Hepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium

Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell Function

(2016) Benjamin D. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of alanyl aminopeptidase (CD13) as a surface marker for isolation of mature gastric zymogenic chief cells

(2015) Benjamin D. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Systems Biology Approach Identifies a Regulatory Network in Parotid Acinar Cell Terminal Differentiation

(2015) Melissa A. Metzler et al.   PLoS One

Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract

(2015) Jason C. Mills et al.   Science Signaling

Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract

(2015) Jason C. Mills et al.   Science Signaling

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

The Hyaluronic Acid Receptor CD44 Coordinates Normal and Metaplastic Gastric Epithelial Progenitor Cell Proliferation

(2013) Shradha S. Khurana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multidomain integration in the structure of the HNF-4α nuclear receptor complex

(2013) Vikas Chandra et al.   NATURE

Anks4b, a Novel Target of HNF4α Protein, Interacts with GRP78 Protein and Regulates Endoplasmic Reticulum Stress-induced Apoptosis in Pancreatic β-Cells

(2012) Yoshifumi Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors

(2012) Bin Fang et al.   NUCLEIC ACIDS RESEARCH

Scaling factors: Transcription factors regulating subcellular domains

(2011) Jason C. Mills et al.   BIOESSAYS

The origin of pre-neoplastic metaplasia in the stomach: Chief cells emerge from the Mist

(2011) James R. Goldenring et al.   EXPERIMENTAL CELL RESEARCH

Extensive Pancreas Regeneration Following Acinar-Specific Disruption of Xbp1 in Mice

(2011) David A. Hess et al.   GASTROENTEROLOGY

Tamoxifen Induces Rapid, Reversible Atrophy, and Metaplasia in Mouse Stomach

(2011) Won Jae Huh et al.   GASTROENTEROLOGY

The Transcription Factor MIST1 Is a Novel Human Gastric Chief Cell Marker Whose Expression Is Lost in Metaplasia, Dysplasia, and Carcinoma

(2010) Jochen K.M. Lennerz et al.   AMERICAN JOURNAL OF PATHOLOGY

Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of “floxed” alleles

(2010) Won Jae Huh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum

(2010) Won Jae Huh et al.   GASTROENTEROLOGY

Spasmolytic Polypeptide-Expressing Metaplasia and Intestinal Metaplasia: Time for Reevaluation of Metaplasias and the Origins of Gastric Cancer

(2010) James R. Goldenring et al.   GASTROENTEROLOGY

Mature Chief Cells Are Cryptic Progenitors for Metaplasia in the Stomach

(2010) Ki Taek Nam et al.   GASTROENTEROLOGY

Gastric Epithelial Stem Cells

(2010) Jason C. Mills et al.   GASTROENTEROLOGY

Developmental and Tissue-Specific Regulation of Hepatocyte Nuclear Factor 4-α (HNF4-α) Isoforms in Rodents

(2010) SAMENA DEAN et al.   GENE EXPRESSION

Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells

(2010) Benjamin J. Capoccia et al.   PHYSIOLOGICAL GENOMICS

Hepatocyte nuclear factor 4α contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation

(2009) Jean-Philippe Babeu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

(2009) Derrick J. Todd et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hepatocyte Nuclear Factor 4 , a Key Factor for Homeostasis, Cell Architecture, and Barrier Function of the Adult Intestinal Epithelium

(2009) A.-L. Cattin et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of Hepatocyte-Nuclear-Factor-4α Affects Colonic Ion Transport and Causes Chronic Inflammation Resembling Inflammatory Bowel Disease in Mice

(2009) Mathieu Darsigny et al.   PLoS One

The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage

(2008) Andrew J. Bredemeyer et al.   DEVELOPMENTAL BIOLOGY

Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease

(2008) Sung-Hoon Ahn et al.   INFLAMMATORY BOWEL DISEASES