Myristica fragrans Kernels Prevent Paracetamol-Induced Hepatotoxicity by Inducing Anti-Apoptotic Genes and Nrf2/HO-1 Pathway

Phytochemical investigation on Myristica fragrans stem bark

(2018) Sajin K. Francis et al.   NATURAL PRODUCT RESEARCH

Evaluation of the Protective Effect of Olive Leaf Extract on Cisplatin-Induced Testicular Damage in Rats

(2018) Rafa S. Almeer et al.   Oxidative Medicine and Cellular Longevity

Silymarin prevents acetaminophen-induced hepatotoxicity in mice

(2018) Zuzana Papackova et al.   PLoS One

The potential hepatoprotective effect of royal jelly against cadmium chloride-induced hepatotoxicity in mice is mediated by suppression of oxidative stress and upregulation of Nrf2 expression

(2018) Rafa S. Almeer et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective role of heme oxygenase-1 in fatty liver ischemia–reperfusion injury

(2018) Shaowei Li et al.   Medical Molecular Morphology

Ziziphus spina-christi leaf extract ameliorates schistosomiasis liver granuloma, fibrosis, and oxidative stress through downregulation of fibrinogenic signaling in mice

(2018) Rafa S. Almeer et al.   PLoS One

Recent progress and challenges in screening and characterization of UGT1A1 inhibitors

(2018) Xia Lv et al.   Acta Pharmaceutica Sinica B

Comparative analysis of the protective effects of curcumin and N-acetyl cysteine against paracetamol-induced hepatic, renal, and testicular toxicity in Wistar rats

(2017) Zeynab Kh El-Maddawy et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells

(2017) Lenka Roubalová et al.   FITOTERAPIA

Monodora myristica (African nutmeg) modulates redox homeostasis and alters functional chemistry in sickled erythrocytes

(2017) OL Erukainure et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Cytoprotective effects of myristicin against hypoxia-induced apoptosis and endoplasmic reticulum stress in rat dorsal root ganglion neurons

(2017) Quanlai Zhao et al.   Molecular Medicine Reports

Long-term acetaminophen treatment induced liver fibrosis in mice and the involvement of Egr-1

(2017) Qingyun Bai et al.   TOXICOLOGY

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice

(2017) Hiroki Yoshioka et al.   Environmental Health and Preventive Medicine

Effects of luteolin and quercetin 3-β- d -glucoside identified from Passiflora subpeltata leaves against acetaminophen induced hepatotoxicity in rats

(2016) Saravanan Shanmugam et al.   BIOMEDICINE & PHARMACOTHERAPY

New acyclic bis phenylpropanoid and neolignans, from Myristica fragrans Houtt., exhibiting PARP-1 and NF-κB inhibitory effects

(2016) Ulyana Muñoz Acuña et al.   FOOD CHEMISTRY

Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?

(2016) Subrata Kumar Biswas   Oxidative Medicine and Cellular Longevity

Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury

(2016) Yuan Gao et al.   Proteomics Clinical Applications

Hepatocyte-protective effect of nectandrin B, a nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK phosphorylation and AMPK-dependent inhibition of GSK-3β

(2016) Jae-Sook Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nutmeg oil alleviates chronic inflammatory pain through inhibition of COX-2 expression and substance P release in vivo

(2016) Wei Kevin Zhang et al.   Food & Nutrition Research

Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

(2016) Kuo Du et al.   Redox Biology

Bilirubin Binding to PPARα Inhibits Lipid Accumulation

(2016) David E. Stec et al.   PLoS One

Indigofera oblongifolia Prevents Lead Acetate-Induced Hepatotoxicity, Oxidative Stress, Fibrosis and Apoptosis in Rats

(2016) Ahmed E. Abdel Moneim   PLoS One

Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats

(2015) Attalla Farag El-Kott et al.   CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL

Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity

(2015) Kuo Du et al.   FOOD AND CHEMICAL TOXICOLOGY

Amelioration of Paracetamol-Induced Hepatotoxicity in Rat by the Administration of Methanol Extract ofMuntingia calaburaL. Leaves

(2014) N. D. Mahmood et al.   Biomed Research International

A perspective on the epidemiology of acetaminophen exposure and toxicity in the United States

(2014) Marissa Blieden et al.   Expert Review of Clinical Pharmacology

Acetaminophen-related Hepatotoxicity

(2013) Chalermrat Bunchorntavakul et al.   Clinics in Liver Disease

The Neuroprotective Effects of Purslane (Portulaca oleracea) on Rotenone- Induced Biochemical Changes and Apoptosis in Brain of Rat

(2013) Ahmed Abdel Moneim   CNS & Neurological Disorders-Drug Targets

Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21

(2013) Terry D. Hinds et al.   Obesity

Curcumin protects against acetaminophen-induced apoptosis in hepatic injury

(2013) Gang Li   WORLD JOURNAL OF GASTROENTEROLOGY

Chemical Composition and Antioxidant Activity of Essential Oil and Oleoresins of Nutmeg (Myristica fragransHoutt.) Fruits

(2012) I.P.S. Kapoor et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

Acetaminophen Induces Human Neuroblastoma Cell Death through NFKB Activation

(2012) Inmaculada Posadas et al.   PLoS One

Depletion of activated hepatic stellate cell correlates with severe liver damage and abnormal liver regeneration in acetaminophen-induced liver injury

(2011) K. Shen et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Antioxidants in aqueous extract of Myristica fragrans (Houtt.) suppress mitosis and cyclophosphamide-induced chromosomal aberrations in Allium cepa L. cells

(2011) Akeem Akinboro et al.   Journal of Zhejiang University-SCIENCE B

Anti-Inflammatory Effect of Myristicin on RAW 264.7 Macrophages Stimulated with Polyinosinic-Polycytidylic Acid

(2011) Ji Young Lee et al.   MOLECULES

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

Apoptogenic factors released from mitochondria

(2010) David L. Vaux   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of Mace and Nutmeg on Human Cytochrome P450 3A4 and 2C9 Activity

(2010) Yuka Kimura et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Modulation of Bax/Bcl-2 and caspases by probiotics during acetaminophen induced apoptosis in primary hepatocytes

(2010) S. Sharma et al.   FOOD AND CHEMICAL TOXICOLOGY

rhIL-1Ra reduces hepatocellular apoptosis in mice with acetaminophen-induced acute liver failure

(2010) Jianjun Hu et al.   LABORATORY INVESTIGATION

A new antioxidant from wild nutmeg

(2009) C.A. Calliste et al.   FOOD CHEMISTRY

Serum Bilirubin and Ferritin Levels Link Heme Oxygenase-1 Gene Promoter Polymorphism and Susceptibility to Coronary Artery Disease in Diabetic Patients

(2008) Y.-H. Chen et al.   DIABETES CARE