Transformative tools for tackling tuberculosis

Rapid microbiological screening for tuberculosis in HIV-positive patients on the first day of acute hospital admission by systematic testing of urine samples using Xpert MTB/RIF: a prospective cohort in South Africa

(2015) Stephen D. Lawn et al.   BMC Medicine

Tuberculosis vaccines: barriers and prospects on the quest for a transformative tool

(2015) Christopher L. Karp et al.   IMMUNOLOGICAL REVIEWS

Quality of tuberculosis care in India: a systematic review

(2015) S. Satyanarayana et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response

(2015) Toidi Adekambi et al.   JOURNAL OF CLINICAL INVESTIGATION

Adjunctive biomarkers for improving diagnosis of tuberculosis and monitoring therapeutic effects

(2015) Yun-Gyoung Hur et al.   JOURNAL OF INFECTION

Utility of propidium monoazide viability assay as a biomarker for a tuberculosis disease

(2015) Vladyslav Nikolayevskyy et al.   TUBERCULOSIS

The diagnostic targeting of a carbohydrate virulence factor from M.Tuberculosis

(2015) Conrad E. Chan et al.   Scientific Reports

A Sensitive Urinary Lipoarabinomannan Test for Tuberculosis

(2015) Beston Hamasur et al.   PLoS One

Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

(2014) Anca Dorhoi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The identification of tuberculosis biomarkers in human urine samples

(2014) B. L. Young et al.   EUROPEAN RESPIRATORY JOURNAL

Value of procalcitonin in differentiating pulmonary tuberculosis from other pulmonary infections: a meta-analysis

(2014) S-L. Huang et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Diagnostic Accuracy of a Rapid Urine Lipoarabinomannan Test for Tuberculosis in HIV-Infected Adults

(2014) Lydia Nakiyingi et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing inMycobacterium tuberculosis–Infected Macrophages

(2014) Finlay W. McNab et al.   JOURNAL OF IMMUNOLOGY

Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Christopher J L Murray et al.   LANCET

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

(2014) Katrin D. Mayer-Barber et al.   NATURE

A Trial of Mass Isoniazid Preventive Therapy for Tuberculosis Control

(2014) Gavin J. Churchyard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa

(2014) Suzanne T. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis

(2014) Stephen H. Gillespie et al.   NEW ENGLAND JOURNAL OF MEDICINE

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis

(2014) R. Y. Chen et al.   Science Translational Medicine

Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis

(2014) Payam Nahid et al.   TUBERCULOSIS

Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments

(2014) Grant Theron et al.   Scientific Reports

Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis

(2014) A. Roy et al.   BMJ-British Medical Journal

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

(2013) Philana Ling Lin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials

(2013) Punam Mangtani et al.   CLINICAL INFECTIOUS DISEASES

Influenza A Virus Impairs Control of Mycobacterium tuberculosis Coinfection Through a Type I Interferon Receptor–Dependent Pathway

(2013) Paul S. Redford et al.   JOURNAL OF INFECTIOUS DISEASES

Making wider use of the world's most widely used vaccine: Bacille Calmette-Guerin revaccination reconsidered

(2013) C. Dye   Journal of the Royal Society Interface

Differential Expression of Host Biomarkers in Saliva and Serum Samples from Individuals with Suspected Pulmonary Tuberculosis

(2013) Khutso G. Phalane et al.   MEDIATORS OF INFLAMMATION

Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

(2013) Iñaki Comas et al.   NATURE GENETICS

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

Plasma Heme Oxygenase-1 Levels Distinguish Latent or Successfully Treated Human Tuberculosis from Active Disease

(2013) Bruno B. Andrade et al.   PLoS One

Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers

(2013) Chloe I. Bloom et al.   PLoS One

miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis

(2013) Paolo Miotto et al.   PLoS One

Screening and Identification of Six Serum microRNAs as Novel Potential Combination Biomarkers for Pulmonary Tuberculosis Diagnosis

(2013) Xing Zhang et al.   PLoS One

CD271+ Bone Marrow Mesenchymal Stem Cells May Provide a Niche for Dormant Mycobacterium tuberculosis

(2013) B. Das et al.   Science Translational Medicine

Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study

(2013) Myrsini Kaforou et al.   PLOS MEDICINE

Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment

(2013) Sven O Friedrich et al.   Lancet Respiratory Medicine

Identifying Predictors of Interferon-γ Release Assay Results in Pediatric Latent Tuberculosis: A Protective Role of Bacillus Calmette-Guérin?

(2012) Robindra Basu Roy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Seasonality of Tuberculosis in the United States, 1993-2008

(2012) M. D. Willis et al.   CLINICAL INFECTIOUS DISEASES

Diagnostic accuracy of same-day microscopy versus standard microscopy for pulmonary tuberculosis: a systematic review and meta-analysis

(2012) J Lucian Davis et al.   LANCET INFECTIOUS DISEASES

Effect of Standard Tuberculosis Treatment on Plasma Cytokine Levels in Patients with Active Pulmonary Tuberculosis

(2012) Catherine Riou et al.   PLoS One

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

(2012) Chloe I. Bloom et al.   PLoS One

Common patterns and disease-related signatures in tuberculosis and sarcoidosis

(2012) J. Maertzdorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lower prevalence of tuberculosis infection in BCG vaccinees: a cross-sectional study in adult prison inmates

(2012) Pei-Chun Chan et al.   THORAX

Rapid detection of Mycobacterium tuberculosis biomarkers in a sandwich immunoassay format using a waveguide-based optical biosensor

(2012) Harshini Mukundan et al.   TUBERCULOSIS

Serodiagnostic markers for the prediction of the outcome of intensive phase tuberculosis therapy

(2012) Ralf Baumann et al.   TUBERCULOSIS

Evaluation of a nested-pcr for Mycobacterium tuberculosis detection in blood and urine samples

(2011) Heidi Lacerda Alves da Cruz et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis

(2011) J. Minion et al.   EUROPEAN RESPIRATORY JOURNAL

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

(2011) David G. Russell   IMMUNOLOGICAL REVIEWS

The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection

(2011) Philana Ling Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Tuberculosis in Antiretroviral Treatment Services in Resource-Limited Settings: Addressing the Challenges of Screening and Diagnosis

(2011) Stephen D. Lawn et al.   JOURNAL OF INFECTIOUS DISEASES

WHO recommends against inaccurate tuberculosis tests

(2011) Kelly Morris   LANCET

Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis

(2011) Keriann M Backus et al.   Nature Chemical Biology

Novel Biomarkers Distinguishing Active Tuberculosis from Latent Infection Identified by Gene Expression Profile of Peripheral Blood Mononuclear Cells

(2011) Chanyi Lu et al.   PLoS One

Longitudinal Analysis of QuantiFERON-TB Gold In-Tube in Children with Adult Household Tuberculosis Contact in South Africa: A Prospective Cohort Study

(2011) Maunank Shah et al.   PLoS One

Functional Correlations of Pathogenesis-Driven Gene Expression Signatures in Tuberculosis

(2011) Jeroen Maertzdorf et al.   PLoS One

Transcriptional responses of host peripheral blood cells to tuberculosis infection

(2011) Emil Lesho et al.   TUBERCULOSIS

Natural infection of guinea pigs exposed to patients with highly drug-resistant tuberculosis

(2011) Ashwin S. Dharmadhikari et al.   TUBERCULOSIS

Evidence of an effect of BCG revaccination on incidence of tuberculosis in school-aged children in Brazil: Second report of the BCG-REVAC cluster-randomised trial

(2011) Mauricio L. Barreto et al.   VACCINE

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Rapid Molecular Detection of Tuberculosis and Rifampin Resistance

(2010) Catharina C. Boehme et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dynamic antibody responses to the Mycobacterium tuberculosis proteome

(2010) S. Kunnath-Velayudhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuberculosis: What We Don't Know Can, and Does, Hurt Us

(2010) D. G. Russell et al.   SCIENCE

Breath biomarkers of active pulmonary tuberculosis

(2010) Michael Phillips et al.   TUBERCULOSIS

Resuscitation-promoting Factors Reveal an Occult Population of Tubercle Bacilli in Sputum

(2009) Galina V. Mukamolova et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

(2009) Clifton E. Barry et al.   NATURE REVIEWS MICROBIOLOGY

BCG vaccination reduces risk of infection with Mycobacterium tuberculosis as detected by gamma interferon release assay

(2009) Michael Eisenhut et al.   VACCINE

Identification of Mycobacterium tuberculosis Ornithine Carboamyltransferase in Urine as a Possible Molecular Marker of Active Pulmonary Tuberculosis

(2008) D. R. Napolitano et al.   Clinical and Vaccine Immunology

Immune activation and IL-12 production during acute/early HIV infection in the absence and presence of highly active, antiretroviral therapy

(2008) Adriana A. Byrnes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum

(2008) Natalie J Garton et al.   PLOS MEDICINE