflammatory rheumatic diseases in Australia

(2017) Peter K. K. Wong et al.   INTERNAL MEDICINE JOURNAL

Efficacy and safety of secukinumab in Asian patients with active ankylosing spondylitis: 52-week pooled results from two phase 3 studies

(2017) James C.-C. Wei et al.   International Journal of Rheumatic Diseases

Secukinumab efficacy in anti-TNF-naive and anti-TNF-experienced subjects with active ankylosing spondylitis: results from the MEASURE 2 Study

(2016) Joachim Sieper et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of ustekinumab in psoriatic arthritis patients with peripheral arthritis and physician-reported spondylitis: post-hoc analyses from two phase III, multicentre, double-blind, placebo-controlled studies (PSUMMIT-1/PSUMMIT-2)

(2016) Arthur Kavanaugh et al.   ANNALS OF THE RHEUMATIC DISEASES

Cancer risk in patients with spondyloarthritis treated with TNF inhibitors: a collaborative study from the ARTIS and DANBIO registers

(2016) Karin Hellgren et al.   ANNALS OF THE RHEUMATIC DISEASES

Pregnancy Outcomes in the Tofacitinib Safety Databases for Rheumatoid Arthritis and Psoriasis

(2016) Megan E. B. Clowse et al.   DRUG SAFETY

Risk of infections using anti-TNF agents in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: a systematic review and meta-analysis

(2016) Silvia Minozzi et al.   Expert Opinion On Drug Safety

Efficacy and safety of etanercept in patients from Latin America, Central Europe and Asia with early non-radiographic axial spondyloarthritis

(2016) James Cheng-Chung Wei et al.   International Journal of Rheumatic Diseases

Systematic review of the efficacy and safety of biological therapy for inflammatory conditions in HIV-infected individuals

(2016) DL Fink et al.   INTERNATIONAL JOURNAL OF STD & AIDS

The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013

(2016) Jeffrey D Stanaway et al.   LANCET

Comparative Effectiveness of Biologic Therapy Regimens for Ankylosing Spondylitis

(2016) Chao Chen et al.   MEDICINE

Assessment of clinical efficacy and safety in a randomized double-blind study of etanercept and sulfasalazine in patients with ankylosing spondylitis from Eastern/Central Europe, Latin America, and Asia

(2016) Nemanja Damjanov et al.   RHEUMATOLOGY INTERNATIONAL

The Effectiveness of Exergames in Patients with Ankylosing Spondylitis: A Randomized Controlled Trial

(2016) ALİ KARAHAN et al.   Advances in Clinical and Experimental Medicine

Low-dose modified-release prednisone in axial spondyloarthritis: 3-month efficacy and tolerability

(2016) Francesca Bandinelli et al.   Drug Design Development and Therapy

Treatment patterns, complications, and direct medical costs associated with ankylosing spondylitis in Chinese urban patients: a retrospective claims dataset analysis

(2016) Jinghu Li et al.   JOURNAL OF MEDICAL ECONOMICS

Effect of continuous versus on-demand treatment of ankylosing spondylitis with diclofenac over 2 years on radiographic progression of the spine: results from a randomised multicentre trial (ENRADAS)

(2015) Joachim Sieper et al.   ANNALS OF THE RHEUMATIC DISEASES

THU0207 Comparative Analysis of the Effectiveness of anti-TNF Therapies in Non-Radiographic Axial Spondyloarthritis Using Novel Statistical Techniques: Table 1.

(2015) A. Benedict et al.   ANNALS OF THE RHEUMATIC DISEASES

Impaired response to treatment with tumour necrosis factor α inhibitors in smokers with axial spondyloarthritis

(2015) Adrian Ciurea et al.   ANNALS OF THE RHEUMATIC DISEASES

The effect of comedication with conventional synthetic disease modifying antirheumatic drugs on TNF inhibitor drug survival in patients with ankylosing spondylitis and undifferentiated spondyloarthritis: results from a nationwide prospective study

(2015) Elisabeth Lie et al.   ANNALS OF THE RHEUMATIC DISEASES

Development of an ASAS-endorsed recommendation for the early referral of patients with a suspicion of axial spondyloarthritis

(2015) Denis Poddubnyy et al.   ANNALS OF THE RHEUMATIC DISEASES

Treatment considerations in patients with concomitant viral infection and autoimmune rheumatic diseases

(2015) Worawit Louthrenoo   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis – an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks

(2015) Carmelo Scarpignato et al.   BMC Medicine

Pregnancy outcome after TNF-α inhibitor therapy during the first trimester: a prospective multicentre cohort study

(2015) Corinna Weber-Schoendorfer et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Successful treatment with ustekinumab of psoriasis vulgaris in a patient undergoing hemodialysis

(2015) Kulsupa Nimmannitya et al.   JOURNAL OF DERMATOLOGY

Ustekinumab treatment in patients with psoriasis undergoing hemodialysis

(2015) Yoshinori Umezawa et al.   JOURNAL OF DERMATOLOGY

Is Etanercept 25 mg Once Weekly as Effective as 50 mg at Maintaining Response in Patients with Ankylosing Spondylitis? A Randomized Control Trial

(2015) M. Yates et al.   JOURNAL OF RHEUMATOLOGY

2014 Update of the Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Treatment Recommendations for the Management of Spondyloarthritis. Part I: Principles of the Management of Spondyloarthritis in Canada

(2015) S. Rohekar et al.   JOURNAL OF RHEUMATOLOGY

Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis

(2015) Dominique Baeten et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of tobacco smoking on response to tumour necrosis factor-alpha inhibitor treatment in patients with ankylosing spondylitis: results from the Danish nationwide DANBIO registry

(2015) Bente Glintborg et al.   RHEUMATOLOGY

Effect of Certolizumab Pegol Over Ninety-Six Weeks in Patients With Axial Spondyloarthritis: Results from a Phase III Randomized Trial

(2015) J. Sieper et al.   Arthritis & Rheumatology

American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

(2015) Michael M. Ward et al.   Arthritis & Rheumatology

Referral Patterns, Diagnosis, and Disease Management of Patients With Axial Spondyloarthritis

(2015) Désirée van der Heijde et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

FRI0411 Response and drug survival of sulfasalazine in an observational study (nor-dmard) of dmard-naïve patients with axial spondyloarthritis (SPA)

(2014) K. M. Fagerli et al.   ANNALS OF THE RHEUMATIC DISEASES

THU0204 The Positive Effect of Stringent Criteria for Purified Protein Derivation (PPD) Skin Test on Patients Treated with Certolizumab Pegol

(2014) J. Vencovsky et al.   ANNALS OF THE RHEUMATIC DISEASES

Golimumab administered subcutaneously every 4 weeks in ankylosing spondylitis: 5-year results of the GO-RAISE study

(2014) Atul Deodhar et al.   ANNALS OF THE RHEUMATIC DISEASES

Prevalence of depressive and anxiety disorders and validation of the Hospital Anxiety and Depression Scale as a screening tool in axial spondyloarthritis patients

(2014) Cynthia Y. Y. Chan et al.   International Journal of Rheumatic Diseases

Adalimumab Significantly Reduces the Recurrence Rate of Anterior Uveitis in Patients with Ankylosing Spondylitis

(2014) J. C. van Denderen et al.   JOURNAL OF RHEUMATOLOGY

Prevalence of reactivation of hepatitis B virus replication in rheumatoid arthritis patients

(2014) Yukitomo Urata et al.   Modern Rheumatology

Vaccination of patients with autoimmune inflammatory rheumatic diseases

(2014) Johanna Westra et al.   Nature Reviews Rheumatology

Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials

(2014) Richard G. Langley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of High Intensity Exercise on Disease Activity and Cardiovascular Risk in Active Axial Spondyloarthritis: A Randomized Controlled Pilot Study

(2014) Silje Halvorsen Sveaas et al.   PLoS One

Is there a role for sulphasalazine in axial spondyloarthritis in the era of TNF inhibition? Data from the NOR-DMARD longitudinal observational study

(2014) K. M. Fagerli et al.   RHEUMATOLOGY

Smoking did not modify the effects of anti-TNF treatment on health-related quality of life among Australian ankylosing spondylitis patients

(2014) A. S. R. Kydd et al.   RHEUMATOLOGY

Safety and efficacy of golimumab in Chinese patients with active ankylosing spondylitis: 1-year results of a multicentre, randomized, double-blind, placebo-controlled phase III trial

(2014) C. Bao et al.   RHEUMATOLOGY

Risk of tuberculosis in patients with chronic immune-mediated inflammatory diseases treated with biologics and tofacitinib: a systematic review and meta-analysis of randomized controlled trials and long-term extension studies

(2014) Alejandro Souto et al.   RHEUMATOLOGY

Effect of anti-tumor necrosis factor alpha treatment of rheumatoid arthritis and chronic kidney disease

(2014) Hyun Woo Kim et al.   RHEUMATOLOGY INTERNATIONAL

Burden of Total and Cause-Specific Mortality Related to Tobacco Smoking among Adults Aged ≥45 Years in Asia: A Pooled Analysis of 21 Cohorts

(2014) Wei Zheng et al.   PLOS MEDICINE

Efficacy of certolizumab pegol on signs and symptoms of axial spondyloarthritis including ankylosing spondylitis: 24-week results of a double-blind randomised placebo-controlled Phase 3 study

(2013) R Landewé et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial

(2013) H Haibel et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of adalimumab in Chinese adults with active ankylosing spondylitis: results of a randomised, controlled trial

(2013) Feng Huang et al.   ANNALS OF THE RHEUMATIC DISEASES

Long-Term Efficacy of Adalimumab After Drug Withdrawal and Retreatment in Patients With Active Non-Radiographically Evident Axial Spondyloarthritis Who Experience a Flare

(2013) H. Haibel et al.   ARTHRITIS AND RHEUMATISM

Spondyloarthritis and smoking: towards a new insight into the disease

(2013) Daniel Wendling et al.   Expert Review of Clinical Immunology

Efficacy and safety of ustekinumab in a patient with chronic renal failure on hemodialysis

(2013) Blanca de Unamuno Bustos et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology

(2013) C. C. Mok et al.   International Journal of Rheumatic Diseases

Pharmacokinetics of tofacitinib, a janus kinase inhibitor, in patients with impaired renal function and end-stage renal disease

(2013) Sriram Krishnaswami et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials

(2013)   LANCET

Global prevalence of ankylosing spondylitis

(2013) L. E. Dean et al.   RHEUMATOLOGY

Tumor necrosis factor-α inhibitors and chronic hepatitis C: A comprehensive literature review

(2013) Maurizio Pompili   WORLD JOURNAL OF GASTROENTEROLOGY

Long-term outcome of patients with active ankylosing spondylitis with etanercept-sustained efficacy and safety after seven years

(2013) Xenofon Baraliakos et al.   ARTHRITIS RESEARCH & THERAPY

Ankylosing Spondylitis: Chinese Perspective, Clinical Phenotypes, and Associated Extra-articular Systemic Features

(2013) Huei-Huang Ho et al.   Current Rheumatology Reports

Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1)

(2012) Joachim Sieper et al.   ANNALS OF THE RHEUMATIC DISEASES

Frequency and duration of drug-free remission after 1 year of treatment with etanercept versus sulfasalazine in early axial spondyloarthritis: 2 year data of the ESTHER trial

(2012) In-Ho Song et al.   ANNALS OF THE RHEUMATIC DISEASES

Tumor necrosis factor α inhibitor therapy and cancer risk in chronic immune-mediated diseases

(2012) Kevin Haynes et al.   ARTHRITIS AND RHEUMATISM

Placental Transfer of Anti–Tumor Necrosis Factor Agents in Pregnant Patients With Inflammatory Bowel Disease

(2012) Uma Mahadevan et al.   Clinical Gastroenterology and Hepatology

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

Infliximab and Adalimumab Use During Breastfeeding

(2012) Juliane Fritzsche et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Prevalence of axial spondylarthritis in the United States: Estimates from a cross-sectional survey

(2012) John D. Reveille et al.   ARTHRITIS CARE & RESEARCH

Comprehensive tuberculosis screening program in patients with inflammatory arthritides treated with golimumab, a human anti-tumor necrosis factor antibody, in Phase III clinical trials

(2012) Elizabeth C. Hsia et al.   ARTHRITIS CARE & RESEARCH

Adalimumab treatment in patients with rheumatoid arthritis with renal insufficiency

(2012) Keiichi Sumida et al.   ARTHRITIS CARE & RESEARCH

Indirect comparison of the effects of anti-TNF biological agents in patients with Ankylosing Spondylitis by means of a Mixed Treatment Comparison performed on efficacy data from published randomised, controlled trials

(2012) A. Migliore et al.   JOURNAL OF MEDICAL ECONOMICS

Clinical and economic burden of extra-articular manifestations in ankylosing spondylitis patients treated with anti-tumor necrosis factor agents

(2012) Xin Gao et al.   JOURNAL OF MEDICAL ECONOMICS

High intra-uterine exposure to infliximab following maternal anti-TNF treatment during pregnancy

(2011) Z. Zelinkova et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Efficacy of etanercept on rheumatic signs and pulmonary function tests in advanced ankylosing spondylitis: results of a randomised double-blind placebo-controlled study (SPINE)

(2011) M. Dougados et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register

(2011) S. M. M. Verstappen et al.   ANNALS OF THE RHEUMATIC DISEASES

Smokers in early axial spondyloarthritis have earlier disease onset, more disease activity, inflammation and damage, and poorer function and health-related quality of life: results from the DESIR cohort

(2011) Ho Yin Chung et al.   ANNALS OF THE RHEUMATIC DISEASES

Baseline radiographic damage, elevated acute-phase reactant levels, and cigarette smoking status predict spinal radiographic progression in early axial spondylarthritis

(2011) Denis Poddubnyy et al.   ARTHRITIS AND RHEUMATISM

Influence of methotrexate on infliximab pharmacokinetics and pharmacodynamics in ankylosing spondylitis

(2011) David Ternant et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The efficacy and safety of etanercept in patients with rheumatoid arthritis and spondyloarthropathy on hemodialysis

(2011) Soner Senel et al.   CLINICAL RHEUMATOLOGY

Home-based exercise therapy in patients with ankylosing spondylitis: effects on pain, mobility, disease activity, quality of life, and respiratory functions

(2011) Ebru Aytekin et al.   CLINICAL RHEUMATOLOGY

Similarities and differences between spondyloarthritis in Asia and other parts of the world

(2011) Shengli Zhang et al.   CURRENT OPINION IN RHEUMATOLOGY

Bilateral synchronous total hip arthroplasty for ankylosed hips

(2011) He Bangjian et al.   INTERNATIONAL ORTHOPAEDICS

GRADE guidelines: 3. Rating the quality of evidence

(2011) Howard Balshem et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Detection of infliximab in breast milk of nursing mothers with inflammatory bowel disease

(2011) Shomron Ben-Horin et al.   Journal of Crohns & Colitis

Therapeutic infliximab drug level in a child born to a woman with ulcerative colitis treated until gestation week 31

(2011) Casper Steenholdt et al.   Journal of Crohns & Colitis

Prospective study of reactivation of hepatitis B virus in patients with rheumatoid arthritis who received immunosuppressive therapy: evaluation of both HBsAg-positive and HBsAg-negative cohorts

(2011) Akihiro Tamori et al.   JOURNAL OF GASTROENTEROLOGY

Health and health-care systems in southeast Asia: diversity and transitions

(2011) Virasakdi Chongsuvivatwong et al.   LANCET

Past hepatitis B virus infection in rheumatoid arthritis patients receiving biological and/or nonbiological disease-modifying antirheumatic drugs

(2011) Shunsuke Mori   Modern Rheumatology

Persistent clinical efficacy and safety of infliximab in ankylosing spondylitis after 8 years--early clinical response predicts long-term outcome

(2011) X. Baraliakos et al.   RHEUMATOLOGY

Safety of anti-tumour necrosis factor agents in patients with chronic hepatitis C infection: a systematic review

(2011) A. M. G. Brunasso et al.   RHEUMATOLOGY

Infliximab in ankylosing spondylitis: alone or in combination with methotrexate? A pharmacokinetic comparative study

(2011) Denis Mulleman et al.   ARTHRITIS RESEARCH & THERAPY

EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases

(2010) S. van Assen et al.   ANNALS OF THE RHEUMATIC DISEASES

Measuring Multiple Etanercept Levels in the Breast Milk of a Nursing Mother with Rheumatoid Arthritis

(2010) S. KEELING et al.   JOURNAL OF RHEUMATOLOGY

Better short-term clinical response to etanercept in Chinese than Caucasian patients with active ankylosing spondylitis

(2010) Chung-Tei Chou et al.   Modern Rheumatology

Etanercept concentrations in maternal serum, umbilical cord serum, breast milk and child serum during breastfeeding

(2010) B. G. Berthelsen et al.   RHEUMATOLOGY

Efficacy and safety of adalimumab in a patient with ankylosing spondylitis on peritoneal dialysis

(2010) Senol Kobak   RHEUMATOLOGY INTERNATIONAL

Quality of life in patients with ankylosing spondylitis: relationships with spinal mobility, disease activity and functional status

(2010) Oya Özdemir   RHEUMATOLOGY INTERNATIONAL

Etanercept during pregnancy and lactation in a patient with rheumatoid arthritis: drug levels in maternal serum, cord blood, breast milk and the infant's serum

(2009) A Murashima et al.   ANNALS OF THE RHEUMATIC DISEASES

The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection

(2009) M Rudwaleit et al.   ANNALS OF THE RHEUMATIC DISEASES

Analysis of uveitis rates across all etanercept ankylosing spondylitis clinical trials

(2009) J Sieper et al.   ANNALS OF THE RHEUMATIC DISEASES

Adalimumab Level in Breast Milk of a Nursing Mother

(2009) Shomron Ben–Horin et al.   Clinical Gastroenterology and Hepatology

The Effect(s) of a Six-Week Home-Based Exercise Program on the Respiratory Muscle and Functional Status in Ankylosing Spondylitis

(2009) Ozgur Ortancil et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Hip Resurfacing Arthroplasty for Ankylosing Spondylitis

(2009) Jia Li et al.   JOURNAL OF ARTHROPLASTY

Absence of Infliximab in Infants and Breast Milk From Nursing Mothers Receiving Therapy for Crohnʼs Disease Before and After Delivery

(2009) Sunanda Kane et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Possible Reactivation of Potential Hepatitis B Virus Occult Infection by Tumor Necrosis Factor-  Blocker in the Treatment of Rheumatic Diseases

(2009) Y. J. KIM et al.   JOURNAL OF RHEUMATOLOGY

Etanercept in the Longterm Treatment of Patients With Ankylosing Spondylitis

(2009) B. DIJKMANS et al.   JOURNAL OF RHEUMATOLOGY

Spondyloarthritis Is Associated with Poor Function and Physical Health-Related Quality of Life

(2009) J. A. SINGH et al.   JOURNAL OF RHEUMATOLOGY

Clinical relevance of C-reactive protein in ankylosing spondylitis and evaluation of the NSAIDs/coxibs' treatment effect on C-reactive protein

(2009) M. Benhamou et al.   RHEUMATOLOGY

A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis

(2009) Anna Rita Giardina et al.   RHEUMATOLOGY INTERNATIONAL

Adalimumab effectiveness for the treatment of ankylosing spondylitis is maintained for up to 2 years: long-term results from the ATLAS trial

(2008) D van der Heijde et al.   ANNALS OF THE RHEUMATIC DISEASES

Adalimumab effectively reduces the rate of anterior uveitis flares in patients with active ankylosing spondylitis: results of a prospective open-label study

(2008) M Rudwaleit et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of golimumab in patients with ankylosing spondylitis: Results of a randomized, double-blind, placebo-controlled, phase III trial

(2008) Robert D. Inman et al.   ARTHRITIS AND RHEUMATISM

Primary Cementless Total Hip Arthroplasty for Bony Ankylosis in Patients with Ankylosing Spondylitis

(2008) Surya Bhan et al.   JOURNAL OF ARTHROPLASTY

Short-term efficacy of combination methotrexate and infliximab in patients with ankylosing spondylitis: a clinical and magnetic resonance imaging correlation

(2008) E. K. Li et al.   RHEUMATOLOGY

Is infliximab safe to use while breastfeeding?

(2008) Joel Z Stengel et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Going from evidence to recommendations

(2008) Gordon H Guyatt et al.   BMJ-British Medical Journal

Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial

(2007) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY