Multidomain integration in the structure of the HNF-4α nuclear receptor complex

Evidence for DNA-Binding Domain-Ligand-Binding Domain Communications in the Androgen Receptor

(2012) C. Helsen et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors

(2012) Bin Fang et al.   NUCLEIC ACIDS RESEARCH

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

(2011) Jang Hyun Choi et al.   NATURE

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

(2011) Natacha Rochel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations

(2010) S E Flanagan et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

(2010) Jang Hyun Choi et al.   NATURE

Hyperinsulinaemic hypoglycaemia

(2009) R R Kapoor et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Integrated approach for the identification of human hepatocyte nuclear factor 4α target genes using protein binding microarrays

(2009) Eugene Bolotin et al.   HEPATOLOGY

Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing

(2009) Ola Wallerman et al.   NUCLEIC ACIDS RESEARCH

Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor

(2009) Xiaohui Yuan et al.   PLoS One

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Genome-wide profiling of PPAR :RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

(2008) R. Nielsen et al.   GENES & DEVELOPMENT

Structural Basis of Natural Promoter Recognition by a Unique Nuclear Receptor, HNF4α

(2008) Peng Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Farnesoid X Receptor by Protein Kinase C Promotes Its Transcriptional Activity

(2008) Romain Gineste et al.   MOLECULAR ENDOCRINOLOGY

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE