Effect of environmental and pharmaceutical exposures on fetal testis development and function: a systematic review of human experimental data

Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental Systems

(2018) Pablo Hurtado-Gonzalez et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study

(2018) Edward Dere et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of environmental Bisphenol A exposures on germ cell development and Leydig cell function in the human fetal testis

(2018) Soria Eladak et al.   PLoS One

Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study

(2017) Djamilla Madelung Mogensen et al.   Environmental Health

Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants

(2017) Pierre Gaudriault et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Testicular organoids: a new model to study the testicular microenvironment in vitro?

(2017) João Pedro Alves-Lopes et al.   HUMAN REPRODUCTION UPDATE

Fetal Alcohol Spectrum Disorders: What Pediatric Providers Need to Know

(2017) Angela Nash et al.   Journal of Pediatric Health Care

A systematic review of maternal smoking during pregnancy and fetal measurements with meta-analysis

(2017) Miriam Abraham et al.   PLoS One

Analgesic use in pregnancy and male reproductive development

(2017) Pablo Hurtado-Gonzalez et al.   Current Opinion in Endocrinology Diabetes and Obesity

Ibuprofen results in alterations of human fetal testis development

(2017) Millissia Ben Maamar et al.   Scientific Reports

Human exposure to environmental contaminants and congenital anomalies: a critical review

(2016) Warren G. Foster et al.   CRITICAL REVIEWS IN TOXICOLOGY

Urine and serum biomonitoring of exposure to environmental estrogens I: Bisphenol A in pregnant women

(2016) Justin G. Teeguarden et al.   FOOD AND CHEMICAL TOXICOLOGY

Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants

(2016) B.G. Fisher et al.   HUMAN REPRODUCTION

The epidemiologic evidence linking prenatal and postnatal exposure to endocrine disrupting chemicals with male reproductive disorders: a systematic review and meta-analysis

(2016) Jens Peter Bonde et al.   HUMAN REPRODUCTION UPDATE

Testicular germ cell tumours

(2016) Ewa Rajpert-De Meyts et al.   LANCET

Analgesic use — prevalence, biomonitoring and endocrine and reproductive effects

(2016) David M. Kristensen et al.   Nature Reviews Endocrinology

Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility

(2016) Niels E. Skakkebaek et al.   PHYSIOLOGICAL REVIEWS

Bisphenol A and other phenols in human placenta from children with cryptorchidism or hypospadias

(2016) Mariana F. Fernández et al.   REPRODUCTIVE TOXICOLOGY

Timing of prenatal phthalate exposure in relation to genital endpoints in male newborns

(2016) A. J. Martino-Andrade et al.   Andrology

Human metabolism and excretion kinetics of aniline after a single oral dose

(2015) Hendrik Modick et al.   ARCHIVES OF TOXICOLOGY

Development of the follicular basement membrane during human gametogenesis and early folliculogenesis

(2015) A Heeren et al.   BMC DEVELOPMENTAL BIOLOGY

Prenatal Exposure to Phthalates and Anogenital Distance in Male Infants from a Low-Exposed Danish Cohort (2010–2012)

(2015) Tina Kold Jensen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Amniotic Fluid Phthalate Levels and Male Fetal Gonad Function

(2015) Morten Søndergaard Jensen et al.   EPIDEMIOLOGY

A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound

(2015) Soria Eladak et al.   FERTILITY AND STERILITY

First trimester phthalate exposure and anogenital distance in newborns

(2015) S. H. Swan et al.   HUMAN REPRODUCTION

Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model

(2015) Sander van den Driesche et al.   Science Translational Medicine

Aniline Is Rapidly Converted Into Paracetamol Impairing Male Reproductive Development

(2015) Jacob Bak Holm et al.   TOXICOLOGICAL SCIENCES

Serum Bisphenol A Level in Boys with Cryptorchidism: A Step to Male Infertility?

(2015) Marta Diana Komarowska et al.   International Journal of Endocrinology

Review: UK medicines likely to be affected by the proposed European Medicines Agency’s guidelines on phthalates

(2015) Lisa Jamieson et al.   BMC Pharmacology & Toxicology

An Investigation of the Endocrine-Disruptive Effects of Bisphenol A in Human and Rat Fetal Testes

(2015) Millissia Ben Maamar et al.   PLoS One

A negative correlation between insulin-like peptide 3 and bisphenol A in human cord blood suggests an effect of endocrine disruptors on testicular descent during fetal development

(2014) N. Chevalier et al.   HUMAN REPRODUCTION

Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

(2014) K. R. Kilcoyne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitous presence of paracetamol in human urine: sources and implications

(2014) Hendrik Modick et al.   REPRODUCTION

Antiandrogenic Mechanisms of Pesticides in Human LNCaP Prostate and H295R Adrenocortical Carcinoma Cells

(2014) Christina N. Robitaille et al.   TOXICOLOGICAL SCIENCES

Environmental exposure to the plasticizer 1,2-cyclohexane dicarboxylic acid, diisononyl ester (DINCH) in US adults (2000—2012)

(2013) Manori J. Silva et al.   ENVIRONMENTAL RESEARCH

Perinatal germ cell development and differentiation in the male marmoset (Callithrix jacchus): similarities with the human and differences from the rat

(2013) C. McKinnell et al.   HUMAN REPRODUCTION

A critical assessment of the endocrine susceptibility of the human testis to phthalates from fetal life to adulthood

(2013) Océane Albert et al.   HUMAN REPRODUCTION UPDATE

Paracetamol, Aspirin, and Indomethacin Induce Endocrine Disturbances in the Human Fetal Testis Capable of Interfering With Testicular Descent

(2013) Séverine Mazaud-Guittot et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Anogenital Distance or Digit Length Ratio as Measures of Fetal Androgen Exposure: Relationship to Male Reproductive Development and Its Disorders

(2013) Afshan Dean et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diethylstilboestrol Exposure Does Not Reduce Testosterone Production in Human Fetal Testis Xenografts

(2013) Rod T. Mitchell et al.   PLoS One

Prostaglandins, Masculinization and Its Disorders: Effects of Fetal Exposure of the Rat to the Cyclooxygenase Inhibitor- Indomethacin

(2013) Afshan Dean et al.   PLoS One

Mixtures of endocrine-disrupting contaminants induce adverse developmental effects in preweaning rats

(2013) Marta Axelstad et al.   REPRODUCTION

A new approach to synergize academic and guideline-compliant research: The CLARITY-BPA research program

(2013) Thaddeus T. Schug et al.   REPRODUCTIVE TOXICOLOGY

Differential Response to Abiraterone Acetate and Di-n-butyl Phthalate in an Androgen-Sensitive Human Fetal Testis Xenograft Bioassay

(2013) Daniel J. Spade et al.   TOXICOLOGICAL SCIENCES

In vitro - in vivo correlations for endocrine activity of a mixture of currently used pesticides

(2013) Camilla Taxvig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses

(2012) H. M. Koch et al.   ARCHIVES OF TOXICOLOGY

Human Fetal Testis Xenografts Are Resistant to Phthalate-Induced Endocrine Disruption

(2012) Nicholas E Heger et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Maternal Urinary Phthalates and Phenols and Male Genital Anomalies

(2012) Cécile Chevrier et al.   EPIDEMIOLOGY

Metformin exposure affects human and mouse fetal testicular cells

(2012) P. Tartarin et al.   HUMAN REPRODUCTION

Unconjugated bisphenol A cord blood levels in boys with descended or undescended testes

(2012) P. Fenichel et al.   HUMAN REPRODUCTION

Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: the Generation R Study

(2012) C. A. Snijder et al.   HUMAN REPRODUCTION

Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis

(2012) D. M. Kristensen et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Association between chemical pattern in breast milk and congenital cryptorchidism: modelling of complex human exposures

(2012) K. Krysiak-Baltyn et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Do Phthalates Affect Steroidogenesis by the Human Fetal Testis? Exposure of Human Fetal Testis Xenografts to Di-n-Butyl Phthalate

(2012) R. T. Mitchell et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cellular and Molecular Effect of MEHP Involving LXRα in Human Fetal Testis and Ovary

(2012) Vincent Muczynski et al.   PLoS One

Differential Effects of Bisphenol A and Diethylstilbestrol on Human, Rat and Mouse Fetal Leydig Cell Function

(2012) Thierry N’Tumba-Byn et al.   PLoS One

Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches

(2012) V. Muczynski et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In utero exposure to bisphenol-A and anogenital distance of male offspring

(2011) Maohua Miao et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Associations between maternal phthalate exposure and cord sex hormones in human infants

(2011) Lung-Cheng Lin et al.   CHEMOSPHERE

Identification of Phthalates in Medications and Dietary Supplement Formulations in the United States and Canada

(2011) Katherine E. Kelley et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Analgesics During Pregnancy and Undescended Testis

(2011) Claire Philippat et al.   EPIDEMIOLOGY

Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability

(2011) M. S. Jobling et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Foetal exposure to phthalate esters and anogenital distance in male newborns

(2011) Y. Suzuki et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Maternal Cigarette Smoking and Effects on Androgen Action in Male Offspring: Unexpected Effects on Second-Trimester Anogenital Distance

(2011) Paul A. Fowler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A

(2010) Laura N. Vandenberg et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Maternal Use of Acetaminophen, Ibuprofen, and Acetylsalicylic Acid During Pregnancy and Risk of Cryptorchidism

(2010) Morten Søndergaard Jensen et al.   EPIDEMIOLOGY

Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation

(2010) R. T. Mitchell et al.   HUMAN REPRODUCTION

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

(2010) David Møbjerg Kristensen et al.   HUMAN REPRODUCTION

Endocrinology of the mammalian fetal testis

(2010) Peter J O'Shaughnessy et al.   REPRODUCTION

Steroidogenesis in the Fetal Testis and Its Susceptibility to Disruption by Exogenous Compounds

(2009) Hayley M. Scott et al.   ENDOCRINE REVIEWS

Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study

(2009) Julie R Palmer et al.   Environmental Health

Cadmium Increases Human Fetal Germ Cell Apoptosis

(2009) Gaëlle Angenard et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmoset

(2009) C. McKinnell et al.   HUMAN REPRODUCTION

Maternal Smoking and Developmental Changes in Luteinizing Hormone (LH) and the LH Receptor in the Fetal Testis

(2009) Paul A. Fowler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Fetal Leydig Cell Origin and Development

(2009) S.L. Griswold et al.   Sexual Development

Phthalates Impair Germ Cell Number in the Mouse Fetal Testis by an Androgen- and Estrogen-Independent Mechanism

(2009) Abdelali Lehraiki et al.   TOXICOLOGICAL SCIENCES

Determination of total and free mono-n-butyl phthalate in human urine samples after medication of a di-n-butyl phthalate containing capsule

(2009) Elcim Seckin et al.   TOXICOLOGY LETTERS

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

Antifungal drugs and the risk of selected birth defects

(2008) Tonia C. Carter et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Association between prenatal exposure to phthalates and the health of newborns☆

(2008) P HUANG et al.   ENVIRONMENT INTERNATIONAL

Time- and Dose-Related Effects of Di-(2-ethylhexyl) Phthalate and Its Main Metabolites on the Function of the Rat Fetal Testis in Vitro

(2008) François Chauvigné et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Medications as a Potential Source of Exposure to Phthalates in the U.S. Population

(2008) Sonia Hernández-Díaz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Phthalates Impair Germ Cell Development in the Human Fetal Testis in Vitro without Change in Testosterone Production

(2008) Romain Lambrot et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans

(2008) Shanna H. Swan   ENVIRONMENTAL RESEARCH

Factors controlling testis descent

(2008) Ieuan A Hughes et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

(2008) Richard M. Sharpe et al.   FERTILITY AND STERILITY

Germ cell differentiation in the marmoset (Callithrix jacchus) during fetal and neonatal life closely parallels that in the human

(2008) R.T. Mitchell et al.   HUMAN REPRODUCTION

Maternal use of fluconazole and risk of congenital malformations: a Danish population-based cohort study

(2008) M. Norgaard et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism

(2008) Michelle Welsh et al.   JOURNAL OF CLINICAL INVESTIGATION

Risk Factors for Congenital Cryptorchidism in a Prospective Birth Cohort Study

(2008) Ida N. Damgaard et al.   PLoS One

Testicular Dysgenesis Syndrome and the Estrogen Hypothesis: A Quantitative Meta-Analysis

(2007) Olwenn V. Martin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Pregnancy outcome in women with inflammatory bowel disease following exposure to 5-aminosalicylic acid drugs: A meta-analysis

(2007) Roja Rahimi et al.   REPRODUCTIVE TOXICOLOGY