Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice

Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice

(2015) Jessica A. Williams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

ApoA-IV: current and emerging roles in intestinal lipid metabolism, glucose homeostasis, and satiety

(2015) Alison B. Kohan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mechanism of phospho-ubiquitin-induced PARKIN activation

(2015) Tobias Wauer et al.   NATURE

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids

(2015) Daniel F. Vatner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestine-specific Deletion of Acyl-CoA:Monoacylglycerol Acyltransferase (MGAT) 2 Protects Mice from Diet-induced Obesity and Glucose Intolerance

(2014) David W. Nelson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

(2014) Lesley A. Kane et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

(2014) Gerald I. Shulman   NEW ENGLAND JOURNAL OF MEDICINE

Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunction

(2013) Jérôme Piquereau et al.   Autophagy

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

(2013) N. Turner et al.   DIABETOLOGIA

Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption

(2012) Raymond G. Fox et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet

(2012) Megumi Hatori et al.   Cell Metabolism

Timed high-fat diet resets circadian metabolism and prevents obesity

(2012) Hadas Sherman et al.   FASEB JOURNAL

Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control

(2011) Derek P. Narendra et al.   ANTIOXIDANTS & REDOX SIGNALING

Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice

(2011) Michael J. Jurczak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

(2011) Kye-Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

A guide to analysis of mouse energy metabolism

(2011) Matthias H Tschöp et al.   NATURE METHODS

Toward a More Complete (and Less Controversial) Understanding of Energy Expenditure and Its Role in Obesity Pathogenesis

(2010) K. J. Kaiyala et al.   DIABETES

Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice

(2010) J. E. Ayala et al.   Disease Models & Mechanisms

The role of parkin in familial and sporadic Parkinson's disease

(2010) Ted M. Dawson et al.   MOVEMENT DISORDERS

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Age-associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts

(2009) Marco Nooteboom et al.   AGING CELL

Small intestinal disorders in the elderly

(2009) Alan B.R. Thomson   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding

(2009) Chi-Liang Eric Yen et al.   NATURE MEDICINE

Circadian Timing of Food Intake Contributes to Weight Gain

(2009) Deanna M. Arble et al.   Obesity

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Parkin as a tumor suppressor gene for hepatocellular carcinoma

(2008) M Fujiwara et al.   ONCOGENE