Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics

PaxVax CVD 103-HgR single-dose live oral cholera vaccine

(2017) Myron M. Levine et al.   Expert Review of Vaccines

Fighting Cholera One-on-One: The Development and Efficacy of Multivalent Cholera-Toxin-Binding Molecules

(2016) Han Zuilhof   ACCOUNTS OF CHEMICAL RESEARCH

Single-dose Live Oral Cholera Vaccine CVD 103-HgR Protects Against Human Experimental Infection WithVibrio choleraeO1 El Tor

(2016) Wilbur H. Chen et al.   CLINICAL INFECTIOUS DISEASES

Editorial Commentary: Resurrecting a Live Oral Cholera Vaccine

(2016) Jason B. Harris   CLINICAL INFECTIOUS DISEASES

Functional Characterization of Cholera Toxin Inhibitors Using Human Intestinal Organoids

(2016) Domenique D. Zomer-van Ommen et al.   JOURNAL OF MEDICINAL CHEMISTRY

High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence

(2016) Julie Elisabeth Heggelund et al.   PLoS Pathogens

Online data analysis at the ESRF bioSAXS beamline, BM29

(2016) Martha Elisabeth Brennich et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds

(2016) Patrick Cherubin et al.   PLoS One

Assessing and maximizing data quality in macromolecular crystallography

(2015) P Andrew Karplus et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Updated Global Burden of Cholera in Endemic Countries

(2015) Mohammad Ali et al.   PLoS Neglected Tropical Diseases

Tetra- versus Pentavalent Inhibitors of Cholera Toxin

(2015) Ou Fu et al.   ChemistryOpen

Fucosylation and protein glycosylation create functional receptors for cholera toxin

(2015) Amberlyn M Wands et al.   eLife

ISPyB for BioSAXS, the gateway to user autonomy in solution scattering experiments

(2015) Alejandro De Maria Antolinos et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

BioSAXS Sample Changer: a robotic sample changer for rapid and reliable high-throughput X-ray solution scattering experiments

(2015) Adam Round et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Protein-Based Pentavalent Inhibitor of the Cholera Toxin B-Subunit

(2014) Thomas R. Branson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comprehensive analysis of blood group antigen binding to classical and El Tor cholera toxin B-pentamers by NMR

(2014) Francesca Vasile et al.   GLYCOBIOLOGY

Synthesis, Biological Evaluation, WAC and NMR Studies ofS-Galactosides and Non-Carbohydrate Ligands of Cholera Toxin Based on Polyhydroxyalkylfuroate Moieties

(2013) Javier Ramos-Soriano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Upgraded ESRF BM29 beamline for SAXS on macromolecules in solution

(2013) Petra Pernot et al.   JOURNAL OF SYNCHROTRON RADIATION

Nanomolar cholera toxininhibitors based on symmetrical pentavalent ganglioside GM1os-sym-corannulenes

(2013) Martin Mattarella et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Picomolar inhibition of cholera toxin by a pentavalent ganglioside GM1os-calix[5]arene

(2013) Jaime Garcia-Hartjes et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Grape Extracts Inhibit Multiple Events in the Cell Biology of Cholera Intoxication

(2013) Srikar Reddy et al.   PLoS One

Towards a Structural Basis for the Relationship Between Blood Group and the Severity of El Tor Cholera

(2012) Pintu K. Mandal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Both El Tor and classical cholera toxin bind blood group determinants

(2012) Julie E. Heggelund et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bacterial toxininhibitors based on multivalent scaffolds

(2012) Thomas R. Branson et al.   CHEMICAL SOCIETY REVIEWS

ID29: a high-intensity highly automated ESRF beamline for macromolecular crystallography experiments exploiting anomalous scattering

(2012) Daniele de Sanctis et al.   JOURNAL OF SYNCHROTRON RADIATION

Cholera

(2012) Jason B Harris et al.   LANCET

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular basis of cholera blood-group dependence and implications for a world characterized by climate change

(2010) Åsa Holmner et al.   FEBS LETTERS

Crystal Structures Exploring the Origins of the Broader Specificity of Escherichia coli Heat-Labile Enterotoxin Compared to Cholera Toxin

(2010) Åsa Holmner et al.   JOURNAL OF MOLECULAR BIOLOGY

MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments

(2010) José Gabadinho et al.   JOURNAL OF SYNCHROTRON RADIATION

Antibiotics for Both Moderate and Severe Cholera

(2010) Eric J. Nelson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide

(2010) Ethan A. Merritt et al.   PROTEIN SCIENCE

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Synthesis and Affinity Evaluation of a Small Library of Bidentate Cholera Toxin Ligands: Towards Nonhydrolyzable Ganglioside Mimics

(2009) Pavel Cheshev et al.   CHEMISTRY-A EUROPEAN JOURNAL

The MORPHEUS protein crystallization screen

(2009) Fabrice Gorrec   JOURNAL OF APPLIED CRYSTALLOGRAPHY

The Influence of Ligand Valency on Aggregation Mechanisms for Inhibiting Bacterial Toxins

(2008) Cristina Sisu et al.   CHEMBIOCHEM

Cholera Toxin Inhibitors Studied with High-Performance Liquid Affinity Chromatography: A Robust Method to Evaluate Receptor-Ligand Interactions

(2008) Maria Bergström et al.   Chemical Biology & Drug Design

Interfering with the Sugar Code: Design and Synthesis of Oligosaccharide Mimics

(2008) Anna Bernardi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Vaccination with Dukoral®against travelers’ diarrhea (ETEC) and cholera

(2008) Tomas Jelinek et al.   Expert Review of Vaccines

CHAINSAW: a program for mutating pdb files used as templates in molecular replacement

(2008) Norman Stein   JOURNAL OF APPLIED CRYSTALLOGRAPHY