Metformin exposure affects human and mouse fetal testicular cells

AMPK Activation by Dihydrotestosterone Reduces FSH-Stimulated Cell Proliferation in Rat Granulosa Cells by Inhibiting ERK Signaling Pathway

(2012) Pradeep P. Kayampilly et al.   ENDOCRINOLOGY

Early Metformin Therapy (Age 8–12 Years) in Girls with Precocious Pubarche to Reduce Hirsutism, Androgen Excess, and Oligomenorrhea in Adolescence

(2011) Lourdes Ibáñez et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

Mono-(2-ethylhexyl) Phthalate Directly Alters the Expression of Leydig Cell Genes and CYP17 Lyase Activity in Cultured Rat Fetal Testis

(2011) François Chauvigné et al.   PLoS One

In vitro effects of Uranium on human fetal germ cells

(2011) Gaëlle Angenard et al.   REPRODUCTIVE TOXICOLOGY

Metformin Decreases GnRH- and Activin-Induced Gonadotropin Secretion in Rat Pituitary Cells: Potential Involvement of Adenosine 5' Monophosphate-Activated Protein Kinase (PRKA)

(2010) L. Tosca et al.   BIOLOGY OF REPRODUCTION

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

Pharmacokinetics of Metformin during Pregnancy

(2010) S. Eyal et al.   DRUG METABOLISM AND DISPOSITION

Metformin during Pregnancy in Polycystic Ovary Syndrome: Another Vitamin Bites the Dust

(2010) Richard S. Legro   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

(2010) Marc Foretz et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Metformin in the Treatment of Gestational Diabetes

(2009) Terri M Wensel   ANNALS OF PHARMACOTHERAPY

Are We Optimizing Gestational Diabetes Treatment With Glyburide? The Pharmacologic Basis for Better Clinical Practice

(2009) MF Hebert et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Cadmium Increases Human Fetal Germ Cell Apoptosis

(2009) Gaëlle Angenard et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome

(2009) Evanthia Diamanti-Kandarakis et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Metformin influence on hormone levels at birth, in PCOS mothers and their newborns

(2009) S.M. Carlsen et al.   HUMAN REPRODUCTION

Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

(2009) R. Rattan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phthalates Impair Germ Cell Number in the Mouse Fetal Testis by an Androgen- and Estrogen-Independent Mechanism

(2009) Abdelali Lehraiki et al.   TOXICOLOGICAL SCIENCES

Follicle-Stimulating Hormone Inhibits Adenosine 5′-Monophosphate-Activated Protein Kinase Activation and Promotes Cell Proliferation of Primary Granulosa Cells in Culture through an Akt-Dependent Pathway

(2008) Pradeep P. Kayampilly et al.   ENDOCRINOLOGY

Stimulation of Lactate Production in Human Granulosa Cells by Metformin and Potential Involvement of Adenosine 5′ Monophosphate-Activated Protein Kinase

(2008) Malcolm C. Richardson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism

(2008) Michelle Welsh et al.   JOURNAL OF CLINICAL INVESTIGATION

Determination of metformin transfer across the human placenta using a dually perfused ex vivo placental cotyledon model

(2007) Michal Kovo et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology