Nonsense-mediated mRNA decay efficiency varies in choroideremia providing a target to boost small molecule therapeutics
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Title
Nonsense-mediated mRNA decay efficiency varies in choroideremia providing a target to boost small molecule therapeutics
Authors
Keywords
-
Journal
HUMAN MOLECULAR GENETICS
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2019-01-24
DOI
10.1093/hmg/ddz028
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Related references
Note: Only part of the references are listed.- The effect of PTC124 on choroideremia fibroblasts and iPSC-derived RPE raises considerations for therapy
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- Control of gene expression through the nonsense-mediated RNA decay pathway
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- Functional rescue of REP1 following treatment with PTC124 and novel derivative PTC-414 in human choroideremia fibroblasts and the nonsense-mediated zebrafish model
- (2016) Mariya Moosajee et al. HUMAN MOLECULAR GENETICS
- The rules and impact of nonsense-mediated mRNA decay in human cancers
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- Synthesis and activity of a novel inhibitor of nonsense-mediated mRNA decay
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- Analysis of a large choroideremia dataset does not suggest a preference for inclusion of certain genotypes in future trials of gene therapy
- (2016) Paul R. Freund et al. Molecular Genetics & Genomic Medicine
- Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity
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- Clinical utility gene card for: Choroideremia
- (2013) Mariya Moosajee et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Nonsense-mediated mRNA decay: Inter-individual variability and human disease
- (2013) Lam Son Nguyen et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression
- (2013) Kim M. Keeling et al. PLoS One
- Rescue of nonsense mutations by amlexanox in human cells
- (2012) Sara Gonzalez-Hilarion et al. Orphanet Journal of Rare Diseases
- Statistical Analysis of Readthrough Levels for Nonsense Mutations in Mammalian Cells Reveals a Major Determinant of Response to Gentamicin
- (2012) Célia Floquet et al. PLoS Genetics
- Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations
- (2011) I. Peixeiro et al. NUCLEIC ACIDS RESEARCH
- Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues
- (2008) Almoutassem B Zetoune et al. BMC GENETICS
- Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial
- (2008) Eitan Kerem et al. LANCET
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