Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human

Porphyromonas gingivalis lipopolysaccharide induces pro-inflammatory adipokine secretion and oxidative stress by regulating Toll-like receptor-mediated signaling pathways and redox enzymes in adipocytes

(2017) Fanny Le Sage et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cholesterol crystals enhance TLR2- and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

(2017) Tania Køllgaard et al.   PLoS One

3LPS-binding protein and its interactions with P. gingivalis LPS modulate pro-inflammatory response and Toll-like receptor signaling in human oral keratinocytes

(2017) Pei-Hui Ding et al.   PLoS One

Toll-like receptors: promising therapeutic targets for inflammatory diseases

(2016) Asma Achek et al.   ARCHIVES OF PHARMACAL RESEARCH

Alveolar bone loss in relation to toll-like receptor 4 and 9 genotypes and Porphyromonas gingivalis carriage

(2016) U. K. Gursoy et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Links between atherosclerotic and periodontal disease

(2016) Dimitry A. Chistiakov et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide

(2016) Lili Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Periodontitis contributes to adipose tissue inflammation through the NF-B, JNK and ERK pathways to promote insulin resistance in a rat model

(2016) Yanli Huang et al.   MICROBES AND INFECTION

Human β-defensin 3 suppresses Porphyromonas gingivalis lipopolysaccharide-induced inflammation in RAW 264.7 cells and aortas of ApoE-deficient mice

(2016) Tianying Bian et al.   PEPTIDES

Lipopolysaccharides-Induced Suppression of Innate-Like B Cell Apoptosis Is Enhanced by CpG Oligodeoxynucleotide and Requires Toll-Like Receptors 2 and 4

(2016) Xiaoqian Yu et al.   PLoS One

Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies

(2016) Stavroula Ntoufa et al.   SEMINARS IN CANCER BIOLOGY

Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to P. gingivalis Lipopolysaccharide

(2016) Oleh Andrukhov et al.   PLoS One

Porphyromonas gingivalisStimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-κB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts

(2015) Ali Kassem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant polyphenol-rich extracts from the medicinal plants Antirhea borbonica, Doratoxylon apetalum and Gouania mauritiana protect 3T3-L1 preadipocytes against H2O2, TNFα and LPS inflammatory mediators by regulating the expression of superoxide dismutase and NF-κB genes

(2015) Méry Marimoutou et al.   Journal of Inflammation-London

Autotaxin Downregulates LPS-Induced Microglia Activation and Pro-Inflammatory Cytokines Production

(2014) Rana Awada et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Connection Between Periodontitis and Alzheimer’s Disease: Possible Roles of Microglia and Leptomeningeal Cells

(2014) Zhou Wu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Periodontitis as a Risk Factor of Atherosclerosis

(2014) Jirina Bartova et al.   Journal of Immunology Research

A Novel Class of Lipoprotein Lipase-Sensitive Molecules Mediates Toll-Like Receptor 2 Activation by Porphyromonas gingivalis

(2013) Sumita Jain et al.   INFECTION AND IMMUNITY

Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-κB Signal Transduction Cascade and Immuno-Inflammatory Response in Human Gingival Fibroblasts

(2013) Thanuja D. K. Herath et al.   PLoS One

Soluble HMGB1 Is a Novel Adipokine Stimulating IL-6 Secretion through RAGE Receptor in SW872 Preadipocyte Cell Line: Contribution to Chronic Inflammation in Fat Tissue

(2013) Brice Nativel et al.   PLoS One

Free Lipid A Isolated from Porphyromonas gingivalis Lipopolysaccharide Is Contaminated with Phosphorylated Dihydroceramide Lipids: Recovery in Diseased Dental Samples

(2011) Frank C. Nichols et al.   INFECTION AND IMMUNITY

The c-Jun N-Terminal Kinase Mediates the Induction of Oxidative Stress and Insulin Resistance by Palmitate and Toll-like Receptor 2 and 4 Ligands in 3T3-L1 Adipocytes

(2009) J. Davis et al.   HORMONE AND METABOLIC RESEARCH

Resilience to Bacterial Infection: Difference between Species Could Be Due to Proteins in Serum

(2009) H. Shaw Warren et al.   JOURNAL OF INFECTIOUS DISEASES

Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4

(2008) Yanghui Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY