Pan‐cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer

Melatonin interrupts osteoclast functioning and suppresses tumor-secreted RANKL expression: implications for bone metastases

(2021) Po-I Liu et al.   ONCOGENE

Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle

(2021) Yool Lee et al.   Science Advances

An updated review of mechanistic potentials of melatonin against cancer: pivotal roles in angiogenesis, apoptosis, autophagy, endoplasmic reticulum stress and oxidative stress

(2021) Saeed Mehrzadi et al.   Cancer Cell International

Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities

(2021) Wamidh H. Talib et al.   MOLECULES

Isoform-Specific Lysine Methylation of RORα2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression

(2020) Hyerin Song et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome

(2020) Shang Li et al.   Translational Research

Melatonin reverses nasopharyngeal carcinoma cisplatin chemoresistance by inhibiting the Wnt/β-catenin signaling pathway

(2020) Jian Zhang et al.   Aging-US

KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer

(2020) Hunain Alam et al.   CANCER CELL

Melatonin: an endogenous miraculous indolamine, fights against cancer progression

(2020) Saptadip Samanta   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Melatonergic system of AANAT, melatonin and its receptor MT2 in the corpus luteum are essential for reproductive success in mammals

(2020) Jing Wang et al.   BIOLOGY OF REPRODUCTION

Melatonin downregulates TRPC6, impairing store-operated calcium entry in triple negative breast cancer cells.

(2020) Isaac Jardin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin impedes prostate cancer metastasis by suppressing MMP‐13 expression

(2020) Shih‐Wei Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pan-cancer Genomic Analyses Reveal Prognostic and Immunogenic Features of the Tumor Melatonergic Microenvironment Across 14 Solid Cancer Types

(2019) Jia-Wei Lv et al.   JOURNAL OF PINEAL RESEARCH

Research on circadian clock genes in common abdominal malignant tumors

(2019) Meng-jun Qiu et al.   CHRONOBIOLOGY INTERNATIONAL

Circadian (De)regulation in Head and Neck Squamous Cell Carcinoma

(2019) Sadia Rahman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Circadian clock associates with tumor microenvironment in thoracic cancers

(2019) Yong Yang et al.   Aging-US

Rotating Night Shift work and Colorectal Cancer Risk in the Nurses' Health Studies

(2018) Kyriaki Papantoniou et al.   INTERNATIONAL JOURNAL OF CANCER

DNA methylation accumulation in gastric mucosa adjacent to cancer after Helicobacter pylori eradication

(2018) Sayumi Tahara et al.   INTERNATIONAL JOURNAL OF CANCER

Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland

(2018) Dun Tan et al.   MOLECULES

Sleep and circadian disruption and incident breast cancer risk: An evidence-based and theoretical review

(2018) Laura B. Samuelsson et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy

(2018) Youqiong Ye et al.   Cell Systems

Maftools: efficient and comprehensive analysis of somatic variants in cancer

(2018) Anand Mayakonda et al.   GENOME RESEARCH

BMAL1 but not CLOCK is associated with monochromatic green light-induced circadian rhythm of melatonin in chick pinealocytes

(2018) Shuhui Ma et al.   Endocrine Connections

GSK3 activity regulates rhythms in hippocampal clock gene expression and synaptic plasticity

(2017) Rachel C. Besing et al.   HIPPOCAMPUS

An ancestral haplotype of the human PERIOD2 gene associates with reduced sensitivity to light-induced melatonin suppression

(2017) Tokiho Akiyama et al.   PLoS One

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

Circadian Rhythmicity of Active GSK3 Isoforms Modulates Molecular Clock Gene Rhythms in the Suprachiasmatic Nucleus

(2015) Rachel C. Besing et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Correlating chemical sensitivity and basal gene expression reveals mechanism of action

(2015) Matthew G Rees et al.   Nature Chemical Biology

RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D

(2014) Andrzej T. Slominski et al.   FASEB JOURNAL

Melatonin feedback on clock genes: a theory involving the proteasome

(2014) Jerry Vriend et al.   JOURNAL OF PINEAL RESEARCH

A pan-cancer proteomic perspective on The Cancer Genome Atlas

(2014) Rehan Akbani et al.   Nature Communications

Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway

(2012) Hany Goubran Botros et al.   JOURNAL OF PINEAL RESEARCH

A Role for the Melatonin-Related Receptor GPR50 in Leptin Signaling, Adaptive Thermogenesis, and Torpor

(2011) David A. Bechtold et al.   CURRENT BIOLOGY

Relating CNVs to transcriptome data at fine resolution: Assessment of the effect of variant size, type, and overlap with functional regions

(2011) A. Schlattl et al.   GENOME RESEARCH

Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways

(2008) S PANDIPERUMAL et al.   PROGRESS IN NEUROBIOLOGY