Tomentosin Displays Anti-Carcinogenic Effect in Human Osteosarcoma MG-63 Cells via the Induction of Intracellular Reactive Oxygen Species

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents

(2018) Malgorzata Bajor et al.   BRITISH JOURNAL OF CANCER

Phenylarsine oxide (PAO) induces apoptosis in HepG2 cells via ROS-mediated mitochondria and ER-stress dependent signaling pathways

(2017) Ping Huang et al.   Metallomics

Plumbagin induces apoptosis in human osteosarcoma through ROS generation, endoplasmic reticulum stress and mitochondrial apoptosis pathway

(2017) Chia-Chia Chao et al.   Molecular Medicine Reports

Peroxiredoxin-1 promotes cell proliferation and metastasis through enhancing Akt/mTOR in human osteosarcoma cells

(2017) An-Lie Cai et al.   Oncotarget

Genistein induces apoptosis by down-regulating thioredoxin-1 in human hepatocellular carcinoma SNU-449 cells

(2016) Taylor Roh et al.   FOOD AND CHEMICAL TOXICOLOGY

Tomentosin Induces Telomere Shortening and Caspase-Dependant Apoptosis in Cervical Cancer Cells

(2016) Nawel Merghoub et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Peroxiredoxin 1 has an anti-apoptotic role via apoptosis signal-regulating kinase 1 and p38 activation in mouse models with oral precancerous lesions

(2016) JIANFEI ZHANG et al.   Oncology Letters

Nimbolide Induces ROS-Regulated Apoptosis and Inhibits Cell Migration in Osteosarcoma

(2015) Ju-Fang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hesperetin Induces Apoptosis in Breast Carcinoma by Triggering Accumulation of ROS and Activation of ASK1/JNK Pathway

(2015) Shreyasi Palit et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Osteosarcoma: Current Treatment and a Collaborative Pathway to Success

(2015) Michael S. Isakoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial

(2015) Giovanni Grignani et al.   LANCET ONCOLOGY

Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study

(2015) H-Y Li et al.   Cell Death & Disease

Peroxiredoxin 1 suppresses apoptosis via regulation of the apoptosis signal-regulating kinase 1 signaling pathway in human oral leukoplakia

(2015) MIN ZHANG et al.   Oncology Letters

Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications

(2015) See-Hyoung Park et al.   Oncotarget

Overexpression or Silencing of FOXO3a Affects Proliferation of Endothelial Progenitor Cells and Expression of Cell Cycle Regulatory Proteins

(2014) Tiantian Sang et al.   PLoS One

Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

(2013) Eva-Maria Hanschmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Osteosarcoma treatment – Where do we stand? A state of the art review

(2013) Anja Luetke et al.   CANCER TREATMENT REVIEWS

Lapatinib induces p27Kip1-dependent G₁ arrest through both transcriptional and post-translational mechanisms

(2013) Lin Tang et al.   CELL CYCLE

Effects of Endothelial Progenitor Cell-Derived Microvesicles on Hypoxia/Reoxygenation-Induced Endothelial Dysfunction and Apoptosis

(2013) Jinju Wang et al.   Oxidative Medicine and Cellular Longevity

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

APRIL Binding to BCMA Activates a JNK2-FOXO3-GADD45 Pathway and Induces a G2/M Cell Growth Arrest in Liver Cells

(2012) G. Notas et al.   JOURNAL OF IMMUNOLOGY

Casticin induces growth suppression and cell cycle arrest through activation of FOXO3a in hepatocellular carcinoma

(2012) LIHUA HE et al.   ONCOLOGY REPORTS

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells

(2010) Wen-Wen Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Peroxiredoxin 1 Stimulates Secretion of Proinflammatory Cytokines by Binding to TLR4

(2009) J. R. Riddell et al.   JOURNAL OF IMMUNOLOGY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE

Induction of G2/M arrest and apoptosis by sesquiterpene lactones in human melanoma cell lines

(2007) Sharon Rozenblat et al.   BIOCHEMICAL PHARMACOLOGY