Article
Reproductive Biology
Hao Tian, Qi Qi, Fengxiang Yan, Chunxin Wang, Fujun Hou, Weimin Ren, Li Zhang, Jian Hou
Summary: Supplementation of prepubertal oocytes with sericin and FLI in IVM medium significantly improved the blastocyst development rate, suggesting the potential for enhancing the developmental competence of oocytes in juvenile in vitro embryo transfer technology. These findings may contribute to the advancement of assisted reproductive technologies in relevant fields.
Article
Biochemistry & Molecular Biology
Marjaneh Pournaghi, Rasa Khodavirdilou, Mohammad Ali Ebrahimi Saadatlou, Fatemeh Sokouti Nasimi, Soodabeh Yousefi, Halimeh Mobarak, Masoud Darabi, Vahideh Shahnazi, Reza Rahbarghazi, Mahdi Mahdipour
Summary: Melatonin was found to significantly affect the release of exosomes from bovine cumulus cells, increasing cell viability and reducing exosome diameter. Additionally, melatonin can impact the expression of specific genes in exosomes and alter the fatty acid composition.
PROCESS BIOCHEMISTRY
(2021)
Article
Endocrinology & Metabolism
Desmond A. R. Tutt, Gizem Guven-Ates, Wing Yee Kwong, Rob Simmons, Fei Sang, Giuseppe Silvestri, Carla Canedo-Ribeiro, Alan H. Handyside, Remi Labrecque, Marc-Andre Sirard, Richard D. Emes, Darren K. Griffin, Kevin D. Sinclair
Summary: Removing complex proteins during bovine IVM affects the metabolism of cumulus cells. The addition of melatonin is beneficial in the presence of complex proteins but detrimental in their absence. These findings lay the foundation for developing chemically defined IVM systems for the generation of cytogenetically and epigenetically normal embryos.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Cell Biology
Tianqi Zhu, Shengyu Guan, Dongying Lv, Mengmeng Zhao, Laiqing Yan, Li Shi, Pengyun Ji, Lu Zhang, Guoshi Liu
Summary: The study established methods to monitor lipid metabolism in single live oocytes using probes. It was found that both lipid biogenesis and lipolysis occurred during oocyte maturation, but the total lipid level decreased. Melatonin rescued disrupted lipid metabolism and maturation in porcine oocytes treated with certain inhibitors, highlighting its potential in improving oocyte developmental competence. Additionally, the presence of melatonin receptors in cumulus cells and their impact on gene expression related to antioxidants, lipid metabolism, and mitochondrial respiration were observed, providing further insights into the mechanism of melatonin's effect on oocyte maturation.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Endocrinology & Metabolism
Wenkui Ma, Hao Wu, Guangdong Li, Laiqing Yan, Likai Wang, Mengmeng Zhao, Shengyu Guan, Shang Xu, Xiaokai Guo, Fenze Liu, Pengyun Ji, Abulizi Wusiman, Guoshi Liu
Summary: Melatonin promotes the growth and development of lambs by regulating gene expression and intestinal microbial flora.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Reproductive Biology
Li-Xin Cui, Ya-Qing Tian, Hai-Sheng Hao, Hui-Ying Zou, Yun-Wei Pang, Shan-Jiang Zhao, Xue-Ming Zhao, Hua-Bin Zhu, Wei-Hua Du
Summary: This study investigated the expression and function of ASH1L methyltransferase in bovine cumulus cells, focusing on its role in regulating epigenetic modification, apoptosis, and gene expression in the cells. The results showed that ASH1L knockdown led to decreased histone methylation, inhibited cell proliferation, increased apoptosis, and upregulated expression of apoptosis-related genes. The study also revealed an increase in mRNA levels of PRC2 protein subunits EZH2 and SUZ12 in cells with ASH1L knockdown.
Review
Biochemistry & Molecular Biology
David Gonzalez-Flores, Laura Lopez-Pingarron, Maria Yolanda Castano, Maria Angeles Gomez, Ana B. Rodriguez, Joaquin J. Garcia, Maria Garrido
Summary: Fibromyalgia syndrome (FMS) is a chronic pain syndrome accompanied by various symptoms. Nonpharmacological remedies, such as melatonin, have shown promising results in relieving pain and improving mood and sleep disturbances in FMS patients. Studies have also explored the relationship between mitochondrial dysfunction, oxidative stress, and FMS, suggesting potential mechanisms for this syndrome. The use of melatonin as a coadjuvant therapy may be a successful strategy for managing FMS.
Article
Endocrinology & Metabolism
Haroon Ejaz, Juliana K. Figaro, Andrea M. F. Woolner, Bensita M. V. Thottakam, Helen F. Galley
Summary: Maternal melatonin production is higher in pregnant women compared to non-pregnant women, increases throughout pregnancy, peaks in the third trimester, and decreases abruptly after delivery. The placenta appears to be a major source of melatonin, supporting its physiological role in pregnancy.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Horticulture
Naveed Ahmad, Muhammad Naeem, Hina Ali, Khulood Fahad Alabbosh, Hamad Hussain, Ismail Khan, Shahrood Ahmed Siddiqui, Asif Ali Khan, Babar Iqbal
Summary: In the face of escalating environmental challenges, plants encounter complex combinations of abiotic stresses. Recent advancements have revealed the multifaceted role of melatonin in plant stress responses, including its involvement in redox regulation and epigenetic signaling. Melatonin acts as a versatile ally, counteracting oxidative damage caused by abiotic stress and shaping stress-responsive gene networks in plants. However, the precise mechanisms by which melatonin coordinates redox regulation and epigenetic signaling to enhance plant resilience to various abiotic stresses remain unclear. This study explores the current advancements, knowledge gaps, and future directions of melatonin-induced redox regulation and epigenetic signaling, offering hope for sustainable agricultural production in the face of mounting environmental challenges.
SCIENTIA HORTICULTURAE
(2023)
Article
Endocrinology & Metabolism
Jian Zhang, Huali Jiang, Kunpeng Du, Tao Xie, Baiyao Wang, Chengcong Chen, Russel J. Reiter, Bohong Cen, Yawei Yuan
Summary: Melatonin plays protective roles in cancer, and this study revealed the genomic alteration and clinical characteristics of melatonergic regulators in 33 cancers. Methylation-mediated downregulation of melatonergic regulator expression and the association with patient survival prediction were identified. A miRNA-mRNA interaction network involved in melatonin secretion and metabolism, as well as pathways related to inhibition of apoptosis, DNA damage response, cell cycle, and signaling activation, were also uncovered.
JOURNAL OF PINEAL RESEARCH
(2021)
Article
Endocrinology & Metabolism
Tianshu Han, Wenbo Jiang, Huanyu Wu, Wei Wei, Jiang Lu, Huimin Lu, Jiaxu Xu, Wenbo Gu, Xiaoyu Guo, Yu Wang, Jingqi Ruan, Yunong Li, Yuxin Wang, Xitao Jiang, Shengnan Zhao, Ying Li, Changhao Sun
Summary: This study found that fetal malnutrition can impair melatonin synthesis through hypermethylation of PRKCA and CREB1 promoters, but these effects cannot be transmitted to the next generation.
JOURNAL OF PINEAL RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Amirhossein Davoodvandi, Banafsheh Nikfar, Russel J. Reiter, Zatollah Asemi
Summary: Melatonin plays important roles in mammals, regulating circadian rhythms, enhancing immunity, and inhibiting cancer. Epigenetic drugs have gained attention for their potential in cancer treatment. This report summarizes the effects of melatonin on DNA methylation in cancer cells and discusses the impact of artificial light on melatonin secretion and cancer cell DNA methylation.
CELLULAR & MOLECULAR BIOLOGY LETTERS
(2022)
Article
Reproductive Biology
Irene Sanchez-Ajofrin, Alicia Martin-Maestro, Daniela Alejandra Medina-Chavez, Juan Angel Laborda-Gomariz, Patricia Peris-Frau, Jose Julian Garde, Ana Josefa Soler
Summary: This study investigated the protective effects of melatonin on oocyte development after prolonged ovarian preservation. The results demonstrated that an appropriate concentration of melatonin can enhance oocyte development potential, reduce cell apoptosis, alleviate oxidative stress, and improve embryo quality.
Article
Veterinary Sciences
Vitor L. Molosse, Guilherme L. Deolindo, Bruno G. Cecere, Hiam Marcon, Gilneia da Rosa, Marcelo Vedovatto, Claiton A. Zotti, Anielen D. Silva, Mateus Fracasso, Vera M. Morsch, Raissa A. Carvalho, Wanderson A. B. Pereira, Aleksandro S. Da Silva
Summary: The study showed that supplementing suckling lambs' diet with grape residue flour improved their health and promoted growth by stimulating antioxidant and immune systems.
RESEARCH IN VETERINARY SCIENCE
(2021)
Article
Horticulture
Yuxia Li, Lei Zhang, Long Zhang, Ghazala Nawaz, Chenxu Zhao, Jian Zhang, Qinghe Cao, Tingting Dong, Tao Xu
Summary: This study found that exogenous MT can effectively delay the browning process of fresh-cut sweetpotato by reducing enzyme activities related to browning and decreasing ROS levels. MT treatment also maintains higher levels of antioxidants, inhibiting browning and prolonging the shelf life of fresh-cut sweetpotato.
SCIENTIA HORTICULTURAE
(2022)
Article
Materials Science, Multidisciplinary
Qiang Li, Fei Li, Junjie Li, Zhi Gao, Ke Zhang, Mitsuo Niinomi, Takayoshi Nakano
Summary: By replacing Nb with Cr, the stability and comprehensive mechanical properties of beta-type Ti-Nb-Cr alloys can be improved without causing cytotoxicity.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2022)
Review
Chemistry, Inorganic & Nuclear
Linan Wang, Qi Sun, Junjie Li
Summary: As the core device of all-solid-state laser, infrared (IR) nonlinear optical (NLO) material plays a critical role in various applications. This review summarizes the progress of high-performance sulfide IR NLO materials since 2018, focusing on their synthesis, crystal structure, optical properties, and structure-property relationship. The potential opportunities and challenges in IR NLO materials are also discussed.
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Jiawei Yang, Qiang Li, Junjie Li, Jinshuai Yang, Ran Zhang, Mitsuo Niinomi, Takayoshi Nakano
Summary: Cu-doped hydroxyapatite/TiO2 composite coatings were prepared using an electrochemical method, resulting in improved adhesion and antibacterial properties. These coatings showed high biocompatibility and promoted cell proliferation.
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
(2023)
Article
Chemistry, Multidisciplinary
Jiazheng Zhou, Zhongxu Fan, Kewang Zhang, Zhihua Yang, Shilie Pan, Junjie Li
MATERIALS HORIZONS
(2023)
Article
Optics
Miriding Mutailipu, Jian Han, Zhi Li, Fuming Li, Junjie Li, Fangfang Zhang, Xifa Long, Zhihua Yang, Shilie Pan
Summary: Researchers propose a full-wavelength phase-matching crystal that can avoid phase-mismatching throughout its entire optical transparency range. The anisotropic bonding strength in the energy dimension is confirmed to be the key to achieve this ability. They demonstrate a guanidinium tetrafluoroborate crystal that can be phase-matched over its entire optical transparency range, generating harmonic light as short as 193.2 nm. This work lays the foundation for finding a new class of crystals with full-wavelength phase-matching and provides a high-performance crystal for generating 266 nm light.
Article
Chemistry, Multidisciplinary
Linan Wang, Chenchen Tu, Hongbo Gao, Jiazheng Zhou, Hongshan Wang, Zhihua Yang, Shilie Pan, Junjie Li
Summary: Two new infrared birefringent materials, AMgGeSe(3) (A = Li, Na), with large optical anisotropy were designed by a combined strategy of rigid octahedron and flexible dimer. The results showed that LiMgGeSe3 exhibited a birefringence of 0.334@1,064 nm, while NaMgGeSe3 had the largest reported birefringence of 0.445@1,064 nm among dimer-contained selenides. The influence of polarizability anisotropy, density, arrangement of units, and layer distance on birefringence was highlighted by density functional theory calculations and statistical analyses.
SCIENCE CHINA-CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Jiazheng Zhou, Linan Wang, Yu Chu, Hongshan Wang, Shilie Pan, Junjie Li
Summary: Through introducing fluorination into chalcogenides, a wide bandgap IR NLO material Na3SiS3F with unprecedented [SiS3F] tetrahedra is designed and synthesized. Na3SiS3F exhibits a wide bandgap of 4.75 eV, high laser damage induced threshold (approximately 5 times that of AgGaS2), moderate NLO response, large birefringence, and wide IR transparent region. This research provides a promising IR NLO material for high-power laser applications and opens up a new avenue for the design of new wide bandgap IR NLO materials based on NLO-active [SiSiF4-x] (x = 1, 2, 3) mixed anionic tetrahedral group.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Qi Sun, Loukya Boddapati, Linan Wang, Junjie Li, Francis Leonard Deepak
Summary: Crystallization is crucial in determining the size, purity, and structure of crystals. Understanding the growth dynamics of nanoparticles at the atomic level is essential for the controlled fabrication of nanocrystals with desired properties. In this study, the growth of Au nanorods was observed in situ at the atomic scale using an aberration-corrected transmission electron microscope. The attachment of spherical colloidal Au nanoparticles involved the formation and growth of neck-like structures, followed by five-fold twin intermediate states and atomic rearrangement. Statistical analyses revealed that the length and diameter of Au nanorods can be regulated by the number and size of colloidal Au nanoparticles. This study provides insights into the fabrication of Au nanorods using irradiation chemistry.
Article
Chemistry, Physical
Xinzhu Gao, Quan Chen, Qinggang Qin, Liang Li, Meizhuang Liu, Derek Hao, Junjie Li, Jingbo Li, Zhongchang Wang, Zuxin Chen
Summary: By intelligently designing a tri-gate two-dimensional ferroelectric van der Waals heterostructures device using copper indium thiophosphate and few layers tungsten disulfide, the researchers demonstrate its versatile applications in multi-valued data, non-volatile storage, and logic operations. The device can flexibly switch functions at a low supply voltage, offering a high switching ratio and low subthreshold swing.
Article
Chemistry, Multidisciplinary
Yu Chu, Hongshan Wang, Tudi Abutukadi, Zhi Li, Miriding Mutailipu, Xin Su, Zhihua Yang, Junjie Li, Shilie Pan
Summary: An unprecedented wide bandgap Hg-based IR NLO material Zn2HgP2S8 (ZHPS) with diamond-like structure is rationally designed and fabricated by a tetrahedron re-organization strategy with the aid of structure and property predictions. ZHPS exhibits a wide bandgap of 3.37 eV, which is the largest one among the reported Hg-based chalcogenide IR NLO materials and first breaks the 3.0 eV bandgap wall in this system, resulting in a high laser-induced damage threshold (LIDT) of similar to 2.2 x AgGaS2 (AGS). Meanwhile, it shows a large NLO response (1.1 x AGS), achieving a good balance between bandgap (>= 3.0 eV) and NLO effect (>= 1 x AGS) for an excellent IR NLO material.
Article
Materials Science, Multidisciplinary
Linan Wang, Chenchen Tu, Jiazheng Zhou, Yu Chu, Zhihua Yang, Shilie Pan, Junjie Li
Summary: In this article, two halogenated metal chalcogenides Cs3Ga8S13Cl and Cs9Ga8Se12Cl9 with unprecedented [GaQ(3)Cl] (Q = S/Se) tetrahedral units were designed and fabricated by introducing a halogen into the NLO-active tetrahedral unit. Among them, Cs3Ga8S13Cl material has a large bandgap and a moderate NLO response, making it suitable for high-power infrared laser applications.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Linan Wang, Dongdong Chu, Deqiang Yin, Congwei Xie, Zhihua Yang, Junjie Li, Shilie Pan
Summary: By coupling [BeSe4] with NLO-active [GaSe4] tetrahedral groups, the researchers predicted the formation of one thermodynamically stable and three metastable defective diamond-like (DL) BeGa2Se4 (BeGSe) compounds. Notably, BeGSe-II and BeGSe-III showed high thermal conductivities and achieved a good balance between wide band gap and large NLO effect, making them excellent candidates for infrared NLO materials.
MATERIALS TODAY PHYSICS
(2023)
Article
Chemistry, Inorganic & Nuclear
Jiazheng Zhou, Xin Su, Ling Luo, Junjie Li, Feng Yu
Summary: Two new alkaline metal thioboratephosphates, RbB3P2S10 and CsB3P2S10, were synthesized by the flux method. These compounds consist of alkali metal polyhedral and [B6P4S20] T3-supertetrahedral units, and crystallize in I4(1)/a and R3c space groups, respectively. The findings expand the chemical diversity of chalcogenides and provide insights for the exploration of new functional materials in thioboratephosphates.
DALTON TRANSACTIONS
(2023)
Article
Green & Sustainable Science & Technology
Mingyue Wang, Shengzhe Chu, Qiang Wei, Chunjie Tian, Yi Fang, Guang Chen, Sitong Zhang
Summary: Soil pollution is a crucial field in the current global ecological environmental problems. Research efforts are focused on soil remediation and biological detoxification to achieve the remediation of contaminated soil. The aim is to establish a virtuous ecological cycle and provide a biological basis for sustainable utilization and development of resources.
Article
Chemistry, Inorganic & Nuclear
Hongshan Wang, Xueting Pan, Wang Zhao, Yu Chu, Junjie Li
Summary: Developing high-performance infrared nonlinear optical materials is crucial for laser technology. Three new alkaline earth metal sulfides, including BaZnGeS4, have been developed based on electronic structure engineering and experimental investigations. BaZnGeS4 exhibits a good balance between NLO response and band gap, making it an excellent IR NLO material.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Correction
Biochemistry & Molecular Biology
Siew Chin Chan, Chih-Wei Tung, Chia-Wei Lin, Yun-Shiuan Tung, Po-Min Wu, Pei-Hsun Cheng, Chuan-Mu Chen, Shang-Hsun Yang
FREE RADICAL BIOLOGY AND MEDICINE
(2024)
Article
Biochemistry & Molecular Biology
Suyuan Liu, Meiling Tan, Jiangxue Cai, Chenxuan Li, Miaoxin Yang, Xiaoxiao Sun, Bin He
Summary: This study reveals that the antibiotic doxycycline effectively inhibits NLRP3 inflammasome activation by targeting mitochondrial translation and mtDNA synthesis, offering potential for the treatment of NLRP3-related diseases.
FREE RADICAL BIOLOGY AND MEDICINE
(2024)
Article
Biochemistry & Molecular Biology
Hao Liu, Nana Li, Ge Kuang, Xia Gong, Ting Wang, Jun Hu, Hui Du, Minxuan Zhong, Jiashi Guo, Yao Xie, Yang Xiang, Shengwang Wu, Yiling Yuan, Xinru Yin, Jingyuan Wan, Ke Li
Summary: Protectin D1 (PTD1) improves hepatic steatosis, inflammation and fibrosis in a NASH mouse model by inhibiting the activation of TLR4 downstream signaling pathway, possibly through upregulation of IRAK-M expression, suggesting a potential new treatment for NASH.
FREE RADICAL BIOLOGY AND MEDICINE
(2024)