Activation Profile ofMycobacterium tuberculosis–Specific CD4+T Cells Reflects Disease Activity Irrespective of HIV Status

Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response

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Transformative tools for tackling tuberculosis

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CD4+ T cell polyfunctional profile in HIV-TB coinfection are similar between individuals with latent and active TB infection

(2015) David H. Canaday et al.   TUBERCULOSIS

Multifunctional Analysis of CD4+T-Cell Response as Immune-Based Model for Tuberculosis Detection

(2015) Miriam Lichtner et al.   Journal of Immunology Research

Polyfunctional T-cells and effector memory phenotype are associated with active TB in HIV-infected patients

(2014) Teresa Chiacchio et al.   JOURNAL OF INFECTION

Assessment of the novel T-cell activation marker–tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study

(2014) Damien Portevin et al.   LANCET INFECTIOUS DISEASES

HIV-associated chronic immune activation

(2013) Mirko Paiardini et al.   IMMUNOLOGICAL REVIEWS

T-Cell Immunophenotyping Distinguishes Active From Latent Tuberculosis

(2013) Katrina M. Pollock et al.   JOURNAL OF INFECTIOUS DISEASES

Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study

(2013) Myrsini Kaforou et al.   PLOS MEDICINE

Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease

(2011) Alexandre Harari et al.   NATURE MEDICINE