Article
Urology & Nephrology
Jordan Nasri, Flora Barthe, Sneha Parekh, Parita Ratnani, Adriana M. Pedraza, Vinayak G. Wagaskar, Jonathan Olivier, Arnauld Villers, Ash Tewari
Summary: This study developed and validated a prediction model to assess the risk of adverse pathology outcome in low-risk prostate cancer patients. The model showed good accuracy in predicting adverse pathology outcomes and could aid in treatment decision-making for this patient population.
Article
Oncology
P. Travis Courtney, Rishi Deka, Nikhil Kotha, Daniel R. Cherry, Mia A. Salans, Tyler J. Nelson, Abhishek Kumar, Elaine Luterstein, Anthony T. Yip, Vinit Nalawade, J. Kellogg Parsons, A. Karim Kader, Tyler F. Stewart, Brent S. Rose
Summary: Outcomes were similar for African American and White men treated for low-intermediate-risk prostate cancer with active surveillance in the Veterans Affairs Health System.
Article
Urology & Nephrology
Kevin Shee, Janet E. Cowan, Ashwin Balakrishnan, Domenique Escobar, Kevin Chang, Samuel L. Washington, Hao G. Nguyen, Katsuto Shinohara, Matthew R. Cooperberg, Peter R. Carroll
Summary: Although the American Urological Association and European Association of Urology do not use the very low-risk (VLR) subcategory for low-risk prostate cancer (PCa), the National Comprehensive Cancer Network (NCCN) still maintains this classification. However, a study found that the NCCN VLR criteria are less applicable in the era of imaging-targeted prostate biopsies, and the Cancer of the Prostate Risk Assessment (CAPRA) score may be a better tool for risk stratification in men on active surveillance. The study suggests that the VLR criteria should be reevaluated for its relevance in the modern era.
Article
Multidisciplinary Sciences
Hwanik Kim, Gyoohwan Jung, Jin Hyuck Kim, Seok-Soo Byun, Sung Kyu Hong
Summary: PHI can predict GS upgrading in ISUP GG 1 & 2, in conjunction with PIRADS lesions >= 4. PHI alone can also evaluate the likelihood of high-risk PCa after surgery.
SCIENTIFIC REPORTS
(2021)
Article
Urology & Nephrology
Francesco Chierigo, Mike Wenzel, Christoph Wuernschimmel, Rocco Simone Flammia, Benedikt Horlemann, Zhe Tian, Fred Saad, Felix K. H. Chun, Markus Graefen, Michele Gallucci, Shahrokh F. Shariat, Guglielmo Mantica, Marco Borghesi, Nazareno Suardi, Carlo Terrone, Pierre Karakiewicz
Summary: This study compared the survival rates between hormone therapy and hormone therapy plus chemotherapy in high-risk patients. The results showed that hormone therapy had a better cancer-specific survival rate in the overall NCCN high-risk cohort and the JH high-risk and very high-risk subgroup.
JOURNAL OF UROLOGY
(2022)
Article
Endocrinology & Metabolism
Susan C. Pitt, Nan Yang, Megan C. Saucke, Nicholas Marka, Bret Hanlon, Kristin L. Long, Alexandria D. McDow, J. P. Brito, Benjamin R. Roman
Summary: The study aimed to understand factors associated with the adoption of active surveillance (AS) for thyroid cancer. Results showed that nonadopters were less likely to work in academic settings, see a high number of thyroid cancer patients, be aware of AS, use applicable guidelines, have resources or motivation for AS, while adopters were more likely to have awareness, resources, and motivation for AS.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Urology & Nephrology
Valentin H. Meissner, Mira Woll, Donna P. Ankerst, Stefan Schiele, Juergen E. Gschwend, Kathleen Herkommer
Summary: The study found that patients at favorable intermediate-risk had slightly worse pathological and long-term outcomes compared to low-risk patients, but the difference compared to unfavorable intermediate-risk patients was significant. This emphasizes AS as a possible treatment strategy for well-counseled patients in this group.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Multidisciplinary Sciences
Wei-Hsin Chen, Yu Khun Lee, Hann-Chorng Kuo, Jen-Hung Wang, Yuan-Hong Jiang
Summary: This study examined the outcomes of robot-assisted radical prostatectomy (RaRP) in high-risk and very high-risk prostate cancer patients. The results showed that high-risk/very high-risk patients without adjuvant treatment had worse biochemical recurrence-free survival compared to those with adjuvant treatment. However, the combination of RaRP and adjuvant treatment resulted in comparable biochemical recurrence-free survival for high-risk/very high-risk patients and below high-risk patients. Additionally, high-risk/very high-risk patients had higher rates of stress urinary incontinence at postoperative week 1 and month 1 compared to below high-risk patients, but there was no significant difference in incontinence rates between the two groups from postoperative 3 months to 12 months.
Article
Urology & Nephrology
Helen Y. Hougen, Oleksii A. Iakymenko, Sanoj Punnen, Chad R. Ritch, Bruno Nahar, Dipen J. Parekh, Oleksandr N. Kryvenko, Mark L. Gonzalgo
Summary: This study investigated the outcomes of radical prostatectomy in Hispanic men with prostate cancer. The results showed that Hispanic men had similar rates of upgrading and adverse pathology outcomes as non-Hispanic white men. Race/ethnicity was not found to predict upgrading or worse oncologic outcomes after prostatectomy.
WORLD JOURNAL OF UROLOGY
(2022)
Article
Urology & Nephrology
Lars Bjornebo, Henrik Olsson, Tobias Nordstrom, Fredrik Jaderling, Henrik Gronberg, Martin Eklund, Anna Lantz
Summary: The study aimed to evaluate clinical variables, including MRI, for predicting adverse pathology at RP in men initially enrolled in AS. Age, clinical T-stage, PSA, and PI-RADS score were found to be significantly associated with adverse pathology at RP.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Oncology
Kimberly D. Miller, Ana P. Ortiz, Paulo S. Pinheiro, Priti Bandi, Adair Minihan, Hannah E. Fuchs, Dinorah Martinez Tyson, Guillermo Tortolero-Luna, Stacey A. Fedewa, Ahmedin M. Jemal, Rebecca L. Siegel
Summary: The Hispanic/Latino population accounts for 18% of the total population in the continental United States and Hawaii. While their cancer incidence and mortality rates are lower compared to non-Hispanic Whites, they have higher rates of certain types of cancer such as liver and stomach cancer, indicating the need for improved cancer prevention strategies.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Article
Health Care Sciences & Services
Barak Rosenzweig, Rennen Haramaty, Tima Davidson, Alon Lazarovich, Asaf Shvero, Miki Haifler, Jonathan Gal, Shay Golan, Sagi Shpitzer, Azik Hoffman, Omri Nativ, Yuval Freifeld, Rani Zreik, Zohar A. Dotan
Summary: This study evaluated a unique subpopulation of RP candidates with negative PSMA PET/CT scans and found that misleading results can occur. However, the study also discovered a correlation between PSMA uptake and disease aggressiveness.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Oncology
Richard M. Hoffman, Sarah L. Mott, Bradley D. McDowell, Sonia T. Anand, Kenneth G. Nepple
Summary: The study observed an increasing trend in the uptake of expectant management for low-risk prostate cancer over time, although a significant proportion of patients still opted for active treatment. A large number of patients who chose expectant management did not initiate active surveillance monitoring, even among those with a life expectancy exceeding 10 years, indicating that watchful waiting was being employed in managing these patients. Active surveillance monitoring was associated with a higher likelihood of switching to active treatment, implying that treatment decisions were likely based on cancer progression.
PROSTATE CANCER AND PROSTATIC DISEASES
(2022)
Article
Urology & Nephrology
Benedikt Hoeh, Jan L. Hohenhorst, Rocco Flammia, Benedikt Horlemann, Gabriele Sorce, Francesco Chierigo, Zhe Tian, Fred Saad, Markus Graefen, Michele Gallucci, Alberto Briganti, Carlo Terrone, Shahrokh F. Shariat, Luis A. Kluth, Andreas Becker, Felix K. H. Chun, Pierre Karakiewicz
Summary: The study aimed to compare cancer-specific mortality rates in Hispanic/Latino prostate cancer patients based on different treatment types (radical prostatectomy or external beam radiotherapy). The results indicated a potential benefit of radical prostatectomy over external beam radiotherapy in high-risk patients, but this difference was no longer statistically significant after adjusting for patient and tumor characteristics.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2022)
Article
Urology & Nephrology
Joel Berends, Ajith Dupati, John Dibianco, Arvin K. George
Summary: Focal therapy has emerged as a potential alternative to active surveillance or definitive treatment for carefully selected men with low-risk prostate cancer, offering durable oncological benefit while preserving quality of life. This approach challenges the dichotomous options currently presented to men with low-risk cancer, emphasizing the importance of not only survival but also preservation of sexual/urinary function as meaningful measures of success.
JOURNAL OF ENDOUROLOGY
(2021)
Article
Urology & Nephrology
Chad R. Ritch, Raymond Balise, Nachiketh Soodana Prakash, David Alonzo, Katherine Almengo, Mahmoud Alameddine, Vivek Venkatramani, Sanoj Punnen, Dipen J. Parekh, Mark L. Gonzalgo
Article
Urology & Nephrology
Chad R. Ritch, Nachiketh Soodana-Prakash, Nicola Pavan, Raymond R. Balise, Maria Camila Velasquez, Mahmoud Alameddine, Desmond Y. Adamu, Sanoj Punnen, Dipen J. Parekh, Mark L. Gonzalgo
Article
Oncology
Vivek Venkatramani, Tulay Koru-Sengul, Feng Miao, Bruno Nahar, Nachiketh Soodana Prakash, Sanjaya Swain, Sanoj Punnen, Chad Ritch, Mark Gonzalgo, Dipen Parekh
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2018)
Article
Urology & Nephrology
Maria C. Velasquez, Felix M. Chinea, Deukwoo Kwon, Nachiketh Soodana Prakash, Marcelo P. Barboza, Mark L. Gonzalgo, Chad R. Ritch, Alan Pollack, Dipen J. Parekh, Sanoj Punnen
Article
Urology & Nephrology
Mahmoud Alameddine, Zhobin Moghadamyeghaneh, Ali Yusufali, Alexa Marie Collazo, Joshua S. Jue, Ian Zheng, Mahmoud Morsi, Nachiketh Soodana Prakash, Javier Gonzalez
CURRENT UROLOGY REPORTS
(2018)
Article
Oncology
Nachiketh Soodana-Prakash, Tulay Koru-Sengul, Feng Miao, Diana M. Lopategui, Luis F. Savio, Kevin J. Moore, Taylor A. Johnson, Mahmoud Alameddine, Marcelo Panizzutti Barboza, Dipen J. Parekh, Sanoj Punnen, Mark L. Gonzalgo, Chad R. Ritch
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2018)
Article
Multidisciplinary Sciences
Yohann Tschudi, Alan Pollack, Sanoj Punnen, John C. Ford, Yu-Cherng Chang, Nachiketh Soodana-Prakash, Adrian L. Breto, Deukwoo Kwon, Felipe Munera, Matthew C. Abramowitz, Oleksandr N. Kryvenko, Radka Stoyanova
SCIENTIFIC REPORTS
(2018)
Editorial Material
Hematology
Kirill A. Lyapichev, M. James You
Letter
Hematology
Kirill A. Lyapichev, Narittee Sukswai, Sergej Konoplev, Joseph D. Khoury
ANNALS OF HEMATOLOGY
(2019)
Article
Urology & Nephrology
Chad R. Ritch, Maria C. Velasquez, Deukwoo Kwon, Maria F. Becerra, Nachiketh Soodana-Prakash, Venkatasai S. Atluri, Katherine Almengo, Mahmoud Alameddine, Omer Kineish, Bruce R. Kava, Sanoj Punnen, Dipen J. Parekh, Mark L. Gonzalgo
JOURNAL OF UROLOGY
(2020)
Article
Urology & Nephrology
Abhishek Bhat, Deukwoo Kwon, Nachiketh Soodana-Prakash, Ali Mouzannar, Sanoj Punnen, Mark L. Gonzalgo, Dipen J. Parekh, Chad R. Ritch
Summary: The study aimed to determine the optimal cystoscopic interval for intermediate risk, nonmuscle invasive bladder cancer. Results showed that moderate intensity (6-month) surveillance intervals in this patient population allow for timely detection without compromising oncological outcomes, and are less costly with fewer cystoscopies compared to high intensity (3-month) intervals.
JOURNAL OF UROLOGY
(2021)
Article
Urology & Nephrology
Mahmoud Alameddine, Tulay Koru-Sengul, Kevin J. Moore, Feng Miao, Luis Felipe Savio, Bruno Nahar, Nachiketh Soodana Prakash, Vivek Venkatramani, Joshua S. Jue, Sanoj Punnen, Dipen J. Parekh, Chad R. Ritch, Mark L. Gonzalgo
EUROPEAN UROLOGY FOCUS
(2019)
Article
Andrology
John M. Masterson, Nachiketh Soodana-Prakash, Amir S. Patel, Atil Y. Kargi, Ranjith Ramasamy
WORLD JOURNAL OF MENS HEALTH
(2019)
Review
Andrology
Nachiketh Soodana-Prakash, Radka Stoyanova, Abhishek Bhat, Maria C. Velasquez, Omer E. Kineish, Alan Pollack, Dipen J. Parekh, Sanoj Punnen
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2018)
Review
Medicine, General & Internal
Arthy Yoga, Kirill A. Lyapichev, Donghwa Baek, Carmen R. Gomez-Fernandez
AMERICAN JOURNAL OF CASE REPORTS
(2018)