The protective effect of kaempferol on heart via the regulation of Nrf2, NF-κβ, and PI3K/Akt/GSK-3β signaling pathways in isoproterenol-induced heart failure in diabetic rats

Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases

(2018) Abdoh Taleb et al.   BIOMEDICINE & PHARMACOTHERAPY

Cardiovascular disease (CVD) and associated risk factors among older adults in six low-and middle-income countries: results from SAGE Wave 1

(2018) Ye Ruan et al.   BMC PUBLIC HEALTH

Comparison of speckle-tracking echocardiography with invasive hemodynamics for the detection of characteristic cardiac dysfunction in type-1 and type-2 diabetic rat models

(2018) Csaba Mátyás et al.   Cardiovascular Diabetology

Do the SGLT-2 Inhibitors Offer More than Hypoglycemic Activity?

(2018) Eduardo Flores et al.   CARDIOVASCULAR DRUGS AND THERAPY

Effect of Kaempferol Pretreatment on Myocardial Injury in Rats

(2018) Anamika Vishwakarma et al.   Cardiovascular Toxicology

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and down-regulating TLR4/MyD88 pathway

(2018) Xiao Cheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Protective and therapeutic effects of dexpanthenol on isoproterenol-induced cardiac damage in rats

(2018) Ferhat Kalkan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Advanced Heart Failure Patients With Left Ventricular Assist Devices and Heart Transplantation Have Altered Oral Microbial Diversity Alongside Endotoxemia, Inflammation and Oxidative Stress

(2018) M. Yuzefpolskaya et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Kaempferol ameliorates hyperglycemia through suppressing hepatic gluconeogenesis and enhancing hepatic insulin sensitivity in diet-induced obese mice

(2018) Hana Alkhalidy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol

(2018) Jingqiu Wang et al.   PLoS One

Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study

(2018) Araz Rawshani et al.   LANCET

The Flavonoid Kaempferol Ameliorates Streptozotocin-Induced Diabetes by Suppressing Hepatic Glucose Production

(2018) Hana Alkhalidy et al.   MOLECULES

Kaempferol attenuates cognitive deficit via regulating oxidative stress and neuroinflammation in an ovariectomized rat model of sporadic dementia

(2018) Parvin Babaei et al.   Neural Regeneration Research

Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells

(2018) Tae Woo Kim et al.   Cell Death & Disease

Molecular Pathways Involved in the Amelioration of Myocardial Injury in Diabetic Rats by Kaempferol

(2017) Kapil Suchal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

1,25-Dihydroxyvitamin-D3 prevents the development of diabetic cardiomyopathy in type 1 diabetic rats by enhancing autophagy via inhibiting the β-catenin/TCF4/GSK-3β/mTOR pathway

(2017) Huili Wei et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Nrf2/Keap1/ARE Pathway and Oxidative Stress as a Therapeutic Target in Type II Diabetes Mellitus

(2017) Joshua A. David et al.   Journal of Diabetes Research

Sphingosine-1-Phosphate Receptor Agonist Fingolimod Increases Myocardial Salvage and Decreases Adverse Postinfarction Left Ventricular Remodeling in a Porcine Model of Ischemia/ReperfusionCLINICAL PERSPECTIVE

(2016) Carlos G. Santos-Gallego et al.   CIRCULATION

Methanolic seed extract of Vitis vinifera ameliorates oxidative stress, inflammation and ATPase dysfunction in infarcted and non-infarcted heart of streptozotocin–nicotinamide induced male diabetic rats

(2016) Nelli Giribabu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Kaempferol Attenuates Myocardial Ischemic InjuryviaInhibition of MAPK Signaling Pathway in Experimental Model of Myocardial Ischemia-Reperfusion Injury

(2016) Kapil Suchal et al.   Oxidative Medicine and Cellular Longevity

Mutations in the Corneal Endothelial Dystrophy–Associated Gene SLC4A11 Render the Cells More Vulnerable to Oxidative Insults

(2015) Sanhita Roy et al.   CORNEA

Potential drugs which activate nuclear factor E2-related factor 2 signaling to prevent diabetic cardiovascular complications: A focus on fumaric acid esters

(2015) Shanshan Zhou et al.   LIFE SCIENCES

Protective Effects of Kaempferol against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart via Antioxidant Activity and Inhibition of Glycogen Synthase Kinase-3β

(2015) Mingjie Zhou et al.   Oxidative Medicine and Cellular Longevity

Influence of kaempferol, a flavonoid compound, on membrane-bound ATPases in streptozotocin-induced diabetic rats

(2015) Khalid S. Al-Numair et al.   PHARMACEUTICAL BIOLOGY

Kaempferol and inflammation: From chemistry to medicine

(2015) Kasi Pandima Devi et al.   PHARMACOLOGICAL RESEARCH

The anti-obesity and anti-diabetic effects of kaempferol glycosides from unripe soybean leaves in high-fat-diet mice

(2015) Yanqing Zang et al.   Food & Function

Amelioration of Isoproterenol-Induced Oxidative Damage in Rat Myocardium byWithania somniferaLeaf Extract

(2015) Md. Ibrahim Khalil et al.   Biomed Research International

Small Molecule Kaempferol Promotes Insulin Sensitivity and Preserved Pancreaticβ-Cell Mass in Middle-Aged Obese Diabetic Mice

(2015) Hana Alkhalidy et al.   Journal of Diabetes Research

The case for inhibiting p38 mitogen-activated protein kinase in heart failure

(2015) Pelin Arabacilar et al.   Frontiers in Pharmacology

Chlorophytum borivilianum Root Extract Maintains near Normal Blood Glucose, Insulin and Lipid Profile Levels and Prevents Oxidative Stress in the Pancreas of Streptozotocin-Induced Adult Male Diabetic Rats

(2014) Nelli Giribabu et al.   International Journal of Medical Sciences

Ameliorative effect of kaempferol, a flavonoid, on oxidative stress in streptozotocin-induced diabetic rats

(2014) Khalid S. Al-Numair et al.   REDOX REPORT

Neuroprotective Effect of Kaempferol Glycosides against Brain Injury and Neuroinflammation by Inhibiting the Activation of NF-κB and STAT3 in Transient Focal Stroke

(2013) Lu Yu et al.   PLoS One

Assessing left ventricular systolic dysfunction after myocardial infarction: are ejection fraction and dP/dtmax complementary or redundant?

(2012) Kiyotake Ishikawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Diabetic cardiomyopathy: pathophysiology and clinical features

(2012) Takayuki Miki et al.   HEART FAILURE REVIEWS

Activation of the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway during Porcine Circovirus Type 2 Infection Facilitates Cell Survival and Viral Replication

(2012) L. Wei et al.   JOURNAL OF VIROLOGY

Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3beta dependent pathway in experimental diabetic cardiomyopathy

(2011) Dongdong Sun et al.   Cardiovascular Diabetology

Glycaemic control and incidence of heart failure in 20 985 patients with type 1 diabetes: an observational study

(2011) Marcus Lind et al.   LANCET

A Review on the Dietary Flavonoid Kaempferol

(2011) J. M. Calderon-Montano et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro

(2011) Jing Xiao et al.   TOXICOLOGY

Insulin attenuates myocardial ischemia/reperfusion injury via reducing oxidative/nitrative stress

(2010) Lele Ji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

(2010) Albena T. Dinkova-Kostova et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Inactivation of GSK-3  by Metallothionein Prevents Diabetes-Related Changes in Cardiac Energy Metabolism, Inflammation, Nitrosative Damage, and Remodeling

(2009) Y. Wang et al.   DIABETES

Control of mitochondrial apoptosis by the Bcl-2 family

(2009) J. K. Brunelle et al.   JOURNAL OF CELL SCIENCE

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

Targeting NF- B in Waldenstrom macroglobulinemia

(2008) X. Leleu et al.   BLOOD