Transcription Factors in the Development and Function of Group 2 Innate Lymphoid Cells

Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation

(2019) Chizuko Miyamoto et al.   Nature Communications

Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors

(2018) Mari Tenno et al.   JOURNAL OF EXPERIMENTAL MEDICINE

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense

(2018) Yuefeng Huang et al.   SCIENCE

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

PD-1 regulates KLRG1+group 2 innate lymphoid cells

(2017) Samuel Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation

(2017) Antonia Wallrapp et al.   NATURE

The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation

(2017) Christoph S. N. Klose et al.   NATURE

Neuronal regulation of type 2 innate lymphoid cells via neuromedin U

(2017) Vânia Cardoso et al.   NATURE

Alternative activation generates IL-10 producing type 2 innate lymphoid cells

(2017) Corey R. Seehus et al.   Nature Communications

A shared Runx1-bound Zbtb16 enhancer directs innate and innate-like lymphoid lineage development

(2017) Ai-Ping Mao et al.   Nature Communications

Allergen-Experienced Group 2 Innate Lymphoid Cells Acquire Memory-like Properties and Enhance Allergic Lung Inflammation

(2016) Itziar Martinez-Gonzalez et al.   IMMUNITY

Adipose-Resident Group 1 Innate Lymphoid Cells Promote Obesity-Associated Insulin Resistance

(2016) Timothy E. O’Sullivan et al.   IMMUNITY

The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2

(2016) Erin C. Zook et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development of innate lymphoid cells

(2016) Erin C Zook et al.   NATURE IMMUNOLOGY

IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

(2016) Yoichiro Ohne et al.   NATURE IMMUNOLOGY

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

(2016) Christoph S N Klose et al.   NATURE IMMUNOLOGY

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

(2016) Jonathan S Silver et al.   NATURE IMMUNOLOGY

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

(2015) Min-Woo Lee et al.   CELL

Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells

(2015) Danielle Califano et al.   IMMUNITY

ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity

(2015) Hadi Maazi et al.   IMMUNITY

The RUNX complex: reaching beyond haematopoiesis into immunity

(2015) Dominic Chih-Cheng Voon et al.   IMMUNOLOGY

Group 2 innate lymphoid cells in disease

(2015) Timotheus Y. F. Halim   INTERNATIONAL IMMUNOLOGY

The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development

(2015) Yong Yu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bcl11b is essential for group 2 innate lymphoid cell development

(2015) Jennifer A. Walker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Restriction of Nonpermissive RUNX3 Protein Expression in T Lymphocytes by the Kozak Sequence

(2015) Byungil Kim et al.   JOURNAL OF IMMUNOLOGY

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

(2015) Jakob von Moltke et al.   NATURE

Runx3 specifies lineage commitment of innate lymphoid cells

(2015) Takashi Ebihara et al.   NATURE IMMUNOLOGY

Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses

(2015) Timotheus Y F Halim et al.   NATURE IMMUNOLOGY

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow

(2015) Qi Yang et al.   NATURE IMMUNOLOGY

Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets

(2015) Michelle L Robinette et al.   NATURE IMMUNOLOGY

Innate lymphoid cells in the initiation, regulation and resolution of inflammation

(2015) Gregory F Sonnenberg et al.   NATURE MEDICINE

Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs

(2015) G. Gasteiger et al.   SCIENCE

Group 2 Innate Lymphoid Cells in Health and Disease

(2015) Brian S. Kim et al.   Cold Spring Harbor Perspectives in Biology

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

The Transcription Factor GATA3 Is Critical for the Development of All IL-7Rα-Expressing Innate Lymphoid Cells

(2014) Ryoji Yagi et al.   IMMUNITY

CX3CR1+mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22

(2014) Randy S. Longman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow

(2014) Cécile Daussy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcription Factor Runx3 Regulates Interleukin-15-Dependent Natural Killer Cell Activation

(2014) D. Levanon et al.   MOLECULAR AND CELLULAR BIOLOGY

A committed precursor to innate lymphoid cells

(2014) Michael G. Constantinides et al.   NATURE

IL-25-responsive, lineage-negative KLRG1hi cells are multipotential ‘inflammatory’ type 2 innate lymphoid cells

(2014) Yuefeng Huang et al.   NATURE IMMUNOLOGY

The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor

(2014) Xiaofei Yu et al.   eLife

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

(2014) Dorothy K Sojka et al.   eLife

T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment

(2013) Joel Crespo et al.   CURRENT OPINION IN IMMUNOLOGY

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

Transcription factor Runx2 controls the development and migration of plasmacytoid dendritic cells

(2013) Catherine M. Sawai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type 2 innate lymphoid cells control eosinophil homeostasis

(2013) Jesse C. Nussbaum et al.   NATURE

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1

(2013) Chauncey J Spooner et al.   NATURE IMMUNOLOGY

Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells

(2013) R. G. J. Klein Wolterink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TSLP Elicits IL-33-Independent Innate Lymphoid Cell Responses to Promote Skin Inflammation

(2013) B. S. Kim et al.   Science Translational Medicine

The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid Cells

(2012) Thomas Hoyler et al.   IMMUNITY

Retinoic-Acid-Receptor-Related Orphan Nuclear Receptor Alpha Is Required for Natural Helper Cell Development and Allergic Inflammation

(2012) Timotheus Y.F. Halim et al.   IMMUNITY

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

(2012) Stanislav Pantelyushin et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of the Aryl Hydrocarbon Receptor in Controlling Maintenance and Functional Programs of RORγt+ Innate Lymphoid Cells and Intraepithelial Lymphocytes

(2012) Elina A. Kiss et al.   Frontiers in Immunology

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

(2011) Ya-Jen Chang et al.   NATURE IMMUNOLOGY

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation

(2011) Christoph Wilhelm et al.   NATURE IMMUNOLOGY

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

(2011) Jacob S Lee et al.   NATURE IMMUNOLOGY

Translation regulation of Runx3

(2010) Karen Rae Bone et al.   BLOOD CELLS MOLECULES AND DISEASES

The Transcription Factor GATA3 Actively Represses RUNX3 Protein-Regulated Production of Interferon-γ

(2010) Ryoji Yagi et al.   IMMUNITY

T-cell exhaustion: characteristics, causes and conversion

(2010) John S. Yi et al.   IMMUNOLOGY

Runx1/Cbf 2 Complexes Are Required for Lymphoid Tissue Inducer Cell Differentiation at Two Developmental Stages

(2010) M. Tachibana et al.   JOURNAL OF IMMUNOLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

(2010) Shinichiro Sawa et al.   SCIENCE

Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells

(2009) Akihiko Kitoh et al.   IMMUNITY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells

(2008) Fuping Zhang et al.   NATURE IMMUNOLOGY