Does the muscle protein synthetic response to exercise and amino acid-based nutrition diminish with advancing age? A systematic review
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Title
Does the muscle protein synthetic response to exercise and amino acid-based nutrition diminish with advancing age? A systematic review
Authors
Keywords
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Volume 311, Issue 5, Pages E803-E817
Publisher
American Physiological Society
Online
2016-08-24
DOI
10.1152/ajpendo.00213.2016
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Note: Only part of the references are listed.- Fast-digestive protein supplement for ten days overcomes muscle anabolic resistance in healthy elderly men
- (2016) Stéphane Walrand et al. CLINICAL NUTRITION
- The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply
- (2015) W. Kyle Mitchell et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Obesity Appears to Be Associated With Altered Muscle Protein Synthetic and Breakdown Responses to Increased Nutrient Delivery in Older Men, but Not Reduced Muscle Mass or Contractile Function
- (2015) Andrew J. Murton et al. DIABETES
- MECHANISMS IN ENDOCRINOLOGY: Exogenous insulin does not increase muscle protein synthesis rate when administered systemically: a systematic review
- (2015) J. Trommelen et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women
- (2015) Melissa M. Markofski et al. EXPERIMENTAL GERONTOLOGY
- How Sedentary Are Older People? A Systematic Review of the Amount of Sedentary Behavior
- (2015) Juliet A. Harvey et al. JOURNAL OF AGING AND PHYSICAL ACTIVITY
- Impact of the Macronutrient Composition of a Nutritional Supplement on Muscle Protein Synthesis Rates in Older Men: A Randomized, Double Blind, Controlled Trial
- (2015) Irene Fleur Kramer et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Skeletal Muscle Anabolic Response to Plant- versus Animal-Based Protein Consumption
- (2015) Stephan van Vliet et al. JOURNAL OF NUTRITION
- Aging Is Accompanied by a Blunted Muscle Protein Synthetic Response to Protein Ingestion
- (2015) Benjamin Toby Wall et al. PLoS One
- Muscle Mass Index As a Predictor of Longevity in Older Adults
- (2014) Preethi Srikanthan et al. AMERICAN JOURNAL OF MEDICINE
- Influence of aerobic exercise intensity on myofibrillar and mitochondrial protein synthesis in young men during early and late postexercise recovery
- (2014) Danielle M. Di Donato et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group
- (2014) Nicolaas E.P. Deutz et al. CLINICAL NUTRITION
- Lipid-Induced Insulin Resistance Is Associated With an Impaired Skeletal Muscle Protein Synthetic Response to Amino Acid Ingestion in Healthy Young Men
- (2014) Francis B. Stephens et al. DIABETES
- Carbohydrate Coingestion Delays Dietary Protein Digestion and Absorption but Does Not Modulate Postprandial Muscle Protein Accretion
- (2014) Stefan H. M. Gorissen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2014) Andreas Bornø et al. JOURNAL OF MASS SPECTROMETRY
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- (2014) Jared M. Dickinson et al. JOURNAL OF NUTRITION
- Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Population-Based Cohort Study of Older Men
- (2014) Janice L. Atkins et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Protein Ingestion to Stimulate Myofibrillar Protein Synthesis Requires Greater Relative Protein Intakes in Healthy Older Versus Younger Men
- (2014) D. R. Moore et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Keeping Older Muscle “Young” through Dietary Protein and Physical Activity
- (2014) Daniel R. Moore Advances in Nutrition
- The muscle protein synthetic response to the combined ingestion of protein and carbohydrate is not impaired in healthy older men
- (2013) Alexandra Kiskini et al. AGE
- Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise
- (2013) Oliver C Witard et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Anabolic Resistance of Muscle Protein Synthesis with Aging
- (2013) Nicholas A. Burd et al. EXERCISE AND SPORT SCIENCES REVIEWS
- The decline in skeletal muscle mass with aging is mainly attributed to a reduction in type II muscle fiber size
- (2013) Rachel Nilwik et al. EXPERIMENTAL GERONTOLOGY
- Disuse Impairs the Muscle Protein Synthetic Response to Protein Ingestion in Healthy Men
- (2013) Benjamin T. Wall et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Two Weeks of Reduced Activity Decreases Leg Lean Mass and Induces “Anabolic Resistance” of Myofibrillar Protein Synthesis in Healthy Elderly
- (2013) Leigh Breen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group
- (2013) Jürgen Bauer et al. Journal of the American Medical Directors Association
- Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis
- (2012) Naomi M Cermak et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults
- (2012) Kyle L Timmerman et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
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- (2012) Yifan Yang et al. BRITISH JOURNAL OF NUTRITION
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- (2012) Nicholas A. Burd et al. BRITISH JOURNAL OF NUTRITION
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- (2012) Jared M. Dickinson et al. CLINICAL NUTRITION
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- (2012) Cheyne E. Donges et al. JOURNAL OF APPLIED PHYSIOLOGY
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- (2012) Michael Tieland et al. Journal of the American Medical Directors Association
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- (2012) C. S. Fry et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Leucine content of dietary proteins is a determinant of postprandial skeletal muscle protein synthesis in adult rats
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- (2010) Bart Pennings et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling
- (2010) Philip J Atherton et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
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- (2010) Erin L. Glynn et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Evolution of sarcopenia research
- (2010) Ian Janssen Applied Physiology Nutrition and Metabolism
- Sarcopenia: characteristics, mechanisms and functional significance
- (2010) M. V. Narici et al. BRITISH MEDICAL BULLETIN
- Age-related anabolic resistance after endurance-type exercise in healthy humans
- (2010) William J. Durham et al. FASEB JOURNAL
- Human muscle protein turnover—why is it so variable?
- (2010) Gordon I. Smith et al. JOURNAL OF APPLIED PHYSIOLOGY
- Excess Leucine Intake Enhances Muscle Anabolic Signaling but Not Net Protein Anabolism in Young Men and Women
- (2010) Erin L. Glynn et al. JOURNAL OF NUTRITION
- The anabolic response to resistance exercise and a protein-rich meal is not diminished by age
- (2010) T. B. Symonsi et al. Journal of Nutrition Health & Aging
- Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein
- (2010) Juha J Hulmi et al. Nutrition & Metabolism
- Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia
- (2009) Emilie A Wilkes et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells
- (2009) Philip J. Atherton et al. AMINO ACIDS
- Anabolic resistance: the effects of aging, sexual dimorphism, and immobilization on human muscle protein turnoverThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.
- (2009) Michael J. Rennie Applied Physiology Nutrition and Metabolism
- Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism
- (2009) S. Fujita et al. DIABETOLOGIA
- Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
- (2009) David L. Mayhew et al. JOURNAL OF APPLIED PHYSIOLOGY
- Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men
- (2009) Jason E. Tang et al. JOURNAL OF APPLIED PHYSIOLOGY
- Dietary Protein Digestion and Absorption Rates and the Subsequent Postprandial Muscle Protein Synthetic Response Do Not Differ between Young and Elderly Men
- (2009) René Koopman et al. JOURNAL OF NUTRITION
- Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats
- (2009) Michèle Balage et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise
- (2009) Daniel R. Moore et al. JOURNAL OF PHYSIOLOGY-LONDON
- A Moderate Serving of High-Quality Protein Maximally Stimulates Skeletal Muscle Protein Synthesis in Young and Elderly Subjects
- (2009) T. Brock Symons et al. JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION
- Physical Activity in the United States Measured by Accelerometer
- (2009) RICHARD P. TROIANO et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men
- (2008) Daniel R Moore et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging
- (2008) Micah J. Drummond et al. JOURNAL OF APPLIED PHYSIOLOGY
- Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion
- (2008) Elisa I. Glover et al. JOURNAL OF PHYSIOLOGY-LONDON
- Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle
- (2008) Sarah B. Wilkinson et al. JOURNAL OF PHYSIOLOGY-LONDON
- Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men
- (2008) Vinod Kumar et al. JOURNAL OF PHYSIOLOGY-LONDON
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