Telomerase Impinges on the Cellular Response to Oxidative Stress Through Mitochondrial ROS-Mediated Regulation of Autophagy
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Title
Telomerase Impinges on the Cellular Response to Oxidative Stress Through Mitochondrial ROS-Mediated Regulation of Autophagy
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 6, Pages 1509
Publisher
MDPI AG
Online
2019-03-27
DOI
10.3390/ijms20061509
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Note: Only part of the references are listed.- Protein encoded in human telomerase RNA is involved in cell protective pathways
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- The Major Reverse Transcriptase-Incompetent Splice Variant of the Human Telomerase Protein Inhibits Telomerase Activity but Protects from Apoptosis
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- Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis
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- UVC-Induced Mitochondrial Degradation via Autophagy Correlates with mtDNA Damage Removal in Primary Human Fibroblasts
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- Human telomerase represses ROS-dependent cellular responses to Tumor Necrosis Factor-α without affecting NF-κB activation
- (2011) Marina Mattiussi et al. CELLULAR SIGNALLING
- Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria
- (2011) Nilesh K. Sharma et al. NUCLEIC ACIDS RESEARCH
- A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction
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- hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer Cells
- (2010) I. R. Indran et al. CANCER RESEARCH
- Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From Damage
- (2009) Judith Haendeler et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress
- (2008) S. Ahmed et al. JOURNAL OF CELL SCIENCE
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