Carbohydrate–protein interactions and multivalency: implications for the inhibition of influenza A virus infections

Sialyllactose-Modified Three-Way Junction DNA as Binding Inhibitor of Influenza Virus Hemagglutinin

(2018) Miyuki Yamabe et al.   BIOCONJUGATE CHEMISTRY

Multivalent neuraminidase hydrolysis resistant triazole-sialoside protein conjugates as influenza-adsorbents

(2018) Xin Meng et al.   CHINESE CHEMICAL LETTERS

Influenza

(2018) Florian Krammer et al.   Nature Reviews Disease Primers

Combination Therapy With Neuraminidase and Polymerase Inhibitors in Nude Mice Infected With Influenza Virus

(2017) Maki Kiso et al.   JOURNAL OF INFECTIOUS DISEASES

Spatial Screening of Hemagglutinin on Influenza A Virus Particles: Sialyl-LacNAc Displays on DNA and PEG Scaffolds Reveal the Requirements for Bivalency Enhanced Interactions with Weak Monovalent Binders

(2017) Victor Bandlow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics

(2017) Julie Elisabeth Heggelund et al.   Scientific Reports

Pentacyclic triterpenes grafted on CD cores to interfere with influenza virus entry: A dramatic multivalent effect

(2016) Sulong Xiao et al.   BIOMATERIALS

Multivalent S-sialoside protein conjugates block influenza hemagglutinin and neuraminidase

(2016) Yang Yang et al.   CARBOHYDRATE RESEARCH

Investigational hemagglutinin-targeted influenza virus inhibitors

(2016) Li-Yan Zeng et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses

(2016) Lifeng Fu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Functional Characterization of Cholera Toxin Inhibitors Using Human Intestinal Organoids

(2016) Domenique D. Zomer-van Ommen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nanostructured glycan architecture is important in the inhibition of influenza A virus infection

(2016) Seok-Joon Kwon et al.   Nature Nanotechnology

Anti-Hemagglutinin Antibody Derived Lead Peptides for Inhibitors of Influenza Virus Binding

(2016) Henry Memczak et al.   PLoS One

Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA

(2015) Ricardo Visini et al.   ACS Chemical Biology

Protein-Carbohydrate Interactions as Part of Plant Defense and Animal Immunity

(2015) Kristof De Schutter et al.   MOLECULES

Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection

(2015) Antonio Muñoz et al.   Nature Chemistry

S-Linked sialyloligosaccharides bearing liposomes and micelles as influenza virus inhibitors

(2015) Hsien-Wei Yeh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Protein-Based Pentavalent Inhibitor of the Cholera Toxin B-Subunit

(2014) Thomas R. Branson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antiviral strategies against influenza virus: towards new therapeutic approaches

(2014) Arianna Loregian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of receptor binding specificity in influenza A virus transmission and pathogenesis

(2014) M. de Graaf et al.   EMBO JOURNAL

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

Bridging lectin binding sites by multivalent carbohydrates

(2013) Valentin Wittmann et al.   CHEMICAL SOCIETY REVIEWS

Optimizing Divalent Inhibitors ofPseudomonas aeruginosaLectin LecA by Using A Rigid Spacer

(2013) Francesca Pertici et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Multivalent Carbohydrate-Centered Glycoclusters as Nanomolar Ligands of the Bacterial Lectin LecA fromPseudomonas aeruginosa

(2013) Marina L. Gening et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Nanomolar Multivalent Ligand as Entry Inhibitor of the Hemagglutinin of Avian Influenza

(2013) Moritz Waldmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanomolar cholera toxininhibitors based on symmetrical pentavalent ganglioside GM1os-sym-corannulenes

(2013) Martin Mattarella et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Picomolar inhibition of cholera toxin by a pentavalent ganglioside GM1os-calix[5]arene

(2013) Jaime Garcia-Hartjes et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Influenza virus hemagglutinin stalk-based antibodies and vaccines

(2013) Florian Krammer et al.   Current Opinion in Virology

Potent divalent inhibitors with rigid glucose click spacers for Pseudomonas aeruginosa lectin LecA

(2012) Francesca Pertici et al.   CHEMICAL COMMUNICATIONS

Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs

(2012) Enguang Feng et al.   ChemMedChem

A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin LecA and of Pseudomonas aeruginosa Biofilms

(2011) Rameshwar U. Kadam et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbohydrate-Functionalized Chitosan Fiber for Influenza Virus Capture

(2011) Xuebing Li et al.   BIOMACROMOLECULES

Inhibition of Influenza Virus Activity by Multivalent Glycoarchitectures with Matched Sizes

(2011) Ilona Papp et al.   CHEMBIOCHEM

Synthesis of Dodecavalent Fullerene-Based Glycoclusters and Evaluation of Their Binding Properties towards a Bacterial Lectin

(2011) Samy Cecioni et al.   CHEMISTRY-A EUROPEAN JOURNAL

CuAAC synthesis of resorcin[4]arene-based glycoclusters as multivalent ligands of lectins

(2011) Zahid H. Soomro et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Novel trivalent anti-influenza reagent

(2010) Fei Feng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of Influenza Virus Infection by Multivalent Sialic-Acid-Functionalized Gold Nanoparticles

(2010) Ilona Papp et al.   Small

Achieving High Affinity towards a Bacterial Lectin through Multivalent Topological Isomers of Calix[4]arene Glycoconjugates

(2009) Samy Cecioni et al.   CHEMISTRY-A EUROPEAN JOURNAL

From carbohydrate leads to glycomimetic drugs

(2009) Beat Ernst et al.   NATURE REVIEWS DRUG DISCOVERY

Detection of Intact Influenza Viruses using Biotinylated BiantennaryS-Sialosides

(2008) Ramesh R. Kale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of sialoclusters appended to calix[4]arene platforms via multiple azide-alkyne cycloaddition. New inhibitors of hemagglutination and cytopathic effect mediated by BK and influenza A viruses

(2008) Alberto Marra et al.   ORGANIC & BIOMOLECULAR CHEMISTRY